Results 91 to 100 of about 137,242 (267)

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

Advanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan, Haitao Yuan, Wenjun Zhu, Xiaokang Xie, Shen Zhou, Wenzhi Hao, Xiaowei Mo, Lian Yang, Xiaojuan Li, Junshan Liu, Lijuan Deng, Jiaxu Chen   +11 more
wiley   +1 more source

Sustainable Phosphorylated Cellulose Nanocrystals: A Dual‐Affinity Platform for High‐Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides

Advanced Science, EarlyView.
AAA ABSTRACT Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li, Wuming Fan, Xuyang Yue, Dongdong Wang, Xiangyu Tang, Zhuo Zhang, Yonggui Wang, Yanjun Xie, Mingliang Ye, Hongqiang Qin   +9 more
wiley   +1 more source

Ecotoxicology of Nanoparticles in Aquatic Systems

, 2019
Editors: Julian Blasco, Ilaria Corsi. The use of nanoparticles in medicine, industrial, and other applications has triggered an interest in their potential. This book explores the use of nanoparticles related to their occurrence in the environment, their impact on biota in aquatic systems, application of new methodologies, and changes associated with ...
Blasco Julian, Corsi Ilaria
openaire   +4 more sources

A Metal‐Free Molecular Ferroelectric With Large Piezoelectricity and Its Porous Composite for Superior Output Power Density

Advanced Science, EarlyView.
Metal‐free molecular crystal [(CH3C6H10NH3)(18‐crown‐6)][ClO4] functions as a high‐performance molecular ferroelectric. Through strategic methylation of the cyclohexylamine unit, the compound achieves large spontaneous polarization and outstanding piezoelectric coefficients.
Nan Chen, Wenjuan Wei, Le Ye, Lingyu Wan, Yen Wei   +4 more
wiley   +1 more source

Microbial ecology of Antarctic aquatic systems

Nature Reviews Microbiology, 2015
The Earth's biosphere is dominated by cold environments, and the cold biosphere is dominated by microorganisms. Microorganisms in cold Southern Ocean waters are recognized for having crucial roles in global biogeochemical cycles, including carbon sequestration, whereas microorganisms in other Antarctic aquatic biomes are not as well understood. In this
openaire   +3 more sources

Heterogeneous Wettability‐Based Construction of Two‐Phase Interfaces for Underwater Reversible Adhesion

Advanced Science, EarlyView.
The design employs heterogeneous wettability surfaces that construct stable oil‐water interfaces to achieve robust and rapid reversible adhesion. Linear enhancement of adhesion strength is realized through multi‐interface patterning. This adhesive enables rapid on‐demand detachment within five seconds via voltage‐induced electrolysis, offering a level ...
Xiaokai Li, Yonghui Zhang, Yongxin Li, Jiahao Zhang, Yuheng Li, Zhengyu Li, Jianwu Wang, Yaochen Lv, Yanan Wang, Jiyu Liu, Xin Liu, Huanxi Zheng   +11 more
wiley   +1 more source

All‐in‐One Underwater Quality Evaluation Metamaterial With Mechanical Robustness, Sound Attenuation, and Diffuse Reflection

Advanced Science, EarlyView.
In this work, a bioinspired all‐in‐one underwater quality evaluation metamaterial, combining sound attenuation, diffuse reflection, and mechanical robustness, is proposed based on jumping spider locomotion and human skeletal biomechanics. Meanwhile, a CNN‑driven quality evaluation framework is established for theoretically dimension‐reduced ...
Hongze Li, Zhenyu Li, Jinshui Yang, Jianhao Wu, Yidan Chen, Linzhi Wu, Hong Hu, Penglin Gao, Yegao Qu   +8 more
wiley   +1 more source

The Synergism of β‐Cyclodextrin and Fe3+ Enabled Anti‐Swelling Ion‐Conductive Hydrogels for Multimodal Underwater Sensing Aided by Machine Learning Algorithms

Advanced Science, EarlyView.
An anti‐swelling ion‐conductive hydrogel is developed via β‐cyclodextrin and Fe3+ synergism, enabling reliable underwater motion sensing and Morse code communication. Integrated with machine learning, the system achieves 98.6% accuracy in real‐time underwater handwriting recognition for rapid information transmission.
Hao Dong, Chuanliu Liu, Yiming Luo, Dongyu Si, Menghan Zhao, Fangyu Zhao, Yixue Zhang, Wei Zeng, Eman Ramadan Elsharkawy, Terence Xiaoteng Liu, Zeinhom M. El‐Bahy, Hua Hou, Zhanhu Guo, Huige Wei   +13 more
wiley   +1 more source

Monolithic UV‐Laser Programming of Photothermally Meta‐Morphing SMA Structures: Dual‐Encoded Kirigami Mechanics and Photonic Absorbance

Advanced Science, EarlyView.
A monolithic manufacturing strategy is presented for photothermal shape memory alloy (SMA) meta‐morphing structures. Using a single‐step UV‐laser process, the mechanical compliance is programmed via kirigami patterning while optical absorbance is simultaneously tuned through surface oxidation.
Hyunsoo Kim, Manmatha Mahato, Hunpyo Ju, Ryanda Enggar Anugrah Ardhi, Ji‐Seok Kim, Ashhad Kamal Taseer, Myung‐Joon Lee, Hyunjoon Yoo, Il‐Kwon Oh   +8 more
wiley   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source