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Entre o desconhecido e o emergente: mapeando os vírus Oropouche e Mayaro no Brasil [PDF]

Cadernos de Saúde Pública
As arboviroses são doenças infecciosas causadas por vírus transmitidos por artrópodes. Antes da introdução dos vírus Chikungunya e Zika no Brasil, o vírus Oropouche (OROV) era o segundo arbovírus mais prevalente em humanos, atrás apenas do vírus Dengue ...
Gabriele Nascimento de Oliveira, Léo Shigueki Sato, Antonio Henrique Rosas Novaes, Natan Nascimento de Oliveira, Luciana Dias Ghiraldi Lopes, Dennis Armando Bertolini   +5 more
doaj   +3 more sources

A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection. [PDF]

PLoS Neglected Tropical Diseases
The Mayaro virus (MAYV) is an arthropod-borne virus that causes Mayaro fever, a neglected tropical disease that produces disabling arthralgia. Given the significant threat the dissemination of MAYV poses to global public health, the development of animal
Rafael Borges Rosa, Emilene Ferreira de Castro, Débora de Oliveira Santos, Willyenne Marília Dantas, Camila Ayumi Tanaka, Renata Pessôa Germano Mendes, Ronaldo Celerino da Silva, Cláudio Antônio de Moura Pereira, João Paulo Silva Servato, Anaíra Ribeiro Guedes Fonseca Costa, Roberta Vieira de Morais Bronzoni, Lindomar José Pena   +11 more
doaj   +2 more sources

Implementation of in silico methods to predict common epitopes for vaccine development against Chikungunya and Mayaro viruses

Heliyon, 2021
Being a Positive sense RNA virus the recent reemergence of Chikungunya and Mayaro virus has taken the concern of the leading scientific communities of the world.
Hammadul Hoque, Rahatul Islam, Mashiur Rahaman   +2 more
exaly   +3 more sources

Will Mayaro virus be responsible for the next outbreak of an arthropod-borne virus in Brazil?

Brazilian Journal of Infectious Diseases, 2017
Mayaro virus is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade ...
Danillo Lucas Alves Esposito, Benedito Antônio Lopes Da Fonseca   +1 more
exaly   +3 more sources

Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors

Microorganisms, 2021
Despite the emerging threat of the Mayaro virus (MAYV) in Central and South-America, there are no licensed antivirals or vaccines available for this neglected mosquito-borne virus.
Lana Langendries, Rana Abdelnabi, Johan Neyts   +2 more
exaly   +3 more sources

Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021 [PDF]

Emerging Infectious Diseases
We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018–2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D.
Julia Forato, Cássio A. Meira, Ingra M. Claro, Mariene R. Amorim, Gabriela F. de Souza, Stefanie P. Muraro, Daniel A. Toledo-Teixeira, Miguel F. Dias, Cátia A. R. Meneses, Rodrigo N. Angerami, Pritesh Lalwani, Scott C. Weaver, Ester C. Sabino, Nuno R. Faria, William M. de Souza, Fabiana Granja, José Luiz Proenca-Modena   +16 more
doaj   +2 more sources

Mayaro Virus: An Emerging Alphavirus in the Americas [PDF]

Viruses
Mayaro virus (MAYV) is an arbovirus first isolated in Trinidad and Tobago in 1954. MAYV is the causative agent of Mayaro fever, which is characterised by high fever, maculopapular rash, myalgia and arthralgia.
Lily Li Lin Wei, Rufaro Tom, Young Chan Kim   +2 more
doaj   +2 more sources

Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability [PDF]

Viruses
The Mayaro virus (MAYV) is an arbovirus with emerging potential, though with a limited understanding of its epidemiology and evolution due to the lack of studies and surveillance. Here, we investigated 71 MAYV genome sequences from the Americas available
Mikaela dos Santos Marinho, Giulia Magalhães Ferreira, Victória Riquena Grosche, Nilson Nicolau-Junior, Túlio de Lima Campos, Igor Andrade Santos, Ana Carolina Gomes Jardim   +6 more
doaj   +2 more sources

Mayaro Virus Infects Human Brain Cells and Induces a Potent Antiviral Response in Human Astrocytes

Viruses, 2021
Mayaro virus (MAYV) and chikungunya virus (CHIKV) are known for their arthrotropism, but accumulating evidence shows that CHIKV infections are occasionally associated with serious neurological complications. However, little is known about the capacity of
Michèle Bengue, Pauline Ferraris, Jonathan Barthelemy, Cheikh Tidiane Diagne, Rodolphe Hamel, Florian Liégeois, Antoine Nougairède, Xavier de Lamballerie, Yannick Simonin, Julien Pompon, Sara Salinas, Dorothée Missé   +11 more
doaj   +1 more source

Favipiravir Inhibits Mayaro Virus Infection in Mice

Viruses, 2021
Mayaro virus (MAYV) is an emergent alphavirus that causes MAYV fever. It is often associated with debilitating symptoms, particularly arthralgia and myalgia.
Michèle Bengue, Ai-rada Pintong, Florian Liegeois, Antoine Nougairède, Rodolphe Hamel, Julien Pompon, Xavier de Lamballerie, Pierre Roques, Valérie Choumet, Dorothée Missé   +9 more
doaj   +1 more source