Results 151 to 160 of about 104,077 (298)

CD248/Endosialin Regulates Synovial Fibroblast State to Control Coupling of Inflammation and Bone Damage in Murine Models of Immune‐Mediated Inflammatory Arthritis and Aging

open access: yesArthritis &Rheumatology, EarlyView.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/endosialin is expressed by fibroblasts in the synovium, is highly up‐regulated during inflammation, and has been proposed as a potential therapeutic target.
Samuel Kemble   +12 more
wiley   +1 more source

Hydrogen bonding in cocrystals of trans-Ni<sup>II</sup>(hfac)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>. [PDF]

open access: yesActa Crystallogr C Struct Chem
Clemmer GL   +4 more
europepmc   +1 more source

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

open access: yesBMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li   +9 more
wiley   +1 more source

Resolving the biome debate: ecological and palaeo‐data concur that the extensive tree‐limited grassy biomes of central and north‐western Madagascar are largely anthropogenic

open access: yesBiological Reviews, EarlyView.
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph   +7 more
wiley   +1 more source

Regeneration-Optimized Chemisorbents: Evaluating Hybrid Coordination Networks for Atmospheric Water Harvesting. [PDF]

open access: yesAngew Chem Int Ed Engl
Kong XJ   +15 more
europepmc   +1 more source

Extreme Heterogeneity Reported in Published Anatomical Meta‐Analyses: A Meta‐Epidemiological Study

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Following the introduction of meta‐analytic methodology into anatomical research, anatomical meta‐analyses have increased substantially. However, extremely high statistical heterogeneity is frequently observed in these studies, while its implications remain insufficiently discussed within anatomical research. The present study investigated the
Joe Iwanaga   +4 more
wiley   +1 more source

Epistemological Anatomy: A Conceptual Framework for Understanding Anatomical Knowledge

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Anatomy is often regarded as settled knowledge. Yet anatomical propositions differ enormously in their evidentiary foundations, while textbooks and atlases frequently present them with similar certainty. How, then, does an anatomical observation become anatomical knowledge? We introduce epistemological anatomy as a framework for the systematic
Marios Loukas   +5 more
wiley   +1 more source

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