Results 21 to 30 of about 581,287 (268)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Simultaneous Spectrophotometric Determination of o-Aminophenol and p-Aminophenol Using H-Point Standard Addition Method -Application to Real Waters [PDF]

Pakistan Journal of Analytical & Environmental Chemistry, 2012
H-point standard addition method (HPSAM) has been applied to the simultaneous determination of o-aminophenol (oA) and p-aminophenol (pA) isomers in binary mixtures.
Theia'a N. Al-Sabha, Nagham N. Habeb
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Spectrophotometric Determination of Aminophenol Isomers in Aqueous Solution using 1,2-Naphthoquinone-4-sulphonate Reagent [PDF]

Pakistan Journal of Analytical & Environmental Chemistry, 2011
A spectrophotometric method was developed for the quantitative determination of aminophenol isomers. The method is based on their reaction with 1,2-Naphthoquinone-4-sulphonate (NQS) reagent in aqueous basic medium forming colored products with maximum ...
T. N. Al-Sabha, N. N. Habeb
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Adsorption of mercury (II) from liquid solutions using modified activated carbons

Materials Research, 2010
Mercury is one of the most toxic metals present in the environment. Adsorption has been proposed among the technologies for mercury abatement. Activated carbons are universal adsorbents which have been found to be a very effective alternative for mercury
Hugo Soé Silva, Silvia Virginia Ruiz, Dolly Lucía Granados, Juan Manuel Santángelo   +3 more
doaj   +1 more source

Synthesis of Calcium Silicate Hydrate from Coal Gangue for Cr(VI) and Cu(II) Removal from Aqueous Solution

Molecules, 2021
Both the accumulation of coal gangue and potentially toxic elements in aqueous solution have caused biological damage to the surrounding ecosystem of the Huainan coal mining field.
Qing Zhang, Guijian Liu, Shuchuan Peng, Chuncai Zhou   +3 more
doaj   +1 more source

Sonophotoluminescence from aqueous and non-aqueous solutions

Ultrasonics Sonochemistry, 1999
The sonoluminescence generated in air-saturated aqueous and non-aqueous solutions using 515 kHz ultrasound has been used to vibronically excite several fluorescent solutes, namely fluorescein, eosin, pyranine and pyrene. Emission, referred to as 'sonophotoluminescence', was generated in situ with emission spectra that closely matched those obtained by ...
M, Ashokkumar, F, Grieser
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source