Results 31 to 40 of about 27,903 (211)

A N-(4-chlorophenyl)-γ-amino acid derivatives exerts in vitro anticancer activity on non-small cell lung carcinoma cells and enhances citosine arabinoside (AraC)-induced cell death via mitochondria-targeted pathway

Results in Chemistry, 2021
A Non-Small Cell Lung Cancer (NSCLC) is among the leading cause of cancer-associated morbidity and mortality worldwide. Novel treatment and drug repurposing strategies are needed.
Povilas Kavaliauskas, Šarūnas Žukauskas, Kazimieras Anusevičius, Benas Balandis, Rita Vaickelionienė, Vidmantas Petraitis, Vytautas Mickevičius   +6 more
doaj   +1 more source

Anthocyanin absorption and metabolism by human intestinal Caco-2 cells: a review [PDF]

, 2015
Anthocyanins from different plant sources have been shown to possess health beneficial effects against a number of chronic diseases. To obtain any influence in a specific tissue or organ, these bioactive compounds must be bioavailable, i.e., effectively ...
Battino, Maurizioeditor, Capanoglu, Esra, Grootaert, CharlotteLA23002000065127801001998257F7A30E30-F0ED-11E1-A9DE-61C894A0A6B4, Kamiloglu, SenemUGent0001303221268020017844329746706457840000-0003-3902-4360553D4B12-2C77-11E3-8FFE-9F6610BDE39D, Van Camp, JohnLA238010009006420000-0002-6468-6107F4B233EA-F0ED-11E1-A9DE-61C894A0A6B4   +4 more
core   +3 more sources

Cytosine arabinoside exposure induced cytotoxic effects and neural tube defects in mice and embryo stem cells

Ecotoxicology and Environmental Safety, 2023
Cytosine arabinoside (Ara-C) is one of the most widely used chemotherapeutic agents for hematological malignancies. The residues of Ara-C have been detected in wastewater and river water with increased usage and discharge.
Zhen Guan, Yingchao Liang, Zhiqiang Zhu, Aiyun Yang, Shen Li, Jin Guo, Fang Wang, Huimin Yang, Na Zhang, Xiuwei Wang, Jianhua Wang   +10 more
doaj   +1 more source

Treatment of the elderly patient with acute myeloid leukaemia [PDF]

, 1996
The antiviral and cytotoxic effects of ara-arabinoside monophosphate, 2′,3′, dideoxy-cytidine, ganciclovir, 9-2(-phosphonylmethoxyethyl) adenine, 2′,3′-dideoxy-3′-thiacytidine and recombinant interferon-alpha were studied using two human hepatitis B ...
Löwenberg, B. (Bob)
core   +10 more sources

Trypanosoma brucei methylthioadenosine phosphorylase protects the parasite from the antitrypanosomal effect of deoxyadenosine [PDF]

, 2016
Trypanosoma brucei causes African sleeping sickness for which no vaccine exists and available treatments are of limited use due to their high toxicity or lack of efficacy. T.
de Koning, Harry P., Hofer, Anders, Pavlova, Anna, Ranjbarian, Farahnaz, Vodnala, Munender   +4 more
core   +1 more source

Off-Label Use of Crisdesalazine (GedaCure) in Meningoencephalitis in Two Dogs

Veterinary Sciences, 2023
An 8-year-old, castrated male Shih-tzu dog (Case 1) showing ataxia and gait disorder was referred for neurological examination and magnetic resonance imaging.
Saeyoung Lee, Woo-Jin Song, Jongjin Park, Minkun Kim, Sangkyung Choen, Myung-Chul Kim, Hyohoon Jeong, Youngmin Yun   +7 more
doaj   +1 more source

Research of Cranberry Main Indicators of Chemical Composition and Its Processing Products [PDF]

, 2017
It is well–known that cranberry is an especially rich and heterogenic source of phytochemical substances. Modern technologies allow to produce food products of wild fruits and berries, but they use their diverse and useful chemical composition ...
Khomych, G. (Galyna), Matsuk, Y. (Yuliiа), Medved, L. (Lolita), Nakonechnaya, J. (Julia), Oliynyk, N. (Nataliа)   +4 more
core   +2 more sources

The boundary cap: a source of neural crest stem cells that generate multiple sensory neuron subtypes [PDF]

, 2005
The boundary cap (BC) is a transient neural crest-derived group of cells located at the dorsal root entry zone (DREZ) that have been shown to differentiate into sensory neurons and glia in vivo.
Cederberg, A, Enerback, S, Ernfors, P, Heglind, M, Hjerling-Leffler, J, Koltzenburg, M, Marmigere, F   +6 more
core   +2 more sources

Clonal karyotype evolution involving ring chromosome 1 with myelodysplastic syndrome subtype RAEB-t progressing into acute leukemia [PDF]

, 2006
s Karyotypic evolution is a well-known phenomenon in patients with malignant hernatological disorders during disease progression. We describe a 50-year-old male patient who had originally presented with pancytopenia in October 1992.
Bennett JM, Bettina Wunderlich, Brigitte Poleck-Dehlin, Chen Z, Christoph Schmid, Cutler CS, De Witte T, Depil S, Georg Ledderose, Gisselsson D, Gullingsrud EO, Hans Jochen Kolb, Hebart H, Helga Schmetzer, Hoffmann WK, Hoffmeister PA, Holler E, Johann Mittermüller, Johansson B, Jotterand M, Kern W, Kolb HJ, Kolb HJ, Massenkeil G, Mattano, Mhawesch P, Mittermuller J, Moss PA, Mufti GJ, Rothe G, Sanders JE, Schmetzer H, Schmetzer H, Schmetzer HM, Schmid C, Seabright M, Seber A, Slovak ML, Sole F, Sole F, Thomas Duell, Tichelli A, Tichelli A, van Esser JW, Xu J, Yan J, Yoshida A   +46 more
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The combination of methotrexate and cytosine arabinoside in newly diagnosed adult Langerhans cell histiocytosis: a prospective phase II interventional clinical trial

BMC Cancer, 2020
Background Langerhans Cell Histiocytosis (LCH) is a rare disease puzzling both children and adults, however outcome of adult patients is unfavorable.
Xiao Han, Mingqi Ouyang, Minghui Duan, Wei Zhang, Tienan Zhu, Jian Li, Shujie Wang, Daobin Zhou   +7 more
doaj   +1 more source