Results 51 to 60 of about 27,903 (211)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Anthocyanins and Flavonoids of Vaccinium L. [PDF]

, 2012
Vaccinium L., comprising approximately 450 species primarily in the Northern Hemisphere, is a genus of shrubs or lianas in the family Ericaceae. The berries of many species are harvested for household consumption and commercial sale. The genus produces a
Su, Zushang
core   +2 more sources

Isolation and Purification of Schwann Cells from Spinal Nerves of Neonatal Rat

Bio-Protocol, 2017
Primary cultured Schwann cells (SCs) are widely used in the investigation of the biology of SC and are important seed cells for neural tissue engineering. Here, we describe a novel protocol for harvesting primary cultured SCs from neonatal Sprague-Dawley
Jinkun Wen, Dandan Tan, Lixia Li, Jiasong Guo   +3 more
doaj   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Gender effects on cytidine analogue metabolism and myelodysplastic syndrome treatment outcomes [PDF]

, 2012
In vivo, half-lives of cytidine analogues such as 5-azacytidine and decitabine, used to treat myelodysplastic syndromes (MDS), are determined largely by cytidine deaminase (CDA), an enzyme that rapidly metabolizes these drugs into inactive uridine ...
Ania Jankowska, Jaroslaw Maciejewski, Joseph Covey, Kenneth Chan, Kory Engelke, Mikkael Sekeres, Pramod Terse, Quteba Ebrahem, Ramon Tiu, Reda Mahfouz, Tomas Radivoyevitch, Yogen Saunthararajah, Yonghua Ling, Zhenbo Hu   +13 more
core   +1 more source

Investigation of acetyl migrations in furanosides

Beilstein Journal of Organic Chemistry, 2006
Standard reaction conditions for the desilylation of acetylated furanoside (riboside, arabinoside and xyloside) derivatives facilitate acyl migration.
O. P. Chevallier, M. E. Migaud
doaj   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

Acute Respiratory Distress Syndrome Associated with Tumour Lysis Syndrome in Leukemia

Canadian Respiratory Journal, 1997
Acute tumour lysis syndrome (ATLS) developed in two patients with acute myelogenous leukemia soon after they were treated with cytosine arabinoside. The patients also developed respiratory distress requiring intubation.
Chaim M Bell, Thomas E Stewart
doaj   +1 more source

Phytogenotypic Anthocyanin Profiles and Antioxidant Activity Variation in Fruit Samples of the American Cranberry (Vaccinium macrocarpon Aiton)

Antioxidants, 2022
In this study, we conducted an analysis of the qualitative and quantitative composition of anthocyanins and anthocyanidins in different cultivars and genetic clones of American cranberries grown in Lithuanian climatic conditions.
Rima Urbstaite, Lina Raudone, Valdimaras Janulis   +2 more
doaj   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source