Results 1 to 10 of about 3,801,410 (311)

Virus evolution: the mutualism-antagonism continuum of virus-virus interactions

open access: yesVirologie
The conference gathered experts from many fields working on various aspects of virus-virus interactions, ranging from mutualistic to parasitic, and harnessing different approaches to studying virus evolution (e.g., molecular biology, theory, mathematical modelling, genomics, phylogenetics, clinical studies, laboratory experiments).
Turner, Paul, Michalakis, Yannis
openaire   +4 more sources

SARS-CoV-2 variants: Impact on biological and clinical outcome

open access: yesFrontiers in Medicine, 2022
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that was first identified in December 2019, in Wuhan, China was found to be the etiological agent for a novel respiratory infection that led to a Coronavirus Induced Disease named COVID-19.
Shakuntala Mahilkar   +13 more
doaj   +1 more source

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism

open access: yesmBio, 2019
APOBEC3B is a single-stranded DNA cytosine deaminase with beneficial innate antiviral functions. However, misregulated APOBEC3B can also be detrimental by inflicting APOBEC signature C-to-T and C-to-G mutations in genomic DNA of multiple cancer types ...
Gabriel J. Starrett   +13 more
doaj   +1 more source

Virus Evolution and Genetics

open access: yes, 2017
Viruses are very diverse and they infect organisms from all domains of life and across all ecosystems, but related viruses often infect very different types of organisms, pointing to their very ancient origins. Three commonly proposed mechanisms for the origins of viruses are: Viruses descended from primitive precellular life forms; viruses are escaped
openaire   +1 more source

Expanding networks of RNA virus evolution [PDF]

open access: yesBMC Biology, 2012
In a recent BMC Evolutionary Biology article, Huiquan Liu and colleagues report two new genomes of double-stranded RNA (dsRNA) viruses from fungi and use these as a springboard to perform an extensive phylogenomic analysis of dsRNA viruses. The results support the old scenario of polyphyletic origin of dsRNA viruses from different groups of positive ...
Koonin Eugene V, Dolja Valerian V
openaire   +3 more sources

SARS-CoV-2 Variants from Long-Term, Persistently Infected Immunocompromised Patients Have Altered Syncytia Formation, Temperature-Dependent Replication, and Serum Neutralizing Antibody Escape

open access: yesViruses
SARS-CoV-2 infection of immunocompromised individuals often leads to prolonged detection of viral RNA and infectious virus in nasal specimens, presumably due to the lack of induction of an appropriate adaptive immune response.
Camille Wouters   +10 more
doaj   +1 more source

Subterranean Clover Stunt Virus Revisited: Detection of Two Missing Genome Components

open access: yesViruses, 2019
Subterranean clover stunt virus (SCSV) is a type species of the genus Nanovirus in the family Nanoviridae. It was the first single-stranded DNA plant virus with a multipartite genome, of which genomic DNA sequences had been determined.
Dennis Knierim   +9 more
doaj   +1 more source

Emergence and adaptive evolution of Nipah virus [PDF]

open access: yesTransboundary and Emerging Diseases, 2019
Since its first emergence in 1998 in Malaysia, Nipah virus (NiV) has become a great threat to domestic animals and humans. Sporadic outbreaks associated with human-to-human transmission caused hundreds of human fatalities. Here, we collected all available NiV sequences and combined phylogenetics, molecular selection, structural biology and receptor ...
Kemang Li   +11 more
openaire   +2 more sources

Genetic Diversity of Infectious Bronchitis Virus Genotype II in Poland

open access: yesPathogens
The epidemiological situation in Poland for IBV GII (formerly known as D1466) has seemed stable over the years, but an increase in such infections has been recently reported. In this study, genetic characterization of the representatives of this genotype
Anna Pikuła   +3 more
doaj   +1 more source

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

open access: yesViruses, 2017
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes.
Cody J. Warren   +3 more
doaj   +1 more source

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