Results 91 to 100 of about 75,608 (261)

Chronic inflammation evoked by pathogenic stimulus during carcinogenesis

open access: yes4 open, 2019
A pathogenic (biological or chemical) stimulus is the earliest information received by a cell that can result in the disruption of homeostasis with consequent development of disease.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Polyspecific, antiviral immune response distinguishes multiple sclerosis and neuromyelitis optica [PDF]

open access: yes, 1887
Background: A polyspecific, intrathecal humoral immune response against neurotropic viruses such as measles, rubella and varicella zoster virus (MRZ reaction, MRZR) is present in 80--100% of patients with multiple sclerosis (MS), but has not to date been
Bergamaschi, R.   +12 more
core   +2 more sources

Arginine Promotes the Expression of Aquaporin-3 and Water Transport in Porcine Trophectoderm Cells Through NO- and cAMP-Dependent Mechanisms [PDF]

open access: gold, 2022
Cui Zhu   +8 more
openalex   +1 more source

Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

open access: yesJournal of Neuroscience, 1997
Membrane water transport is critically involved in brain volume homeostasis and in the pathogenesis of brain edema. The cDNA encoding aquaporin-4 (AQP4) water channel protein was recently isolated from rat brain.
S. Nielsen   +5 more
semanticscholar   +1 more source

Integrating Astrocytes in the Sleep–Wake Cycle: The Time Is Now

open access: yesBioEssays, EarlyView.
Astrocytes actively regulate sleep homeostatic and circadian rheostatic processes, underpinning the sleep–wake cycle. By acting as context‐dependent integrators of internal state and rhythmic environmental inputs, they modulate the encoding properties of neuronal circuitries and contribute to salient temporal representations in the brain.
Marco Brancaccio
wiley   +1 more source

Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]

open access: yes, 2017
Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
core   +2 more sources

Aquaporin-3 in Cancer

open access: yesInternational Journal of Molecular Sciences, 2017
Increasing evidence suggests that the water/glycerol channel aquaporin-3 (AQP3) plays a pivotal role in cancer metastasis. AQP3 knockout mice were resistant to skin tumor formation and overexpression correlated with metastasis and poor prognosis in ...
Saw Marlar   +3 more
semanticscholar   +1 more source

Deserts, Rivers, Pools, and Billabongs: Water Features of the Nitrogenase Proteins, and their Functions

open access: yesChemBioChem, EarlyView.
In the protein surrounding the active site of nitrogenase there is a large anhydrous desert, traversed by two watercourses necessary for the enzyme to convert N2 to NH3. Various pools exist, but their water seems to be stagnant. This review examines the occurrence and function of water inside the protein that contains the catalytic site of the enzyme ...
Ian Dance
wiley   +1 more source

Root ABA accumulation enhances rice seedling drought tolerance under ammonium supply: interaction with aquaporins

open access: yesFrontiers in Plant Science, 2016
In previous studies, we demonstrated that ammonium nutrition enhances the drought tolerance of rice seedlings compared to nitrate nutrition and contributes to a higher root water uptake ability.
Lei Ding   +8 more
doaj   +1 more source

Screening polyoxometalates as aquaporin inhibitors for cancer therapeutics [PDF]

open access: yes, 2019
Aquaporins (AQPs) are transmembrane protein channels that facilitate the diffusion of water and glycerol across cell membranes, crucial for water and energy homeostasis.
Aureliano, M.   +4 more
core  

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