Results 51 to 60 of about 1,475,589 (309)

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Removal Methods of Antibiotic Compounds from Aqueous Environments– A Review

open access: yesJournal of Environmental Health and Sustainable Development, 2016
Introduction: Antibiotics as a type of pharmaceutical compounds are widely used in modern medicine and veterinary industries. They enter the environment in different ways, including agricultural runoff, direct discharge of urban wastewater treatment or ...
Zahra Derakhshan   +5 more
doaj  

Ultrathin triphenylamine–perylene diimide polymer with D–A structure for photocatalytic oxidation of N‐heterocycles using ambient air

open access: yesEcoMat, 2022
An ultrathin porous triphenylamine–perylene diimide (PDI) polymer photocatalyst with photooxidative ability was prepared. Triphenylamine–PDI oxidizes 1,2,3,4‐tetrahydroisoquinoline to 3,4‐dihydroisoquinoline with a yield of 84% and selectivity of 92 ...
Hanjie Zhang   +3 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Snow-Ice-Inspired Approach for Growth of Amorphous Silicon Nanotips

open access: yesNanomaterials, 2019
The growth of one-dimensional nanostructures without a metal catalyst via a simple solution method is of considerable interest due to its practical applications.
Seungil Jo, Hyunsoo Kim, Nae-Man Park
doaj   +1 more source

The Use of Plasmonic Spectroscopy for Detecting Ultra-Low Concentrations of Substances

open access: yesPhotonics, 2022
This paper presents the results of research into the excitation of a surface electromagnetic wave (SEW) in Au/AgI and Au/Ag films contacting aqueous solutions of hydrogen peroxide (H2O2) and sodium chloride (NaCl).
Michael Kononov   +3 more
doaj   +1 more source

Oxygen-hydrogen fuel cell with an iodine-iodide cathode - A concept [PDF]

open access: yes, 1970
Fuel cell uses a porous cathode through which is fed a solution of iodine in aqueous iodide solution, the anode is a hydrogen electrode. No activation polarization appears on the cathode because of the high exchange-current density of the iodine-iodide ...
Javet, P.
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Electrophotolysis oxidation system for measurement of organic concentration in water [PDF]

open access: yes, 1981
Methods and apparatus for determining organic carbon in aqueous solution are described. The method comprises subjecting the aqueous solution to electrolysis, for generating oxygen from water, and simultaneously to ultraviolet radiation, for oxidation of ...
Winkler, H. E.
core   +1 more source

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