How Can We Best Diagnose Severity Levels of Dry Eye Disease: Current Perspectives [Corrigendum]
Chester T, Garg S, Johnston J, Ayers B, Gupta P. Clin Ophthalmol. 2023;17:1587–1604. Page 1587, author list, the text “Brandon Ayers” should read “Brandon Ayres”.
Chester T +4 more
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Thomas Kaercher,1 Ulrich Thelen,2 Gerrett Brief,3 Robert J Morgan-Warren,4 Richard Leaback41Augenarztpraxis, Heidelberg, Germany; 2University of Münster, Münster, Germany; 3Ruhr University, Bochum, Germany; 4Allergan Holdings Ltd, Marlow, UK ...
Kaercher T +4 more
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Treatment of severe dry eye following acoustic neuroma surgery with eyelid androgen gel application
Purpose: To report a case of recalcitrant dry eye disease caused by acoustic neuroma and subsequent microsurgery. Observations: A 51-year-old female presented with refractory unilateral (right eye) severe dry eye disease (DED).
Jay Ruzhang Jiang +3 more
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Peter A Simmons, Cindy Carlisle-Wilcox, Joseph G Vehige Ophthalmology Research and Development, Allergan, Inc., Irvine, CA, USA Background: Dry eye may be caused or exacerbated by deficient lipid secretion.
Simmons PA, Carlisle-Wilcox C, Vehige JG
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Presence of Histatin-1 in Human Tears and Association with Aqueous Deficient Dry Eye Diagnosis: A Preliminary Study. [PDF]
The aims of this study were to determine if histatin-1 (H1) is present in normal human tears and whether tear levels of H1 varied between normal patients and those with aqueous deficient dry eye disease (ADDE).
Kalmodia S +9 more
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Gut–ocular surface axis in dry eye disease: phenotype-specific mechanisms, evidence, and microbiome-targeted interventions [PDF]
Dry eye disease is a multifactorial, heterogeneous ocular surface disorder characterized primarily by an imbalance in tear film homeostasis. The traditional classification into “aqueous deficiency” and “evaporative” types fails to fully account for the ...
Zhizi Zhang +9 more
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Expert opinion in the management of aqueous Deficient Dry Eye Disease (DED). [PDF]
Dry eye disease (DED) affects millions of people worldwide. There are a variety of new treatments beyond traditional therapies such as preservative free artificial tears. Here, we conduct a survey to identify the most common treatments used among specialists and assess their interest in newer therapies.An international survey was distributed to dry eye
Sy A +6 more
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Association of rheumatoid arthritis with aqueous deficient dry eye development
Abstract Purpose: to evaluate rheumatoid arthritis (RA) as a potential risk factor for the development of aqueous deficient dry eye (ADDE) compared to evaporative dry eye (EDE). Study Design: The study design was observational and cross-sectional. Methods: Two hundred volunteer participants with dry eye disease (DED) were recruited based on the
Hugo Pena-Verdeal +5 more
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Management of corneal perforations in dry eye disease: Preferred practice pattern guidelines
Corneal perforations in eyes with dry eye disease (DED) are difficult to manage due to the interplay of several factors such as the unstable tear film, surface inflammation, and the underlying systemic disease affecting the wound healing process, and the
Anahita Kate +5 more
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Topical administration of lacritin is a novel therapy for aqueous-deficient dry eye disease. [PDF]
Lacritin is a tear glycoprotein with prosecretory, prosurvival, and mitogenic properties. We examined lacritin levels in the tears of Sjögren's syndrome (SS) patients and explored the therapeutic potential of topical lacritin for the treatment of keratoconjunctivitis sicca.Tears from healthy controls (n = 14) and SS patients (n = 15) were assayed for ...
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