Results 151 to 160 of about 33,882 (227)

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

[Effect and mechanism of adipocyte co-culture on aquaporin-9 expression in HepG2 cells]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2019
Huang TH, Li CF, Qiu LW, Liao ST, Mei ZC.   +4 more
europepmc   +1 more source

Investigating the Sensitivity of the Diffusion MRI Signal to Magnetization Transfer and Permeability via Monte‐Carlo Simulations

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 960-974, August 2026.
ABSTRACT Purpose Magnetization transfer (MT) and water exchange via permeability operate on a similar spatiotemporal scale to water diffusion. In this study, we use a simulation‐based approach to characterize how MT and permeability impact (1) diffusion‐weighted MRI (dMRI) measurements from cylindrical substrates and (2) parameter estimation using a ...
Zhiyu Zheng, Karla L. Miller, Benjamin C. Tendler, Michiel Cottaar   +3 more
wiley   +1 more source

Rhizospheric Microbes and Nanoparticles Synergize to Enhance Plant Immune Responses

Plant-Environment Interactions, Volume 7, Issue 4, August 2026.
Nanobiotics integrate engineered nanoparticles with beneficial rhizosphere microbes to synergistically enhance plant immunity, nutrient acquisition, and stress resilience. Multi‐omics and AI‐driven approaches enable precision design, accelerating sustainable, climate‐smart agriculture, and resilient crop production. ABSTRACT Sustainable crop production
Mohammad Nazrul Islam Bhuiyan, Md. Saidur Rahman, Md. Mahfuzur Rahman, Barun Kanti Saha   +3 more
wiley   +1 more source

Levetiracetam inhibits the Na+ HCO3− transporter Ncbe/NBCn2 (Slc4a10) in the choroid plexus of mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim The Na+‐dependent Cl−/HCO3− exchanger Ncbe/NBCn2 (Slc4a10) constitutes a major basolateral HCO3− uptake pathway in the choroid plexus and contributes to cerebrospinal fluid secretion and pH regulation. This study examined whether levetiracetam inhibits Ncbe/NBCn2‐mediated transport and alters cerebrospinal fluid acid–base balance ...
Laura Øllegaard Johnsen, Lasse Messell Desdorf, Nicoline Stærke Jensen, Jeppe Praetorius, Helle Hasager Damkier   +4 more
wiley   +1 more source

Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux. [PDF]

Bioinformation, 2014
Poojan S, Dhasmana A, Jamal QM, Haneef M, Lohani M.   +4 more
europepmc   +1 more source

A Rare Overlap of AQP4 and MOG Seropositivity in Neuromyelitis Optica Spectrum Disorder: A Case Report

Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is an immune‐mediated disorder of the central nervous system associated with autoantibodies against aquaporin‐4 (AQP4). This is distinct from myelin‐oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), defined by anti‐MOG antibodies.
Sarah E. Butler, Siew Kar Chen, Mastura Monif   +2 more
wiley   +1 more source

Genetic Insights Into AVP Deficiency: Identification of a Novel AVP Variant and Compilation of a Curated Catalogue of Pathogenic Variants

Clinical Genetics, Volume 110, Issue 2, Page 203-209, August 2026.
We identified a novel pathogenic AVP variant in two Danish families with autosomal dominant inheritance of symptoms of AVP deficiency. In addition, we compiled a catalogue of additionally 109 AVP variants that cause AVP deficiency and demonstrated the advantage of combining expert‐assisted curation, literature search, and online repositories to ensure ...
Jennifa Joseph, Esben Søndergaard, Sine Knorr, Jane Hagelskjær Knudsen, Søren Rittig, Jane Hvarregaard Christensen   +5 more
wiley   +1 more source