Results 11 to 20 of about 258,340 (266)

Structural constraints on RNA virus evolution [PDF]

Journal of Virology, 1999
The recently discovered hepatitis G virus (HGV) or GB virus C (GBV-C) is widely distributed in human populations, and homologues such as HGV/GBV-CCPZ and GBV-A are found in a variety of different primate species.
Smith, D B, Simmonds, P
core   +4 more sources

The logic of virus evolution

Cell Host & Microbe, 2022
Viruses are obligate intracellular parasites. Despite their dependence on host cells, viruses are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked in arms races with the hosts. Here, we discuss a simple functional logic to explain virus macroevolution that appears to define the course of virus evolution.
Koonin, Eugene, Dolja, Valerian, Krupovic, Mart   +2 more
openaire   +3 more sources

Evolution of neurovirulent Zika virus [PDF]

Science, 2017
A Zika virus mutation leads to increased ...
Screaton, G, Mongkolsapaya, J
openaire   +2 more sources

JC virus evolution and its association with human populations [PDF]

, 2006
The ubiquitous human polyomavirus JC (JCV) is a small double-stranded DNA virus that establishes a persistent infection, and it is often transmitted from parents to children.
Edward C. Holmes, Andrew Rambaut, Shackelton, Laura A., Rambaut, Andrew, Oliver G. Pybus, Laura A. Shackelton, Pybus, Oliver G., Holmes, Edward C.   +7 more
core   +1 more source

Evolution of human respiratory virus epidemics [PDF]

F1000Research, 2020
Background: Pathogens are often assumed to evolve towards reduced virulence, but counterexamples abound. Faced with a new pathogen, such as SARS-CoV-2, it is crucial to be able to forecast the case fatality rate (CFR) and the overall disease burden.
Nash D. Rochman, Yuri I. Wolf, Eugene V. Koonin   +2 more
openaire   +5 more sources

Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs [PDF]

, 2012
The latest human influenza pandemic highlights the ability of influenza viruses to jump species barriers and emerge in new hosts, as well as the role of pigs in generating viruses with pandemic potential.
Pablo R Murcia, Mario Caccamo, Baillie Gregory J., Gregory J. Baillie (110994), Doug Ormond (161033), Jennifer A. Mumford (161049), Grenfell Bryan T., Lloyd Lucy, Lloyd, Lucy, Battista Patrizia, Patrizia Battista, Jennifer A Mumford, Wood, James L.N., Patrizia Battista (161011), Ramirez-Gonzalez Ricardo H., Elton, Debra, Ormond Doug, Joseph Hughes (42279), Oliver Karen, Edward C. Holmes (35215), Battista, Patrizia, Holmes Edward C., Caccamo, Mario, Edward C Holmes, Wood, James L. N., Wood, James LN, Oliver, Karen, Caccamo Mario, Ricardo H Ramirez-Gonzalez, Wood James L. N., Hughes Joseph, Ricardo H. Ramirez-Gonzalez (161026), Ramirez-Gonzalez, Ricardo H., Joseph Hughes, Lucy Lloyd (161017), Murcia, Pablo R, Bryan T Grenfell, Debra Elton (29877), Ormond, Doug, Paul Kellam, Mario Caccamo (42188), Mumford Jennifer A., Murcia, Pablo R., Baillie, Gregory J., Karen Oliver, Debra Elton, Doug Ormond, Grenfell, Bryan T., Kellam Paul, Gregory J Baillie, Paul Kellam (6413), Pablo R. Murcia (111005), Murcia Pablo R., Elton Debra, Holmes, Edward C, James L. N. Wood (111001), Holmes, Edward C., Lucy Lloyd, Mumford, Jennifer A, Hughes, Joseph, Baillie, Gregory J, Mumford, Jennifer A., Karen Oliver (161040), Kellam, Paul, Grenfell, Bryan T, Ramirez-Gonzalez, Ricardo H, Bryan T. Grenfell (44234), James L N Wood   +67 more
core   +1 more source

THE EVOLUTION OF VIRULENCE IN A PLANT VIRUS [PDF]

Evolution, 2003
The evolution of virulence is a rapidly growing field of research, but few reports deal with the evolution of virulence in natural populations of parasites. We present here an observational and experimental analysis of the evolution of virulence of the plant virus Cucumber mosaic virus (CMV) during an epidemic on tomato in eastern Spain. Three types of
Fernando, Escriu, Aurora, Fraile, Fernando, García-Arenal   +2 more
openaire   +2 more sources

Exceptional Convergent Evolution in a Virus [PDF]

Genetics, 1997
Abstract Replicate lineages of the bacteriophage ϕX 174 adapted to growth at high temperature on either of two hosts exhibited high rates of identical, independent substitutions. Typically, a dozen or more substitutions accumulated in the 5.4-kilobase genome during propagation. Across the entire data set of nine lineages, 119 independent
J J, Bull, M R, Badgett, H A, Wichman, J P, Huelsenbeck, D M, Hillis, A, Gulati, C, Ho, I J, Molineux   +7 more
openaire   +2 more sources

Evolution and Vaccination of Influenza Virus [PDF]

Journal of Computational Biology, 2017
In this study, we present an application paradigm in which an unsupervised machine learning approach is applied to the high-dimensional influenza genetic sequences to investigate whether vaccine is a driving force to the evolution of influenza virus. We first used a visualization approach to visualize the evolutionary paths of vaccine-controlled and ...
Ham Ching Lam, Xuan Bi, Srinand Sreevatsan, Daniel Boley   +3 more
openaire   +2 more sources

Dinucleotide evolutionary dynamics in influenza A virus [PDF]

, 2019
Significant biases of dinucleotide composition in many RNA viruses including influenza A virus have been reported in recent years. Previous studies have showed that a codon-usage-altered influenza mutant with elevated CpG usage is attenuated in mammalian
Poon, LLM, Fan, RLY, Gu, H, Wang, D
core   +1 more source