Results 1 to 10 of about 16,669 (96)
Cytosine Arabinoside-Induced Vasculitis [PDF]
Mayo Clinic Proceedings, 1998 Dermatologic side effects of cytosine arabinoside (ara-C) are rare and most commonly occur after high-dose (more than 100 to 200 mg/m2 per day) therapy has been administered for several days. Although vascular reactions after combination chemotherapeutic regimens with ara-C have been anecdotally described, they have not been previously reported after ...
I, Ahmed +3 more
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Combined Antiviral Effects of Interferon, Adenine Arabinoside, Hypoxanthine Arabinoside, and Adenine Arabinoside-5′-Monophosphate in Human Fibroblast Cultures [PDF]
Antimicrobial Agents and Chemotherapy, 1977 Adenine arabinoside and human interferon are currently being evaluated in clinical trials against herpes- and poxvirus infections. Interferon production is also a normal antiviral response. It is therefore important to examine the combined actions of interferon and antiviral arabinosides for possible synergy or antagonism.
Y J, Bryson, L H, Kronenberg
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A radioimmunoassay for cytosine arabinoside [PDF]
British Journal of Cancer, 1979 A radioimmunoassay (RIA) for cytosine arabinoside (AraC) has been developed using antiserum raised in a sheep to an AraC monophosphate-ovalbumin conjugate. The antibody shows only 0.008% cross-reactivity with uracil arabinoside (AraU) and low (0.023%) cross-reactivity with other commonly co-administered drugs such as cytotoxic and antibacterial agents,
E M, Piall, G W, Aherne, V M, Marks
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Simple Sensitive Microbioassay for Adenine Arabinoside and Hypoxanthine Arabinoside in Human Plasma [PDF]
Antimicrobial Agents and Chemotherapy, 1978 Previous methods using low- or high-pressure liquid chromatography and UV absorbance for quantitation of arabinosides in plasma can practically detect only ≥200 ng of adenine arabinoside and ≥100 ng of hypoxanthine arabinoside per ml, and they require expensive equipment and expert technical assistance.
Y J, Bryson, L, Sweetman, J D, Connor
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Paraplegia following intrathecal cytosine arabinoside [PDF]
Cancer, 1979 Paraplegia following prophylactic intrathecal cytosine arabinoside (Ara-C) is described in a patient with acute myelogenous leukemia in remission who received doses of 100 mg/m2/d for 5 consecutive days. Cerebrospinal fluid examination prior to the last dosage of cytosine arabinoside revealed a mononuclear pleocytosis and increased protein.
L, Wolff, J, Zighelboim, R P, Gale
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Hypoxanthine-arabinoside pharmacokinetics after adenine arabinoside administration to a patient with renal failure [PDF]
Antimicrobial Agents and Chemotherapy, 1980 Hypoxanthine arabinoside pharmacokinetics were measured during an adenine arabinoside continuous intravenous infusion and during hemodialysis in a patient with renal failure. Therapeutic guidelines for adenine arabinoside in renal failure are provided based on an elimination half-life of 4.7 h and a plasma clearance of 87.9 ml/min for the hypoxanthine ...
G R, Aronoff +4 more
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In Vitro Susceptibility of Varicella Zoster Virus to Adenine Arabinoside and Hypoxanthine Arabinoside [PDF]
Antimicrobial Agents and Chemotherapy, 1976 The in vitro susceptibility of varicella zoster (VZ) isolates to adenine arabinoside (ara-A) and hypoxanthine arabinoside (ara-Hx) was determined in human skin fibroblasts. Using a system in which deamination was inhibited, and using a modified plaque reduction method, the antiviral activities of ara-A and ara-Hx were separated.
Y J, Bryson, J D, Connor
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Ineffectiveness of adenine arabinoside and adenine arabinoside 5'-monophosphate in simian varicella infection [PDF]
Antimicrobial Agents and Chemotherapy, 1980 Adenine arabinoside and adenine arabinoside 5'-monophosphate (ara-AMP) have been evaluated for antiviral activity against simian varicella virus infection in monkeys. In a preliminary study for toxicity, intramuscular injection of ara-AMP at 15 mg/kg per day as a single injection for 5 days to two normal patas monkeys caused no detectable local ...
K F, Soike +3 more
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Hydroxyproline Arabinosides in the Plant Kingdom [PDF]
Plant Physiology, 1971 The hydroxyproline-O-arabinosyl linkage is present in cell walls of selected tissues representing green plants from algae to angiosperms.
D T, Lamport, D H, Miller
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