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Ocular Manifestations of Flavivirus Infections [PDF]

open access: yesPathogens, 2023
Flaviviruses are a group of positive-sense, single-stranded RNA viruses predominantly transmitted by arthropods (mainly mosquitoes) that cause severe endemic infections and epidemics on a global scale.
Sourour Meziou Zina   +4 more
doaj   +6 more sources

Structures and Functions of the Envelope Glycoprotein in Flavivirus Infections [PDF]

open access: yesViruses, 2017
Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal species. The envelope protein, a structural protein of flavivirus, plays an important role in host cell viral infections.
Xingcui Zhang   +5 more
doaj   +9 more sources

TRIMming down Flavivirus Infections [PDF]

open access: yesViruses
Flaviviruses comprise a large number of arthropod-borne viruses, some of which are associated with life-threatening diseases. Flavivirus infections are rising worldwide, mainly due to the proliferation and geographical expansion of their vectors.
Marion Cannac, Sébastien Nisole
doaj   +6 more sources

Pathogenesis and virulence of flavivirus infections [PDF]

open access: yesVirulence, 2021
The Flavivirus genus consists of >70 members including several that are considered significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be roughly categorised into two phenotypes – systemic disease involving haemorrhage
Sophie Wilhelmina van Leur   +3 more
doaj   +6 more sources

The global incidence and trends of three common flavivirus infections (Dengue, yellow fever, and Zika) from 2011 to 2021 [PDF]

open access: yesFrontiers in Microbiology
BackgroundFlavivirus pose a continued threat to global health, yet their worldwide burden and trends remain poorly quantified. We aimed to evaluate the global, regional, and national incidence of three common flavivirus infections (Dengue, yellow fever ...
Yuanhao Liang, Xingzhu Dai
doaj   +7 more sources

Serological Diagnosis of Flavivirus-Associated Human Infections [PDF]

open access: yesDiagnostics, 2020
Arthropod-borne viruses (arboviruses) belonging to the Flavivirus genus of the Flaviviridae family, are a major public health threat in tropical and subtropical regions, and have recently become a medical concern in temperate zones. Most flaviviruses are
Didier Musso, Philippe Desprès
doaj   +8 more sources

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections [PDF]

open access: yesCell Reports, 2018
Summary: Although the outcome of flavivirus infection can vary from asymptomatic to lethal, environmental factors modulating disease severity are poorly defined.
Larissa B. Thackray   +15 more
doaj   +7 more sources

Role of the complement system in antibody-dependent enhancement of flavivirus infections [PDF]

open access: yesInternational Journal of Infectious Diseases, 2021
Flavivirus infections have increased dramatically in the last decades in tropical and subtropical regions of the world. Antibody-dependent enhancement of dengue virus infections has been one of the main hypotheses to explain severity of disease and one ...
Alana B. Byrne, Laura B. Talarico
doaj   +5 more sources

Cellular Targets for the Treatment of Flavivirus Infections [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Classical antiviral therapy targets viral functions, mostly viral enzymes or receptors. Successful examples include precursor herpesvirus drugs, antiretroviral drugs that target reverse transcriptase and protease, influenza virus directed compounds as ...
Mohammad Khalid Zakaria   +2 more
doaj   +6 more sources

The role of γδ T cells in flavivirus infections: Insights into immune defense and therapeutic opportunities. [PDF]

open access: yesPLoS Neglected Tropical Diseases
γδ T cells are a unique subset of unconventional T cells and an important component of the innate immune system. Unlike conventional αβ T cells, γδ T cells can respond rapidly during the early stages of infection, and their antigen recognition is not ...
Qi Li   +7 more
doaj   +2 more sources

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