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Pathogenesis and virulence of flavivirus infections
Virulence, 2021 The Flavivirus genus consists of >70 members including several that are considered significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be roughly categorised into two phenotypes – systemic disease involving haemorrhage
Sophie Wilhelmina van Leur +3 more
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Role of the complement system in antibody-dependent enhancement of flavivirus infections
International Journal of Infectious Diseases, 2021 Flavivirus infections have increased dramatically in the last decades in tropical and subtropical regions of the world. Antibody-dependent enhancement of dengue virus infections has been one of the main hypotheses to explain severity of disease and one ...
Alana B. Byrne, Laura B. Talarico
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Serological Diagnosis of Flavivirus-Associated Human Infections
Diagnostics, 2020 Arthropod-borne viruses (arboviruses) belonging to the Flavivirus genus of the Flaviviridae family, are a major public health threat in tropical and subtropical regions, and have recently become a medical concern in temperate zones. Most flaviviruses are
Didier Musso, Philippe Desprès
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Frontiers in MicrobiologyBackgroundFlavivirus pose a continued threat to global health, yet their worldwide burden and trends remain poorly quantified. We aimed to evaluate the global, regional, and national incidence of three common flavivirus infections (Dengue, yellow fever ...
Yuanhao Liang, Xingzhu Dai
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Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections
Cell Reports, 2018 Summary: Although the outcome of flavivirus infection can vary from asymptomatic to lethal, environmental factors modulating disease severity are poorly defined.
Larissa B. Thackray +15 more
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Structures and Functions of the Envelope Glycoprotein in Flavivirus Infections
Viruses, 2017 Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal species. The envelope protein, a structural protein of flavivirus, plays an important role in host cell viral infections.
Xingcui Zhang +5 more
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Ocular Manifestations of Flavivirus Infections
Pathogens, 2023 Flaviviruses are a group of positive-sense, single-stranded RNA viruses predominantly transmitted by arthropods (mainly mosquitoes) that cause severe endemic infections and epidemics on a global scale.
Sourour Meziou Zina +4 more
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TRIMming down Flavivirus Infections
VirusesFlaviviruses comprise a large number of arthropod-borne viruses, some of which are associated with life-threatening diseases. Flavivirus infections are rising worldwide, mainly due to the proliferation and geographical expansion of their vectors.
Marion Cannac, Sébastien Nisole
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Antiviral Research, 2022 Epidemics caused by flaviviruses occur globally; however, no antiviral drugs treating flaviviruses infections have yet been developed. Nafamostat (NM) is a protease inhibitor approved for pancreatitis and anti-coagulation.
Yunzheng Yan +20 more
semanticscholar +3 more sources
An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections
Cell Reports, 2018 SUMMARY Powassan virus (POWV) is an emerging tick-transmitted flavivirus that circulates in North America and Russia. Up to 5% of deer ticks now test positive for POWV in certain regions of the northern United States.
L. VanBlargan +5 more
semanticscholar +3 more sources