Results 71 to 80 of about 999,360 (267)

All-Aqueous-Phase Microfluidics for Cell Encapsulation

, 2019
Cell-laden hydrogel microcarriers are widely used in diverse biomedical applications like three-dimensional (3D) cell culture, cellular therapy, and tissue engineering, where microcarriers were generally produced by oil, which is the common but not ...
Gang Zhao (161405), Yuanjin Zhao (1428505), Kaixuan Zhu (453857), Yunru Yu (1428514), Yue Cheng (24177), Conghui Tian (6255593)   +5 more
core   +2 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

NRF2 Deficiency Disrupts Mitochondrial Homeostasis via NDUFS7 in Trabecular Meshwork

Research
The trabecular meshwork (TM) plays a pivotal role in maintaining intraocular pressure (IOP) by regulating aqueous humor outflow. Nuclear factor erythroid 2-related factor 2 (NRF2) was identified as a key transcriptional controller of TM redox balance and
Xuejing Yan, Shen Wu, Xiaowei Fan, Qian Li, Yufei Teng, Ningli Wang, Jingxue Zhang   +6 more
doaj   +1 more source

Self-Assembly of a Purely Organic Bowl in Water via Acylhydrazone Formation

Molecules, 2023
A bowl-shaped molecule can be self-assembled by condensing a triscationic hexaaldehyde compound and three equiv. of a dihydrazide linkers in pure water.
Guangcheng Wu, Tianyu Jiao, Hao Li
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A prospective, multicenter, noninterventional study of Optive Plus® in the treatment of patients with dry eye: the prolipid study

Clinical Ophthalmology, 2014
Thomas Kaercher,1 Ulrich Thelen,2 Gerrett Brief,3 Robert J Morgan-Warren,4 Richard Leaback41Augenarztpraxis, Heidelberg, Germany; 2University of Münster, Münster, Germany; 3Ruhr University, Bochum, Germany; 4Allergan Holdings Ltd, Marlow, UK ...
Kaercher T, Thelen U, Brief G, Morgan-Warren RJ, Leaback R   +4 more
doaj  

Multiphase aqueous soggy sand electrolyte for zinc metal batteries applications at elevated temperatures

Nature Communications
Aqueous zinc metal batteries often encounter uncontrollable failure or performance decay under thermal environments, primarily due to the severe side reactions caused by aqueous electrolytes.
Jingxuan Ren, Jie Zhang, Yufeng Chen, Renming Liu, Chuangwei Liu, Xinli Guo, Dan Luo, Dongdong Wang, Zhongwei Chen   +8 more
doaj   +1 more source

Efficacy and Safety of Phospholipid Nanoemulsion-Based Ocular Lubricant for the Management of Various Subtypes of Dry Eye Disease: A Phase IV, Multicenter Trial

Clinical Ophthalmology, 2020
Elizabeth Yeu,1 Steven Silverstein,2 Michel Guillon,3 Marc-Matthias Schulze,4 David Galarreta,5 Sruthi Srinivasan,6 Venkiteshwar Manoj6 1Virginia Eye Consultants, Norfolk, VA 23502, USA; 2Silverstein Eye Centers, Kansas City, MO 64133, USA; 3Ocular ...
Yeu E, Silverstein S, Guillon M, Schulze MM, Galarreta D, Srinivasan S, Manoj V   +6 more
doaj  

Dry eye, its clinical subtypes and associated factors in healthy pregnancy: A cross-sectional study.

PLoS ONE, 2021
The study determined the frequency of dry eye, its clinical subtypes and risk factors among pregnant women. This study was a hospital-based cross-sectional study of pregnant women visiting the antenatal clinic of the University of Cape Coast hospital ...
Kofi Asiedu, Samuel Kyei, Madison Adanusa, Richard Kobina Dadzie Ephraim, Stephen Animful, Stephen Karim Ali-Baya, Belinda Akorsah, Mabel Antwiwaa Sekyere   +7 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source