Results 191 to 200 of about 48,431 (300)

Identification and Validation of Key Biomarkers in the Proximal Aqueous Humor Outflow Pathway. [PDF]

Curr Issues Mol Biol
Du R, Yang E, Clark M, Wang N, Du Y.
europepmc   +1 more source

A new three‐dimensional model to describe human corneal oxygenation during contact lenses wear

Ophthalmic and Physiological Optics, Volume 45, Issue 5, Page 1126-1141, July 2025.
Abstract Purpose This three‐dimensional study investigated how different contact lens materials affect oxygen levels in the cornea. Specifically, it measured oxygen tension, flux and consumption in the epithelium, stroma and endothelium when exposed to various contact lenses.
José M. Gozálvez‐Zafrilla, Marcel Aguilella‐Arzo, Vicente Compañ   +2 more
wiley   +1 more source

Changes in Aqueous Humor Cytokine Profile Following Intravitreal Brolucizumab Injection. [PDF]

Clin Ophthalmol
Ruamviboonsuk V, Kongwattananon W, Chuaypen N.   +2 more
europepmc   +1 more source

Lewis‐X‐Containing Triterpenoid Saponins Inhibit DC‐SIGN‐ and L‐SIGN‐Mediated Transfer of HIV‐1 Infection

Chemistry – A European Journal, Volume 31, Issue 32, June 6, 2025.
The convergent synthesis of Lewis‐X‐containing betulinic acid and echinocystic acid saponins (1 and 2) is presented. The synthetic saponins were shown to inhibit, at the low micromolar range, the DC‐SIGN‐ and L‐SIGN‐mediated transfer of HIV‐1 infection to CD4‐positive cells, whereas free Lewis‐X, aglycones, and structurally similar triterpenoid ...
Oscar Javier Gamboa Marin, Kurtis Ng, Nitish Verma, Assi Gérard Flavien Yapi, Ralph Pantophlet, Charles Gauthier   +5 more
wiley   +1 more source

A Versatile High‐Throughput Single‐Cell Screening Platform for Profiling Antigen‐Specific Long‐Lived B Cells in Blood and Bone Marrow

Advanced Science, Volume 12, Issue 21, June 5, 2025.
The MoSMAR‐chip platform provides a high‐throughput and cost‐effective tool for identifying and characterizing antigen‐specific antibody‐secreting cells (ASCs) and memory B cells (MBCs) at the single‐cell level. The ASCs from coronavirus disease 2019 (COVID‐19) vaccine‐immunized mice were successfully analyzed, revealing diverse neutralizing antibodies
Tian Zhao, Yuqing Lei, Chang Liu, Dong Zhang, Kaiyi Li, Sisi Shan, Chenyu Li, Zimeng Wei, Yuhan Yang, Ting Zhang, Kai Sun, Haoran Sun, Linqi Zhang, Peng Liu   +13 more
wiley   +1 more source

Elevated Inflammatory Cytokines Persist in the Aqueous Humor Years After Cataract Surgery. [PDF]

Invest Ophthalmol Vis Sci
Hao C, Fan E, Wei Z, Radeen KR, Purohit N, Li K, Purohit S, Fan X.   +7 more
europepmc   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, Volume 12, Issue 21, June 5, 2025.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source

Changes in aqueous humor cytokines and metabolomics in contralateral eye after unilateral cataract surgery. [PDF]

BMC Ophthalmol
Li Y, Cheng T, Zhou S, Li F, Guo W, Li M, Liu T.   +6 more
europepmc   +1 more source

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 77, Issue 6, Page 646-657, June 2025.
Objective Endogenous retroelements (EREs) stimulate type 1 interferon (IFN‐I) production but have not been explored as potential interferonogenic triggers in rheumatoid arthritis (RA). We investigated ERE expression in early RA (eRA), a period in which IFN‐I levels are increased.
Faye A. H. Cooles, Gemma Vidal Pedrola, Najib Naamane, Arthur G. Pratt, Ben Barron‐Millar, Amy E. Anderson, Catharien M. U. Hilkens, John Casement, Vincent Bondet, Darragh Duffy, Fan Zhang, Ruchi Shukla, John D. Isaacs   +12 more
wiley   +1 more source

Bioactive Compound Characterization and Phytopharmacological Potentials of Tulbaghia violacea Fruits and Seeds

Chemistry &Biodiversity, Volume 22, Issue 6, June 2025.
Flow chat for the quantitative and qualitative profiles and the biological activities of T. violacea fruits and seeds. ABSTRACT Tulbaghia violacea is an established medicinal plant that is indigenous to southern Africa. All its plant parts have been profiled for their phytochemical constituents and medicinal potentials except for the seeds and fruits ...
Rebecca Opeyemi Oyerinde, Ida Masana Risenga   +1 more
wiley   +1 more source