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Mouse Models of Mayaro Virus [PDF]

open access: yesViruses, 2023
Mayaro virus (MAYV), the etiologic agent of Mayaro fever, leads patients to severe myalgia and arthralgia, which can have a major impact on public health in all the countries where the virus circulates. The emergence and dissemination of new viruses have
Rafael Borges Rosa   +4 more
doaj   +2 more sources

Will Mayaro virus be responsible for the next outbreak of an arthropod-borne virus in Brazil?

open access: yesBrazilian Journal of Infectious Diseases, 2017
Mayaro virus is an alphavirus from the Togaviridae family and is transmitted mainly by Hemagogus mosquitoes. This virus circulates in high-density tropical forests or rural areas of Central and South America causing a disease characterized by high-grade ...
Danillo Lucas Alves Esposito   +1 more
doaj   +3 more sources

A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases
The Mayaro virus (MAYV) is an arthropod-borne virus that causes Mayaro fever, a neglected tropical disease that produces disabling arthralgia. Given the significant threat the dissemination of MAYV poses to global public health, the development of animal
Rafael Borges Rosa   +11 more
doaj   +2 more sources

Repurposing Drugs for Mayaro Virus: Identification of EIDD-1931, Favipiravir and Suramin as Mayaro Virus Inhibitors

open access: yesMicroorganisms, 2021
Despite the emerging threat of the Mayaro virus (MAYV) in Central and South-America, there are no licensed antivirals or vaccines available for this neglected mosquito-borne virus.
Lana Langendries   +3 more
doaj   +3 more sources

Immunogenic recombinant Mayaro virus-like particles present natively assembled glycoprotein [PDF]

open access: yesnpj Vaccines
Virus-like particles (VLPs) are an established vaccine platform and can be strong immunogens capable of eliciting both humoral and cellular immune responses against a range of pathogens. Here, we show by cryo-electron microscopy that VLPs of Mayaro virus,
Young Chan Kim   +13 more
doaj   +2 more sources

Evolutionary Profile of Mayaro Virus in the Americas: An Update into Genome Variability [PDF]

open access: yesViruses
The Mayaro virus (MAYV) is an arbovirus with emerging potential, though with a limited understanding of its epidemiology and evolution due to the lack of studies and surveillance. Here, we investigated 71 MAYV genome sequences from the Americas available
Mikaela dos Santos Marinho   +6 more
doaj   +2 more sources

Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018–2021 [PDF]

open access: yesEmerging Infectious Diseases
We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018–2021 from Roraima State, Brazil. We also isolated MAYV strains and confirmed that these cases were caused by genotype D.
Julia Forato   +16 more
doaj   +2 more sources

Fact Sheet: Mayaro Virus

open access: yesEDIS, 2021
Mayaro virus (MAYV) can be spread from mosquitoes to humans. The geographic distribution of Mayaro virus is expanding from South and Central America into the Caribbean Islands, which means that, under the right conditions, this virus could one day ...
Lawrence E Reeves, Lindsay Campbell
doaj   +3 more sources

Alterations in the Cellular Metabolic Footprint Induced by Mayaro Virus

open access: yesBioMed, 2023
Mayaro virus is a neglected virus that causes a mild, dengue-like febrile syndrome characterized by fever, headache, rash, retro-orbital pain, vomiting, diarrhea, articular edemas, myalgia, and severe arthralgia, symptoms which may persist for months and
Ceyla M. O. Castro   +7 more
doaj   +1 more source

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