Results 101 to 110 of about 8,277,314 (334)
Cell Death and Disease, 2017 Hepatocellular carcinoma (HCC) is a heterogeneous malignancy as a result of complex genetic and epigenetic alterations. HCC is characterized by a clear gender disparity for which there is lack of a clear mechanistic understanding.
Liang Shi +8 more
semanticscholar +1 more source
Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer [PDF]
, 2017 1.7 million cases of breast cancer are diagnosed every year with 522,000 deaths. Molecular classifications of breast cancer have resulted in improved treatments. However, treatments for triple negative breast cancer (TNBC) are lacking.
Edwards, Joanne +6 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Depth from motion for smartphone AR
ACM Transactions on Graphics, 2018 Augmented reality (AR) for smartphones has matured from a technology for earlier adopters, available only on select high-end phones, to one that is truly available to the general public.
Julien P. C. Valentin +20 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Special Section Preface: Informative Models and Systems for Virtual Museums
Virtual Archaeology Review, 2019 Special Section ...
R. Brumana, G. Tucci, J.L. Lerma
doaj +1 more source
Double Andreev Reflections in Type-II Weyl Semimetal-Superconductor Junctions
, 2017 We study the Andreev reflections (ARs) at the interface of the type-II Weyl semimetal-superconductor junctions and find double ARs when the superconductor is put in the Weyl semimetal band tilting direction, which is similar to the double reflections of ...
Hou, Zhe, Sun, Qing-Feng
core +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Asymptotic inference for nearly unstable AR(p) processes [PDF]
, 1999 In this paper nearly unstable AR( p) processes (in other words, models with characteristic roots near the unit circle) are studied. Our main aim is to describe the asymptotic behavior of the least-squares estimators of the coefficients.
Pap, Gyula +2 more
core +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source