Eye Pain Caused by Epithelial Damage in the Central Cornea in Aqueous-Deficient Dry Eye [PDF]
In this study, the severity of eye pain (EP) and associated objective findings were evaluated in aqueous-deficient dry eye (ADDE) patients using PainVision®, a quantitative pain-measuring device.
Yamato Yoshikawa +7 more
doaj +5 more sources
Role of topical and systemic immunosuppression in aqueous-deficient dry eye disease [PDF]
Immunosuppression in aqueous-deficient dry eye disease (ADDE) is required not only to improve the symptoms and signs but also to prevent further progression of the disease and its sight-threatening sequelae.
Anahita Kate +5 more
doaj +6 more sources
Advancing Diagnostics with Semi-Automatic Tear Meniscus Central Area Measurement for Aqueous Deficient Dry Eye Discrimination [PDF]
Background and Objectives: To clinically validate a semi-automatic measurement of Tear Meniscus Central Area (TMCA) to differentiate between Non-Aqueous Deficient Dry Eye (Non-ADDE) and Aqueous Deficient Dry Eye (ADDE) patients.
Hugo Pena-Verdeal +5 more
doaj +5 more sources
Categorization of the Aqueous Deficient Dry Eye by a Cut-Off Criterion of TMH Measured with Tearscope [PDF]
A decrease of the Tear Meniscus Height (TMH) has been proposed as a useful indicator for Aqueous Deficient Dry Eye (ADDE) categorization. The present study aimed to calculate a TMH cut-off criterion for the categorization or severity assessment of ADDE ...
Belen Sabucedo-Villamarin +5 more
doaj +7 more sources
NF-κB/IL-6 axis drives impaired corneal wound healing in aqueous-deficient dry eye [PDF]
Dry eye disease (DED) commonly leads to compromised corneal epithelial integrity and chronic ocular surface inflammation; however, the precise molecular mechanisms underlying impaired corneal healing remain incompletely understood.
Cuipei Lin +20 more
doaj +5 more sources
Effect of Punctal Occlusion on Blinks in Eyes with Severe Aqueous Deficient Dry Eye [PDF]
Punctal occlusion (PO) is considered to improve both tear-film instability and increased friction during blinking and may consequently affect blinks. The purpose of this study was to investigate the effect of PO on blinks.
Hiroaki Kato +6 more
doaj +4 more sources
Aqueous-deficient dry eye disease: Preferred practice pattern guidelines on clinical approach, diagnosis, and management [PDF]
Dry eye disease (DED) is a broad term that includes a diverse group of clinical disorders. Aqueous-deficient dry eye (ADDE), a subtype of DED, is characterized by decreased tear production by the lacrimal gland.
Pragnya R Donthineni +7 more
doaj +7 more sources
Dry eye disease can be classified as aqueous-deficient, evaporative and mixed-type. Recently, neuropathic pain has been indicated to be involved in the subjective symptoms of aqueous-deficient dry eye. However, the mechanism underlying neuropathic ocular
Yoshiaki Tagawa +2 more
doaj +4 more sources
Corneal sensitivity, ocular surface health and tear film stability after punctal plug therapy of aqueous deficient dry eye [PDF]
AIM: To evaluate the effect of punctal occlusion using thermosensitive (smart plug) versus silicone plug for management of aqueous deficient dry eye on corneal sensitivity, ocular surface health and tear film stability.
Azza Mohamed Ahmed Said +4 more
doaj +3 more sources
Changes of Dry Eye Parameters Especially Meibomian Gland Functions After Punctal Plugs Insertion in Aqueous-Deficient Dry Eye Patients [PDF]
BackgroundThe study aimed at investigating the changes of dry eye parameters, especially the meibomian gland function in dry eye patients with primary Sjögren's syndrome (SS) and non-Sjögren's syndrome (non-SS) before and after punctal plugs insertion ...
Tingting Liu +5 more
doaj +5 more sources

