The Role of Host Cytoskeleton in Flavivirus Infection [PDF]
The family of flaviviruses is one of the most medically important groups of emerging arthropod-borne viruses. Host cell cytoskeletons have been reported to have close contact with flaviviruses during virus entry, intracellular transport, replication, and egress process, although many detailed mechanisms are still unclear.
Yue Zhang +4 more
openaire +2 more sources
Mechanism through which retrocyclin targets flavivirus multiplication [PDF]
Currently, there are no approved drugs for the treatment of flavivirus infection. Accordingly, we tested the inhibitory effects of the novel θ-defensin retrocyclin-101 (RC-101) against flavivirus infection, and investigated the mechanism underlying the ...
Guo, Jiao +9 more
core +1 more source
Pathogenesis of flavivirus infections: using and abusing the host cell.
M. Fernandez-Garcia +3 more
semanticscholar +3 more sources
Neutrophil Recruitment and Participation in Severe Diseases Caused by Flavivirus Infection
Neutrophils are first-line responders to infections and are recruited to target tissues through the action of chemoattractant molecules, such as chemokines. Neutrophils are crucial for the control of bacterial and fungal infections, but their role in the
Marina Alves Fontoura +2 more
doaj +1 more source
Regulation of Apoptosis during Flavivirus Infection [PDF]
Apoptosis is a type of programmed cell death that regulates cellular homeostasis by removing damaged or unnecessary cells. Its importance in host defenses is highlighted by the observation that many viruses evade, obstruct, or subvert apoptosis, thereby blunting the host immune response.
Toru Okamoto +6 more
openaire +3 more sources
Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure
Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research.
Nicole Marzan-Rivera +13 more
doaj +1 more source
Oculopathologic Findings in Flavivirus-Infected Gallinaceous Birds [PDF]
Using eye samples of nine 9-week-old experimentally West Nile virus (WNV)–infected red-legged partridges ( Alectoris rufa), time course of lesions and WNV antigen appearance in ocular structures were examined. In addition, eye samples of 6 red-legged partridges and 3 common pheasants ( Phasianus colchicus) naturally infected with Bagaza virus (BAGV ...
Gamino, V. +5 more
openaire +3 more sources
Are we prepared for emerging flaviviruses in Europe? Challenges for vaccination
Tick-borne encephalitis and West Nile fever are endemic flavivirus diseases in Europe. Climate change, virus evolution, and social factors may increase the risk of these flavivirus infections and may lead to the emergence of other flaviviruses in Europe ...
Patricia Kaaijk, Willem Luytjes
doaj +1 more source
Flying under the radar – impact and factors influencing asymptomatic DENV infections
The clinical outcome of DENV and other Flaviviruses infections represents a spectrum of severity that ranges from mild manifestations to severe disease, which can ultimately lead to death.
Paulo Henriques +7 more
doaj +1 more source
Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan +15 more
doaj +1 more source

