Results 51 to 60 of about 276,580 (352)

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Genome-wide analysis of local chromatin packing in Arabidopsis thaliana

Genome Research, 2015
The spatial arrangement of interphase chromosomes in the nucleus is important for gene expression and genome function in animals and in plants. The recently developed Hi-C technology is an efficacious method to investigate genome packing. Here we present
Congmao Wang, Chang Liu, D. Roqueiro, D. Grimm, R. Schwab, C. Becker, C. Lanz, D. Weigel   +7 more
semanticscholar   +1 more source

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

Advanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao, Xiaolong Wang, Langchen Guo, Lijun Xiang, Enxi Luo, Peng Cao, Penghui Liu, Yue Zhong, Chun Li, Jun Lai, Jun Yang, Shouchuang Wang   +11 more
wiley   +1 more source

High-throughput single-cell transcriptomics reveals the female germline differentiation trajectory in Arabidopsis thaliana

Communications Biology, 2021
Zhimin Hou, Yanhui Liu et al. used single cell RNA-seq to analyze the model organism, Arabidopsis thaliana, at three stages during female germline differentiation. They reconstructed the continuous trajectory of female germline differentiation, providing
Zhimin Hou, Yanhui Liu, Man Zhang, Lihua Zhao, Xingyue Jin, Liping Liu, Zhenxia Su, Hanyang Cai, Yuan Qin   +8 more
doaj   +1 more source

GbSER02 Interacts With GhVOZ1 to Promote Fiber Elongation by Modulating Gibberellin Synthesis in Cotton

Advanced Science, EarlyView.
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia, Dongmei Zhang, Qishen Gu, Yanbin Li, Jing Li, Wannian Li, Zhengwen Sun, Huifeng Ke, Jun Yang, Liqiang Wu, Yan Zhang, Zhiying Ma, Xingfen Wang   +12 more
wiley   +1 more source

Study the Effect of Arabidopsis thaliana Extract on Reducing Blood Glucose Level in Diabetic White Albino Mice

Iraqi Journal of Pharmaceutical Sciences, 2017
This study was designed to evaluate the effect of aqueous extract of Arabidopsis thaliana seeds on reducing glucose level for white albino mice. Twenty adults mice were used, divided randomly into four groups (five mice per each group).
Khaleel I. Rashid, Abedaljasim M. Aljibouri, AbdulAmeer J. Zayer, Luma B. Khalid, Ahmed Abdul-Munaem   +4 more
doaj   +3 more sources

Physiological role of brassinolide in the light development of Arabidopsis thaliana seedling

RUDN Journal of Agronomy and Animal Industries, 2011
The regulatory role of more active brassinosteroids - brassinolide in seedling development in darkness was studied. The growth parameters and photosynthetic pigment content of Arabidopsis thaliana seedlings under differ light conditions were investigated.
M V Efimova
doaj  

Comparative structural analysis of HAC1 in Arabidopsis thaliana [PDF]

Network Biology, 2014
Histone acetylation is an important posttranslational modification correlated with gene activation. In Arabidopsis thaliana, the histone acetyltransferase 1 (AtHAC1) is homologous to animal p300/CREB (cAMPresponsive element-binding protein)-binding ...
Amar Cemanovic, Jasmin Sutkovic, Mohamed Ragab Abdel Gawwad   +2 more
doaj  

Arabidopsis thaliana Cells: A Model to Evaluate the Virulence of Pectobacterium carotovorum

Molecular Plant-Microbe Interactions, 2010
Pectobacterium carotovorum are economically important plant pathogens that cause plant soft rot. These enterobacteria display high diversity world-wide.
Meriam Terta, Mohamed Kettani-Halabi, Khadija Ibenyassine, Daniel Tran, Patrice Meimoun, Raja Ait M'hand, Hayat El-Maarouf-Bouteau, Florence Val, M. Mustapha Ennaji, François Bouteau   +9 more
doaj   +1 more source