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Biochemistry and Molecular Biology of Flaviviruses [PDF]

open access: yesChemical Reviews, 2018
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile, yellow fever, and Zika viruses, are critically important human pathogens that sicken a staggeringly high number of humans every year. Most of these pathogens are transmitted by mosquitos, and not surprisingly, as the earth warms and human populations grow and move,
Ruben Soto-Acosta   +2 more
exaly   +6 more sources

Biosensors for the detection of flaviviruses: A review [PDF]

open access: yesSynthetic and Systems Biotechnology
Flaviviruses affect the lives of millions of people in endemic regions and also have the potential to impact non-endemic areas. Factors such as climate change, global warming, deforestation, and increased travel and trade are linked to the spread of ...
Blazquez A B, Nereida Jiménez De Oya
exaly   +4 more sources

Magnitude of Antibody Cross-Reactivity in Medically Important Mosquito-Borne Flaviviruses: A Systematic Review

open access: yesInfection and Drug Resistance, 2021
Adugna Endale,1,2 Girmay Medhin,1 Koyamo Darfiro,3 Nigatu Kebede,1 Mengistu Legesse1 1Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Dire Dawa ...
Adugna Endale, Nigatu Kebede
exaly   +2 more sources

Phenotypic and Genetic Studies of the Viral Lineage Associated with the Recent Yellow Fever Outbreak in Brazil

open access: yesViruses, 2022
Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine ...
Nathália Dias Furtado   +4 more
doaj   +1 more source

Causes of Phenotypic Variability and Disabilities after Prenatal Viral Infections

open access: yesTropical Medicine and Infectious Disease, 2021
Prenatal viral infection can lead to a spectrum of neurodevelopmental disabilities or fetal demise. These can include microencephaly, global developmental delay, intellectual disability, refractory epilepsy, deafness, retinal defects, and cortical-visual
Youssef A. Kousa, Reafa A. Hossain
doaj   +1 more source

An Advax-Adjuvanted Inactivated Cell-Culture Derived Japanese Encephalitis Vaccine Induces Broadly Neutralising Anti-Flavivirus Antibodies, Robust Cellular Immunity and Provides Single Dose Protection

open access: yesVaccines, 2021
ccJE+Advax is an inactivated cell culture Japanese encephalitis (JE) vaccine formulated with Advax, a novel polysaccharide adjuvant based on delta inulin. This vaccine has previously shown promise in murine and equine studies and the current study sought
Tomoyoshi Komiya   +3 more
doaj   +1 more source

Widespread Circulation of Flaviviruses in Horses and Birds in Northeastern Spain (Catalonia) between 2010 and 2019

open access: yesViruses, 2021
The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses ...
Sebastian Napp   +14 more
doaj   +1 more source

Flavivirus–Host Interaction Landscape Visualized through Genome-Wide CRISPR Screens

open access: yesViruses, 2022
Flaviviruses comprise several important human pathogens which cause significant morbidity and mortality worldwide. Like any other virus, they are obligate intracellular parasites.
Aditi Kanojia   +3 more
doaj   +1 more source

From Capsids to Complexes: Expanding the Role of TRIM5α in the Restriction of Divergent RNA Viruses and Elements

open access: yesViruses, 2021
An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population ...
Kevin M. Rose   +6 more
doaj   +1 more source

Quercetin Inhibits Hsp70 Blocking of Bovine Viral Diarrhea Virus Infection and Replication in the Early Stage of Virus Infection

open access: yesViruses, 2022
Bovine viral diarrhea virus (BVDV), a positive-strand RNA virus of the genus Pestivirus in the Flaviviridae family, is the causative agent of viral diarrheal disease in bovine.
Nannan Chen   +10 more
doaj   +1 more source

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