In vivo evidence for quasispecies distributions in the bovine respiratory syncytial virus genome [PDF]
We analyzed the genetic evolution of bovine respiratory syncytial virus (BRSV) isolate W2-00131, from its isolation in bovine turbinate (BT) cells to its inoculation in calves.
Mirandette, Carole +5 more
core +1 more source
Is HIV short-sighted? Insights from a multistrain nested model [PDF]
An important component of pathogen evolution at the population level is evolution within hosts. Unless evolution within hosts is very slow compared to the duration of infection, the composition of pathogen genotypes within a host is likely to change ...
Lythgoe, KA +8 more
core +1 more source
The evolution of virus–induced apoptosis
Viruses from several different families are able to exploit their host's cell death programmes so as to maximize viral fitness. Consideration of the evolution of such strategies has lead to the suggestion that the virus should inhibit apoptosis, in order to prolong the life of the cell and thereby maximize the number of progeny virions.
Krakauer, DC, Payne, RJH
openaire +4 more sources
Sequence-based taxonomic framework for the classification of uncultured single-stranded DNA viruses of the family Genomoviridae [PDF]
: With the advent of metagenomics approaches, a large diversity of known and unknown viruses has been identified in various types of environmental, plant, and animal samples.
core +1 more source
Evolution and Epidemiology of Chikungunya Virus
Chikungunya is a mosquito-borne Alphavirus that is spreading worldwide in the tropical areas and that has a 11.8 kb RNA genome. The most relevant vectors belong to the genus Aedes and contribute to the diffusion of the three different genotypes of the virus from the original site of first identification in East Africa.
Rossini, Giada +2 more
openaire +2 more sources
Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman +53 more
core +1 more source
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
I. M. Jones +21 more
core +1 more source
Arthropods harbor a largely undocumented diversity of RNA viruses. Some arthropods, like mosquitoes, can transmit viruses to vertebrates but are themselves parasitized by other arthropod species, such as mites.
HOLMES, Edward +14 more
core +1 more source
Pingu virus : a new picornavirus in penguins from Antarctica [PDF]
Picornaviridae family comprises single-stranded, positive-sense RNA viruses distributed into forty-seven genera. Picornaviruses have a broad host range and geographic distribution in all continents.
Sanfilippo, Luiz Francisco +11 more
core +1 more source
Revealing RNA virus diversity and evolution in unicellular algae transcriptomes [PDF]
Remarkably little is known about the diversity and evolution of RNA viruses in unicellular eukaryotes. We screened a total of 570 transcriptomes from the Marine Microbial Eukaryote Transcriptome Sequencing Project that encompasses a wide diversity of ...
HOLMES, Edward +5 more
core +1 more source

