Results 11 to 20 of about 18,532 (196)

An mRNA vaccine against rabies provides strong and durable protection in mice

Frontiers in Immunology, 2023
IntroductionRabies is a serious public health problem worldwide for which an effective treatment method is lacking but can be prevented by vaccines.
Miao Li, Miao Li, Enyue Fang, Enyue Fang, Yunpeng Wang, Leitai Shi, Jia Li, Qinhua Peng, Xingxing Li, Danhua Zhao, Xiaohui Liu, Xiaohui Liu, Xinyu Liu, Jingjing Liu, Hongshan Xu, Hongyu Wang, Yanqiu Huang, Ren Yang, Guangzhi Yue, Yue Suo, Xiaohong Wu, Shouchun Cao, Yuhua Li   +22 more
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Construction of a Dengue NanoLuc Reporter Virus for In Vivo Live Imaging in Mice

Viruses, 2022
Since the first isolation in 1943, the dengue virus (DENV) has spread throughout the world, but effective antiviral drugs or vaccines are still not available. To provide a more stable reporter DENV for vaccine development and antiviral drug screening, we
Enyue Fang, Xiaohui Liu, Miao Li, Jingjing Liu, Zelun Zhang, Xinyu Liu, Xingxing Li, Wenjuan Li, Qinhua Peng, Yongxin Yu, Yuhua Li   +10 more
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Using Background Sequencing Data to Anticipate DENV-1 Circulation in the Lao PDR

Microorganisms, 2021
Since its first detection in 1979, dengue fever has been considered a major public health issue in the Lao People’s Democratic Republic (PDR). Dengue virus (DENV) serotype 1 was the cause of an epidemic in 2010–2011.
Elodie Calvez, Phaithong Bounmany, Charlotte Balière, Somphavanh Somlor, Souksakhone Viengphouthong, Thonglakhone Xaybounsou, Sitsana Keosenhom, Kitphithak Fangkham, Paul T. Brey, Valérie Caro, Vincent Lacoste, Marc Grandadam   +11 more
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Zika virus and temperature modulate Elizabethkingia anophelis in Aedes albopictus

Parasites & Vectors, 2021
Background Vector-borne pathogens must survive and replicate in the hostile environment of an insect’s midgut before successful dissemination. Midgut microbiota interfere with pathogen infection by activating the basal immunity of the mosquito and by ...
Maria G. Onyango, Rachel Lange, Sean Bialosuknia, Anne Payne, Nicholas Mathias, Lili Kuo, Aurelien Vigneron, Dilip Nag, Laura D. Kramer, Alexander T. Ciota   +9 more
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Resistance status of Anopheles gambiae (s.l.) to four commonly used insecticides for malaria vector control in South-East Nigeria

Parasites & Vectors, 2020
Background Progress made in the control of malaria vectors globally is largely due to the use of insecticides. However, success in the fight against malaria has slowed down or even stalled due to a host of factors including insecticide resistance.
Okechukwu Chukwuekezie, Emmanuel Nwosu, Udoka Nwangwu, Festus Dogunro, Cosmas Onwude, Nneka Agashi, Ebuka Ezihe, Clementina Anioke, Stephen Anokwu, Emelda Eloy, Peter Attah, Francis Orizu, Sylvester Ewo, Angela Okoronkwo, Anumba Joseph, Ijeoma Ikeakor, Sylvester Haruna, Virgile Gnanguenon   +17 more
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Adaptive evolution of West Nile virus facilitated increased transmissibility and prevalence in New York State

Emerging Microbes and Infections, 2022
West Nile virus (WNV; Flavivirus, Flaviviridae) was introduced to New York State (NYS) in 1999 and rapidly expanded its range through the continental United States (US). Apart from the displacement of the introductory NY99 genotype with the WN02 genotype,
Sean M. Bialosuknia, Alan P. Dupuis II, Steven D. Zink, Cheri A. Koetzner, Joseph G. Maffei, Jennifer C. Owen, Hannah Landwerlen, Laura D. Kramer, Alexander T. Ciota   +8 more
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Ecological niche modeling for predicting the potential geographical distribution of Aedes species (Diptera: Culicidae): A case study of Enugu State, Nigeria

Parasite Epidemiology and Control, 2021
Arbovirus transmission by Aedes mosquitoes has long been a significant problem in Africa. In West Africa, Aedes vector management faces significant challenges; lack of recent Aedes distributional data and potential distributional modeling hinder ...
K. Omar, H.S. Thabet, R.A. TagEldin, C.C. Asadu, O.C. Chukwuekezie, J.C. Ochu, F.A. Dogunro, U.C. Nwangwu, O.C. Onwude, E.K. Ezihe, C.C. Anioke, H. Arimoto   +11 more
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Metagenomic sequencing characterizes a wide diversity of viruses in field mosquito samples in Nigeria

Scientific Reports, 2022
Mosquito vectors are a tremendous public health threat. One in six diseases worldwide is vector-borne transmitted mainly by mosquitoes. In the last couple of years, there have been active Yellow fever virus (YFV) outbreaks in many settings in Nigeria ...
Judith U. Oguzie, Udoka C. Nwangwu, Paul E. Oluniyi, Testimony J. Olumade, Uwem E. George, Akano Kazeem, Bolajoko E. Bankole, Farida O. Brimmo, Chukwuemeka C. Asadu, Okechukwu C. Chukwuekezie, Josephine C. Ochu, Catherine O. Makwe, Festus A. Dogunro, Cosmas O. Onwude, William E. Nwachukwu, Ebuka K. Ezihe, Gilkenny K. Okonkwo, Ndubuisi E. Umazi, Jacob Maikere, Nneka O. Agashi, Emelda I. Eloy, Stephen O. Anokwu, Angela I. Okoronkwo, Ebuka M. Nwosu, Sandra O. Etiki, Ifeoma M. Ngwu, Chikwe Ihekweazu, Onikepe A. Folarin, Isaac O. O. Komolafe, Christian T. Happi   +29 more
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Hepatitis E virus outbreak associated with rainfall in the Central African Republic in 2008-2009

BMC Infectious Diseases, 2020
Background Infection by hepatitis E virus (HEV) can cause a high burden of morbidity and mortality in countries with poor access to clean water and sanitation. Our study aimed to investigate the situation of HEV infections in the Central African Republic
Vianney Tricou, Julie Bouscaillou, Gina-Laure Laghoe-Nguembe, Aubin Béré, Xavier Konamna, Benjamin Sélékon, Emmanuel Nakouné, Mirdad Kazanji, Narcisse P. Komas   +8 more
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Arbovirus Epidemiology: The Mystery of Unnoticed Epidemics in Ghana, West Africa

Microorganisms, 2022
It is evident that all the countries surrounding Ghana have experienced epidemics of key arboviruses of medical importance, such as the recent dengue fever epidemic in Burkina Faso. Therefore, Ghana is considered a ripe zone for epidemics of arboviruses,
Eric Agboli, Alexandru Tomazatos, Oumou Maiga-Ascofaré, Jürgen May, Renke Lühken, Jonas Schmidt-Chanasit, Hanna Jöst   +6 more
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