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Flavivirus NS1 and Its Potential in Vaccine Development

open access: yesVaccines, 2021
The Flavivirus genus contains many important human pathogens, including dengue, Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) and Zika (ZIK) viruses.
Alan Barrett
exaly   +3 more sources

Flavivirus: From Structure to Therapeutics Development

open access: yesLife, 2021
Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao, Xin Zhou, Jing Shen
exaly   +3 more sources

Atlastin-2-mediated endoplasmic reticulum membrane tethering is critical for flavivirus replication. [PDF]

open access: yesPLoS Biology
Flaviviruses (genus Orthoflavivirus) are arthropod-borne viruses which cause approximately 400 million annual global infections in humans. Flavivirus infection requires cellular machinery to facilitate replication and spread.
Jonathan Einterz Owen   +12 more
doaj   +2 more sources

Flavivirus-Mosquito Interactions

open access: yesViruses, 2014
The Flavivirus genus is in the family Flaviviridae and is comprised of more than 70 viruses. These viruses have a broad geographic range, circulating on every continent except Antarctica.
Dana Vanlandingham   +2 more
exaly   +3 more sources

Phenotypic and Genetic Variability of Isolates of ZIKV-2016 in Brazil

open access: yesMicroorganisms, 2022
The possibility of a Zika virus epidemic resurgence requires studies to understand its mechanisms of pathogenicity. Here, we describe the isolation of the Zika virus from breast milk (Rio-BM1) and compare its genetic and virological properties with two ...
Lidiane Menezes Souza Raphael   +11 more
doaj   +1 more source

Chikungunya Virus Shedding in Semen: A Case Series

open access: yesViruses, 2022
Background: Chikungunya is a viral disease that is transmitted by mosquitoes. It is characterized by an acute onset of fever and severe arthralgia. Methods: We describe six cases of acute and post-acute chikungunya in which viral RNA was detected in ...
Ezequias B. Martins   +16 more
doaj   +1 more source

Implementación de un sistema de detección de flavivirus en mosquitos

open access: yesMemorias del Instituto de Investigaciones en Ciencias de la Salud, 2021
Los Flavivirus constituyen virus transmitidos por artrópodos, principalmente mosquitos. Pueden producir enfermedades en humanos y animales, también incluyen virus específicos de insectos que solo infectan y se replican en los insectos, no así en ...
Fátima Cardozo   +8 more
doaj   +1 more source

Co-Circulation of Two Independent Clades and Persistence of CHIKV-ECSA Genotype during Epidemic Waves in Rio de Janeiro, Southeast Brazil

open access: yesPathogens, 2020
The Chikungunya virus infection in Brazil has raised several concerns due to the rapid dissemination of the virus and its association with several clinical complications.
Allison Araújo Fabri   +13 more
doaj   +1 more source

Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication

open access: yesAdvanced Science, 2023
Flavivirus remodels the host endoplasmic reticulum (ER) to generate replication compartments (RCs) as the fundamental structures to accommodate viral replication.
Yali Ci   +6 more
doaj   +1 more source

Guapiaçu virus, a new insect-specific flavivirus isolated from two species of Aedes mosquitoes from Brazil

open access: yesScientific Reports, 2021
Classical insect-flaviviruses (cISFVs) and dual host-related insect-specific flavivirus (dISFV) are within the major group of insect-specific flavivirus.
Geovani de Oliveira Ribeiro   +23 more
doaj   +1 more source

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