Results 1 to 10 of about 26,784 (178)

Role of quaternary epitopes in eliciting broad neutralization response against multiple flaviviruses [PDF]

open access: yesJournal of Virology
Flaviviruses, or orthoflaviviruses, are arthropod-borne RNA viruses that pose a significant global health threat and co-circulate in many regions across the world.
Ananya Chatterjee, Vidya Mangala Prasad
doaj   +2 more sources

Flaviviruses as agents of childhood central nervous system infections in Brazil [PDF]

open access: yesNew Microbes and New Infections, 2019
Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj   +4 more sources

Marine-Derived Natural Products Against Flaviviruses: Mechanisms, Evidence, and Future Directions [PDF]

open access: yesMarine Drugs
Although flaviviruses, including DENV, ZIKV and JEV, remain important causes of febrile, congenital, and neurological diseases, treatment options remain largely supportive, with limited availability of virus-specific antiviral therapies. Marine organisms
Hyeon Seung Park   +5 more
doaj   +2 more sources

Phenotypic and Genetic Studies of the Viral Lineage Associated with the Recent Yellow Fever Outbreak in Brazil

open access: yesViruses, 2022
Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine ...
Nathália Dias Furtado   +4 more
doaj   +1 more source

Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections

open access: yesTropical Medicine and Infectious Disease, 2021
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-visual
Youssef A. Kousa, Reafa A. Hossain
doaj   +1 more source

An Advax-Adjuvanted Inactivated Cell-Culture Derived Japanese Encephalitis Vaccine Induces Broadly Neutralising Anti-Flavivirus Antibodies, Robust Cellular Immunity and Provides Single Dose Protection

open access: yesVaccines, 2021
ccJE+Advax is an inactivated cell culture Japanese encephalitis (JE) vaccine formulated with Advax, a novel polysaccharide adjuvant based on delta inulin. This vaccine has previously shown promise in murine and equine studies and the current study sought
Tomoyoshi Komiya   +3 more
doaj   +1 more source

Widespread Circulation of Flaviviruses in Horses and Birds in Northeastern Spain (Catalonia) between 2010 and 2019

open access: yesViruses, 2021
The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses ...
Sebastian Napp   +14 more
doaj   +1 more source

Flavivirus–Host Interaction Landscape Visualized through Genome-Wide CRISPR Screens

open access: yesViruses, 2022
Flaviviruses comprise several important human pathogens which cause significant morbidity and mortality worldwide. Like any other virus, they are obligate intracellular parasites.
Aditi Kanojia   +3 more
doaj   +1 more source

From Capsids to Complexes: Expanding the Role of TRIM5α in the Restriction of Divergent RNA Viruses and Elements

open access: yesViruses, 2021
An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population ...
Kevin M. Rose   +6 more
doaj   +1 more source

Quercetin Inhibits Hsp70 Blocking of Bovine Viral Diarrhea Virus Infection and Replication in the Early Stage of Virus Infection

open access: yesViruses, 2022
Bovine viral diarrhea virus (BVDV), a positive-strand RNA virus of the genus Pestivirus in the Flaviviridae family, is the causative agent of viral diarrheal disease in bovine.
Nannan Chen   +10 more
doaj   +1 more source

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