Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/endosialin is expressed by fibroblasts in the synovium, is highly up‐regulated during inflammation, and has been proposed as a potential therapeutic target.
Samuel Kemble +12 more
wiley +1 more source
Hydrogen bonding in cocrystals of trans-Ni<sup>II</sup>(hfac)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>. [PDF]
Clemmer GL +4 more
europepmc +1 more source
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li +9 more
wiley +1 more source
A spectroscopic and <i>in silico</i> study on ruthenium(ii) complexes bearing pyridine-carboxamide ligands interacting with DNA as potential therapeutics. [PDF]
Sookai S +3 more
europepmc +1 more source
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph +7 more
wiley +1 more source
Regeneration-Optimized Chemisorbents: Evaluating Hybrid Coordination Networks for Atmospheric Water Harvesting. [PDF]
Kong XJ +15 more
europepmc +1 more source
Extreme Heterogeneity Reported in Published Anatomical Meta‐Analyses: A Meta‐Epidemiological Study
ABSTRACT Following the introduction of meta‐analytic methodology into anatomical research, anatomical meta‐analyses have increased substantially. However, extremely high statistical heterogeneity is frequently observed in these studies, while its implications remain insufficiently discussed within anatomical research. The present study investigated the
Joe Iwanaga +4 more
wiley +1 more source
Evaluating mHealth app quality for chronic disease management in the Eastern Cape, South Africa: validation of the Chronic Disease Mobile Health Application Quality Evaluation Framework (CHRONIQ) framework. [PDF]
Charlie C, Cilliers L.
europepmc +1 more source
Epistemological Anatomy: A Conceptual Framework for Understanding Anatomical Knowledge
ABSTRACT Anatomy is often regarded as settled knowledge. Yet anatomical propositions differ enormously in their evidentiary foundations, while textbooks and atlases frequently present them with similar certainty. How, then, does an anatomical observation become anatomical knowledge? We introduce epistemological anatomy as a framework for the systematic
Marios Loukas +5 more
wiley +1 more source

