Results 31 to 40 of about 24,859 (181)

Targeting Host PIM Protein Kinases Reduces Mayaro Virus Replication

Viruses, 2022
Mayaro virus (MAYV) manipulates cell machinery to successfully replicate. Thus, identifying host proteins implicated in MAYV replication represents an opportunity to discover potential antiviral targets.
Madelaine Sugasti-Salazar, Dalkiria Campos, Patricia Valdés-Torres, Paola Elaine Galán-Jurado, José González-Santamaría   +4 more
doaj   +1 more source

Climate Variability and Ross River Virus Transmission in Townsville Region, Australia 1985 to 1996 [PDF]

, 2004
Background How climate variability affects the transmission of infectious diseases at a regional level remains unclear. In this paper, we assessed the impact of climate variation on the Ross River virus (RRv) transmission in the Townsville region ...
A. J. McMichael, Aaskov JG, Allard R, Australian Bureau of Statistics, Bowie C, Catalano R, Chatfield C, Checkley W, Curran M, Curriero FC, Doherty RL, Helfenstein U, Helfenstein U, Helfenstein U, Hennessy KJ, Kay BH, Liehne PF, Lindsay M, Lindsay MD, Lindsay MD, Mackenzie JS, McManus TJ, McMichael AJ, Nimmol JR, Russell RC, Shilu Tong, Shope RE, Tabachnick BG, Tong SL, Weinstein P, Wenbiao Hu, Whetton P   +31 more
core   +2 more sources

Inhibition of p38 Mitogen-Activated Protein Kinase Impairs Mayaro Virus Replication in Human Dermal Fibroblasts and HeLa Cells

Viruses, 2021
Mayaro virus (MAYV) hijacks the host’s cell machinery to effectively replicate. The mitogen-activated protein kinases (MAPKs) p38, JNK, and ERK1/2 have emerged as crucial cellular factors implicated in different stages of the viral cycle.
Madelaine Sugasti-Salazar, Yessica Y. Llamas-González, Dalkiria Campos, José González-Santamaría   +3 more
doaj   +1 more source

Wolbachia and arbovirus inhibition in mosquitoes [PDF]

, 2013
Wolbachia is a maternally inherited intracellular bacteria that can manipulate the reproduction of their insect hosts, and cytoplasmic incompatibility allows them to spread through mosquito populations.
Sinkins, Steven P.
core   +1 more source

Trends of the Dengue Serotype-4 Circulation with Epidemiological, Phylogenetic, and Entomological Insights in Lao PDR between 2015 and 2019

Pathogens, 2020
Dengue outbreaks have regularly been recorded in Lao People’s Democratic Republic (PDR) since the first detection of the disease in 1979. In 2012, an integrated arbovirus surveillance network was set up in Lao PDR and an entomological surveillance has ...
Elodie Calvez, Virginie Pommelet, Somphavanh Somlor, Julien Pompon, Souksakhone Viengphouthong, Phaithong Bounmany, Thep Aksone Chindavong, Thonglakhone Xaybounsou, Phoyphaylinh Prasayasith, Sitsana Keosenhom, Paul T. Brey, Olivier Telle, Marc Choisy, Sébastien Marcombe, Marc Grandadam   +14 more
doaj   +1 more source

Broad Antiviral Activity of Ginkgolic Acid against Chikungunya, Mayaro, Una, and Zika Viruses

Viruses, 2020
The alphaviruses Chikungunya (CHIKV), Mayaro (MAYV), Una (UNAV), and the flavivirus Zika (ZIKV) are emerging or re-emerging arboviruses which are responsible for frequent epidemic outbreaks. Despite the large impact of these arboviruses on health systems,
Dalkiria Campos, Susana Navarro, Yessica Yadira Llamas-González, Madelaine Sugasti, José González-Santamaría   +4 more
doaj   +1 more source

Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]

, 2013
The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L., Fazakerley, John K., Fragkoudis, Rennos, Human, Stacey, Kohl, Alain, McFarlane, Melanie, Schnettler, Esther, Siu, Ricky W. C., Watson, Mick   +8 more
core   +3 more sources

Neurocognitive impacts of arbovirus infections [PDF]

Journal of Neuroinflammation, 2020
AbstractArthropod-borne viruses or arbovirus, are most commonly associated with acute infections, resulting on various symptoms ranging from mild fever to more severe disorders such as hemorrhagic fever. Moreover, some arboviral infections can be associated with important neuroinflammation that can trigger neurological disorders including encephalitis,
Clé, Marion, Eldin, Patrick, Briant, Laurence, Lannuzel, Annie, Simonin, Yannick, van de Perre, Philippe, Cabié, André, Salinas, Sara   +7 more
openaire   +3 more sources

Circulation of Dirofilaria immitis and Dirofilaria repens in the Danube Delta Biosphere Reserve, Romania

Parasites & Vectors, 2018
Background Dirofilariosis is an emerging vector-borne parasitic disease in Europe. Monitoring of wild and domestic carnivores demonstrated circulation of Dirofilaria spp. in Romania in the past.
Alexandru Tomazatos, Daniel Cadar, Edina Török, Iulia Maranda, Cintia Horváth, Lujza Keresztes, Marina Spinu, Stephanie Jansen, Hanna Jöst, Jonas Schmidt-Chanasit, Egbert Tannich, Renke Lühken   +11 more
doaj   +1 more source

New adhesive traps to monitor urban mosquitoes with a case study to assess the efficacy of insecticide control strategies in temperate areas [PDF]

, 2015
Background: Urban mosquitoes in temperate regions may represent a high nuisance and are associated with the risk of arbovirus transmission. Common practices to reduce this burden, at least in Italian highly infested urban areas, imply calendar-based ...
Caputo, Beniamino, DELLA TORRE, Alessandra, Ienco, Annamaria, Manica, Mattia, Petrarca, Vincenzo, Rosà, Roberto   +5 more
core   +2 more sources