Results 1 to 10 of about 21,500 (114)

Role of quaternary epitopes in eliciting broad neutralization response against multiple flaviviruses [PDF]

open access: yesJournal of Virology
Flaviviruses, or orthoflaviviruses, are arthropod-borne RNA viruses that pose a significant global health threat and co-circulate in many regions across the world.
Ananya Chatterjee, Vidya Mangala Prasad
doaj   +2 more sources

Tetraspanins as Potential Therapeutic Candidates for Targeting Flaviviruses

open access: yesFrontiers in Immunology, 2021
Tetraspanin family of proteins participates in numerous fundamental signaling pathways involved in viral transmission, virus-specific immunity, and virus-mediated vesicular trafficking.
Girish Neelakanta, Hameeda Sultana
exaly   +3 more sources

Marine-Derived Natural Products Against Flaviviruses: Mechanisms, Evidence, and Future Directions [PDF]

open access: yesMarine Drugs
Although flaviviruses, including DENV, ZIKV and JEV, remain important causes of febrile, congenital, and neurological diseases, treatment options remain largely supportive, with limited availability of virus-specific antiviral therapies. Marine organisms
Hyeon Seung Park   +5 more
doaj   +2 more sources

Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses

open access: yesPLoS Pathogens, 2022
Flaviviruses, which are globally distributed and cause a spectrum of potentially severe illnesses, pose a major threat to public health. Although Flaviviridae viruses, including flaviviruses, possess similar genome structures, only the flaviviruses ...
Takasuke Fukuhara   +2 more
exaly   +2 more sources

Magnitude of Antibody Cross-Reactivity in Medically Important Mosquito-Borne Flaviviruses: A Systematic Review

open access: yesInfection and Drug Resistance, 2021
Adugna Endale,1,2 Girmay Medhin,1 Koyamo Darfiro,3 Nigatu Kebede,1 Mengistu Legesse1 1Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Dire Dawa ...
Adugna Endale   +2 more
exaly   +2 more sources

Phenotypic and Genetic Studies of the Viral Lineage Associated with the Recent Yellow Fever Outbreak in Brazil

open access: yesViruses, 2022
Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine ...
Nathália Dias Furtado   +4 more
doaj   +1 more source

Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections

open access: yesTropical Medicine and Infectious Disease, 2021
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-visual
Youssef A. Kousa, Reafa A. Hossain
doaj   +1 more source

An Advax-Adjuvanted Inactivated Cell-Culture Derived Japanese Encephalitis Vaccine Induces Broadly Neutralising Anti-Flavivirus Antibodies, Robust Cellular Immunity and Provides Single Dose Protection

open access: yesVaccines, 2021
ccJE+Advax is an inactivated cell culture Japanese encephalitis (JE) vaccine formulated with Advax, a novel polysaccharide adjuvant based on delta inulin. This vaccine has previously shown promise in murine and equine studies and the current study sought
Tomoyoshi Komiya   +3 more
doaj   +1 more source

Widespread Circulation of Flaviviruses in Horses and Birds in Northeastern Spain (Catalonia) between 2010 and 2019

open access: yesViruses, 2021
The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses ...
Sebastian Napp   +14 more
doaj   +1 more source

Flavivirus–Host Interaction Landscape Visualized through Genome-Wide CRISPR Screens

open access: yesViruses, 2022
Flaviviruses comprise several important human pathogens which cause significant morbidity and mortality worldwide. Like any other virus, they are obligate intracellular parasites.
Aditi Kanojia   +3 more
doaj   +1 more source

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