Results 91 to 100 of about 9,418 (167)

Arachnoid cyst of the middle fossa complicated by spontaneous subdural hematoma and intracranial hypertension: Case report

open access: yesInterdisciplinary Neurosurgery
Introduction: Chronic subdural hematomas (CSDH) are common problems in neurosurgery, generally secondary to head trauma, although they me be in rare cases associated to underlying pathologies.
William W. Lines-Aguilar   +7 more
doaj   +1 more source

Context‐dependent TREM2 signalling in myeloid cells: Molecular mechanisms and immunotherapeutic divergence in neurodegeneration and cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 10, October 2026.
Divergent triggering receptor expressed on myeloid cells 2 (TREM2) signalling pathways instruct myeloid cell adaptation towards neuroprotective disease‐associated microglia (DAM)/lipid‐associated macrophage (LAM) or immunosuppressive tumour‐associated macrophage (TAM) phenotypes.
Yaqing Lv   +5 more
wiley   +1 more source

Astrocyte subtype‐specific alterations in the dentate gyrus of individuals with mesial temporal lobe epilepsy

open access: yesEpilepsia Open, Volume 11, Issue 5, Page 1651-1667, October 2026.
Abstract Objective Epilepsy affects approximately 50 million people worldwide and, although primarily attributed to neuronal dysfunction, increasing evidence highlights a critical role of glial cells, particularly astrocytes, in the pathophysiological mechanisms.
Chiara Lötzsch   +5 more
wiley   +1 more source

Orbitofrontal and Medial Frontal Gray Matter Volumes Are Associated With Hyperactivity Traits in 2548 Nonclinical Adults

open access: yesHuman Brain Mapping, Volume 47, Issue 14, October 1, 2026.
In 2548 nonclinical adults, smaller orbitofrontal and medial frontal cortex gray matter volumes were associated with higher hyperactivity traits (r = −0.07 to −0.08). These small, robust effects, consistent with ENIGMA ADHD findings, suggest frontal structure–trait mapping extends to the nonclinical ADHD continuum.
Handityo Aulia Putra, Kaechang Park
wiley   +1 more source

Senescent Cell‐Derived Extracellular Vesicles in Therapy‐Induced Senescence: Immune Remodelling and Emerging Links to Mitochondrial Stress in Cancer

open access: yesJournal of Extracellular Biology, Volume 5, Issue 10, October 2026.
ABSTRACT Cancer therapy can induce cellular senescence and remodel the tumour microenvironment through the senescence‐associated secretory phenotype (SASP), including its membrane‐enclosed component, senescent cell‐derived extracellular vesicles (senEVs). This review summarizes senEV biogenesis, cargo‐dependent functions, and immune‐remodelling effects
Yongrui Qian   +4 more
wiley   +1 more source

Intracranial arachnoid cyst without common clinical symptoms in a 10 years old child: A case report

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2018
Arachnoid cysts have primary and secondary types. The prevalence of Arachnoid cysts is about 1% of all tumors in cranial cavity. Based on anatomic position, arachnoid cyst can cause different clinical manifestations including hemiparesis, increase ...
Seyyed Ahmad Hoseini   +5 more
doaj  

Obstruction caused by suprasellar cisterna arachnoid cyst expansion after ventriculoperitoneal shunt in children with hydrocephalus

open access: yesPediatric Investigation
Introduction Suprasellar cistern arachnoid cysts are rare non‐neoplastic cystic lesions that represent nearly 1% of all intracranial arachnoid cysts. Symptomatology can vary; small cysts typically do not produce any symptoms, whereas larger cysts may ...
Dapeng Li, Wenping Ma, Ming Ge, Di Zhang
doaj   +1 more source

Gut Microbiome Diversity, Functional Potential, and Ecological Relevance of Hottentotta tamulus

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Long‐read 16S sequencing uncovers the gut microbiome of H. tamulus. A highly conserved and low‐diversity bacterial community dominates the gut fauna. Bacillus and Mycoplasma lineages emerge as predominant candidate endosymbionts. Exploratory profiles reveal potential sex‐specific trends in microbial abundance.
Khajid Ullah Khan   +8 more
wiley   +1 more source

EEF1D‐Associated Neurodevelopmental Disorders: Evidence From Iranian Siblings With a Biallelic Splice Junction Loss Variant

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
We identified a novel homozygous variant (c.1489‐26_1493del) in EEF1D in an Iranian sibling with global developmental delay, intellectual disability, microcephaly, and failure to thrive. This likely pathogenic variant, absent in gnomAD v4, further supports EEF1D as a causative gene for autosomal recessive neurodevelopmental disorders, reinforcing ...
Maedeh Ganji   +9 more
wiley   +1 more source

Prenatal exome sequencing of fetuses with central nervous system anomalies based on prenatal ultrasound and magnetic resonance imaging diagnosis: A retrospective cohort study with a systematic review and meta‐analysis

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 1950-1964, October 2026.
Prenatal exome sequencing significantly improves diagnostic yield over chromosomal microarray analysis for fetal CNS abnormalities, with a diagnostic yield of 16% in our cohort and 27% in the meta‐analysis. Diagnostic yields vary across different phenotypes. Abstract Introduction Fetal central nervous system (CNS) abnormalities have diverse etiologies,
Jia Yao   +5 more
wiley   +1 more source

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