Results 41 to 50 of about 28,012 (240)

NS1 Protein N-Linked Glycosylation Site Affects the Virulence and Pathogenesis of Dengue Virus

open access: yesVaccines, 2023
Live attenuated vaccine is one of the most effective vaccines against flavivirus. Recently, site-directed mutation of the flavivirus genome using reverse genetics techniques has been used for the rapid development of attenuated vaccines.
Enyue Fang   +8 more
doaj   +1 more source

Review of Importance of Weather and Environmental Variables in Agent-Based Arbovirus Models

open access: yesInternational Journal of Environmental Research and Public Health, 2022
The study sought to review the works of literature on agent-based modeling and the influence of climatic and environmental factors on disease outbreak, transmission, and surveillance.
Luba Pascoe   +3 more
semanticscholar   +1 more source

Globe-Trotting Aedes aegypti and Aedes albopictus: Risk Factors for Arbovirus Pandemics

open access: yesVector Borne and Zoonotic Diseases, 2020
Introduction: Two species of Aedes (Ae.) mosquitoes (Ae. aegypti and Ae. albopictus) are primary vectors for emerging arboviruses that are a significant threat to public health and economic burden worldwide.
O. Lwande   +6 more
semanticscholar   +1 more source

Immune response to arbovirus infection in obesity

open access: yesFrontiers in Immunology, 2022
Obesity is a global health problem that affects 650 million people worldwide and leads to diverse changes in host immunity. Individuals with obesity experience an increase in the size and the number of adipocytes, which function as an endocrine organ and
Muddassar Hameed   +4 more
semanticscholar   +1 more source

Targeting Host PIM Protein Kinases Reduces Mayaro Virus Replication

open access: yesViruses, 2022
Mayaro virus (MAYV) manipulates cell machinery to successfully replicate. Thus, identifying host proteins implicated in MAYV replication represents an opportunity to discover potential antiviral targets.
Madelaine Sugasti-Salazar   +4 more
doaj   +1 more source

Enhanced Arbovirus Surveillance with High-Throughput Metatranscriptomic Processing of Field-Collected Mosquitoes

open access: yesViruses, 2022
Surveillance programs are essential for the prevention and control of mosquito-borne arboviruses that cause serious human and animal diseases. Viral metatranscriptomic sequencing can enhance surveillance by enabling untargeted, high-throughput arbovirus ...
J. Batovska   +4 more
semanticscholar   +1 more source

The global distribution of the arbovirus vectors Aedes aegypti and Ae. albopictus

open access: yeseLife, 2015
Dengue and chikungunya are increasing global public health concerns due to their rapid geographical spread and increasing disease burden. Knowledge of the contemporary distribution of their shared vectors, Aedes aegypti and Aedes albopictus remains ...
Moritz U. G. Kraemer   +21 more
semanticscholar   +1 more source

An Updated Review of the Invasive Aedes albopictus in the Americas; Geographical Distribution, Host Feeding Patterns, Arbovirus Infection, and the Potential for Vertical Transmission of Dengue Virus

open access: yesInsects, 2021
Simple Summary Currently, the Asian tiger mosquito Aedes albopictus Skuse is present on all continents except Antarctica. Efficiency as a vector of Ae. albopictus is different by geographic region.
J. García-Rejón   +3 more
semanticscholar   +1 more source

Broad Antiviral Activity of Ginkgolic Acid against Chikungunya, Mayaro, Una, and Zika Viruses

open access: yesViruses, 2020
The alphaviruses Chikungunya (CHIKV), Mayaro (MAYV), Una (UNAV), and the flavivirus Zika (ZIKV) are emerging or re-emerging arboviruses which are responsible for frequent epidemic outbreaks. Despite the large impact of these arboviruses on health systems,
Dalkiria Campos   +4 more
doaj   +1 more source

Inhibition of p38 Mitogen-Activated Protein Kinase Impairs Mayaro Virus Replication in Human Dermal Fibroblasts and HeLa Cells

open access: yesViruses, 2021
Mayaro virus (MAYV) hijacks the host’s cell machinery to effectively replicate. The mitogen-activated protein kinases (MAPKs) p38, JNK, and ERK1/2 have emerged as crucial cellular factors implicated in different stages of the viral cycle.
Madelaine Sugasti-Salazar   +3 more
doaj   +1 more source

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