Results 41 to 50 of about 999,360 (267)

Topical administration of lacritin is a novel therapy for aqueous-deficient dry eye disease. [PDF]

Invest Ophthalmol Vis Sci, 2014
Lacritin is a tear glycoprotein with prosecretory, prosurvival, and mitogenic properties. We examined lacritin levels in the tears of Sjögren's syndrome (SS) patients and explored the therapeutic potential of topical lacritin for the treatment of keratoconjunctivitis sicca.Tears from healthy controls (n = 14) and SS patients (n = 15) were assayed for ...
Vijmasi T, Chen FY, Balasubbu S, Gallup M, McKown RL, Laurie GW, McNamara NA.   +6 more
europepmc   +4 more sources

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Geisslinger, Gerd, Rolf M. Nusing, Gerd Geisslinger, Scholich, Klaus, Angioni, Carlo Federico, Klaus Scholich, Laura Popp, Brenneis, Christian, Ovidiu Coste, Becker, Wiebke, Popp, Laura, Nusing, Rolf M., Coste, Ovidiu, Carlo Angioni, Christian Brenneis, Ronald Schmidt, Wiebke Becker, Schmidt, Ronald   +17 more
core   +1 more source

Dose-dependent effects of Theobroma cacao in iron deficient anemia treatment in rats

Journal of Nutrition & Intermediary Metabolism, 2018
The use of herb in the treatment of diseases, including nutrient-related diseases, remains the last resort in many villages. The lack of prescription for most of these herbs may negate the undoubtful efficacy of these herbs.
Oluwasegun Modupe, Akeem Olayinka Olupo, Temidayo Adenike Oladiji   +2 more
doaj   +1 more source

Differences in meibomian fatty acid composition in patients with meibomian gland dysfunction and aqueous-deficient dry eye

, 2008
International audienceTo evaluate the differences in meibomian fatty acid composition in healthy subjects and in patients suffering from meibomian gland dysfunction or aqueous-deficient dry ...
Brétillon, Lionel, Grégoire, Stéphane, S., Creuzot-Garcher, Catherine, Viau, Sabrina, Joffre, Corinne, Acar, Niyazi, Souchier, Maxime, Creuzot Garcher, Catherine, Bron, Alain, M., Bron, Alain,, Grégoire, Stéphane,   +10 more
core   +1 more source

Nucleation Kinetics of Freeze Crystallization with Various Aqueous Solutions [PDF]

, 2023
The present work was financially supported by Finnish Foundation for Technology Promotion (Tekniikan edistämissäätiön (TES)), grant application number 8945 – year 2022.
Louhi-Kultanen, Marjatta,, Marjatta Louhi-Kultanen, Louhi-Kultanen, Marjatta, Osmanbegovic, Nahla,, Osmanbegovic, Nahla, Nahla Osmanbegovic   +5 more
core   +1 more source

Solvothermal Synthesis of Calcium Hydroxyapatite via Hydrolysis of Alpha-Tricalcium Phosphate in the Presence of Different Organic Additives

Crystals, 2023
In this study, the effects of sodium lauryl sulfate and various amino acids (DL-aspartic acid, dodecanedioic acid, and suberic acid) on the formation of calcium-deficient hydroxyapatite via hydrolysis of α-tricalcium phosphate (α-TCP) were investigated ...
Rasa Karalkeviciene, Eva Raudonyte-Svirbutaviciene, Aleksej Zarkov, Jen-Chang Yang, Anatoli I. Popov, Aivaras Kareiva   +5 more
doaj   +1 more source

Case of Congenital Deficiency of the Aqueous Humor [PDF]

The Boston Medical and Surgical Journal
n ...
openaire   +1 more source

Effect of vitamin D supplementation in aqueous deficient dry eye and evaporative dry eye in vitamin D deficient patients

Kerala Journal of Ophthalmology
Context: Dry eye disease (DED) is clinically subdivided into two types viz. aqueous deficient type and evaporative type. There are studies, which have shown that there is an association between vitamin D deficiency and dry eye disease.
Sushama N Rahate, Anukool S Deshpande, Frenali G Godhani, Rasika R Thakur   +3 more
doaj   +1 more source

Deoxyfluorination of Electron-Deficient Phenols

, 2023
In this study, we report a facile synthesis of 2-chloro-1,3-bis(2,6-diisopropylphenyl)imidazolium salts in aqueous media under ambient conditions using hypochlorite as a chlorinating agent.
Jan Jelen (12432218), Jan Jelen, Gašper Tavčar, Gašper Tavčar (1970344)   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source