Results 321 to 330 of about 2,124,766 (394)

Dioxygen solubility in aqueous phosphatidylcholine dispersions

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1991
The solubility of molecular oxygen, or dioxygen, in low weight percent (1.5%) sonicated dimyristoylphosphatidylcholine (DMPC) aqueous dispersions saturated with air has been measured as a function of temperature between 10 degrees C and 40 degrees C.
E S, Smotkin, F T, Moy, W Z, Plachy
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Entacapone: Improving Aqueous Solubility, Diffusion Permeability, and Cocrystal Stability with Theophylline

Crystal Growth & Design, 2018
Cocrystallization is a well-established technique to improve the solubility, bioavailability, and stability of active pharmaceutical ingredients (APIs) but permeability and diffusion rate control via cocrystals is relatively less well studied, and the ...
M. K. Bommaka, M. K. C. Mannava, Kuthuru Suresh, Anilkumar Gunnam, A. Nangia   +4 more
semanticscholar   +1 more source

Soluble mucins in human aqueous tears

Biochemical Society Transactions, 1997
Nine mucin genes have been identified in non-ocular tissues. The many mucin gene products share a common structure with highly glycosylated variable number tandem repeat (VNTR) regions separated by naked nonVNTR regions [ 1,2]. How mucin structure relates to their function in the tear film awaits definitive characterisation of the mucins.
Ellingham, RB, Myerscough, N, Gout, II, Berry, MS, Corfield, AP   +4 more
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Solubility of Doxycycline in Aqueous Solution

Journal of Pharmaceutical Sciences, 1979
The solubility of doxycyline monohydrate and doxycycline hydrochloride dihydrate was investigated in aqueous solution. The hydrochloride dihydrate salt was isolated and identified from solutions initially containing doxycycline hyclate in water.
J B, Bogardus, R K, Blackwood
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Aqueous Solubility of 14C‐Triamcinolone Acetonide

Journal of Pharmaceutical Sciences, 1976
The blue tetrazolium colorimetric assay has often been employed in the analysis of corticosteroids. However, the reaction between blue tetrazolium and corticosteroids partly depends on the apparent pH of the system. In an earlier study of the temperature dependence of the solubility and dissolution of triamcinolone acetonide in aqueous dissolution ...
C R, Behl, L H, Block, M L, Borke
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Predicting aqueous solubility from structure

Drug Discovery Today, 2005
The aqueous solubility of a drug is one of the key physical properties that affect both its ADME profile and 'screenability' in HTS. This review critically surveys a range of methods that can be used to predict the solubility of a compound in water and presents some of the main issues that affect the applicability of different techniques.
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Recent Advances on Aqueous Solubility Prediction

Combinatorial Chemistry & High Throughput Screening, 2011
Aqueous solubility is one of the major physiochemical properties to be optimized in drug discovery. It is related to absorption and distribution in the ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity). Aqueous solubility and membrane permeability are the two key factors that affect a drug's oral bioavailability.
Junmei, Wang, Tingjun, Hou
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Aqueous solubility and true solutions.

Die Pharmazie, 2010
To the naked eye there is no sharp boundary between true solutions, where solute molecules are fully dispersed in the solvent, and colloidal solutions, where the solute molecules form very small (diameter < 50 nm) water-soluble aggregates, and smaller aggregates (diameter < 5 nm) are not easily detected by light scattering.
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High melatonin solubility in aqueous medium

Journal of Pineal Research, 1994
Shida CS, Castrucci AML, Lamy‐Freund MT. High melatonin solubility in aqueous medium. J Pineal Res. 1994:16:198–201.AbstractThe pineal hormone melatonin (5‐methoxy‐N‐acetyl‐tryptamine) has been reported to participate in important physiological processes.
C S, Shida, A M, Castrucci, M T, Lamy-Freund   +2 more
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Database for aqueous solubility of nonelectrolytes

Bioinformatics, 1989
The ARIZONA dATAbASE of Aqueous Solubility was developed. At the present time, it is the largest and most comprehensive compilation of aqueous solubility available for unionised organic compounds. The solubility data, which are extracted from various scientific articles, are objectively evaluated by five criteria: temperature, solute purity ...
R, Dannenfelser, S H, Yalkowsky
openaire   +2 more sources