Cyclophilins and Their Roles in Hepatitis C Virus and Flavivirus Infections: Perspectives for Novel Antiviral Approaches [PDF]
Pathogens, 2021 Cyclophilins are cellular peptidyl-prolyl isomerases that play an important role in viral infections, with demonstrated roles in the replication of hepatitis C virus (HCV) and other viruses in the Flaviviridae family, such as dengue virus (DENV) and ...
Carla E. Gallardo-Flores +1 more
core +2 more sources
Presence of Segmented Flavivirus Infections in North America [PDF]
Emerg Infect Dis, 2020 Identifying viruses in synanthropic animals is necessary for understanding the origin of many viruses that can infect human hosts and developing strategies to prevent new zoonotic infections.
K. Vandegrift +7 more
semanticscholar +2 more sources
Trends in Flavivirus Infections in Japan [PDF]
Emerging Infectious Diseases, 2000 Although Japanese encephalitis has declined as an important cause of illness and death in Japan, infection with other flaviviruses has become a public health concern.
Ichiro Kurane +2 more
doaj +3 more sources
Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections [PDF]
Viruses, 2020 Zika virus (ZIKV), a mosquito-borne human flavivirus that causes microcephaly and other neurological disorders, has been a recent focus for the development of flavivirus vaccines and therapeutics. We report here a 4.0 Å resolution structure of the mature
M. Sevvana +12 more
semanticscholar +2 more sources
The role of γδ T cells in flavivirus infections: Insights into immune defense and therapeutic opportunities. [PDF]
PLoS Neglected Tropical Diseasesγδ T cells are a unique subset of unconventional T cells and an important component of the innate immune system. Unlike conventional αβ T cells, γδ T cells can respond rapidly during the early stages of infection, and their antigen recognition is not ...
Qi Li +7 more
doaj +2 more sources
Flavivirus Infection Associated with Cerebrovascular Events [PDF]
Viruses, 2020 Arthropod-borne viruses (arboviruses) of the genus Flavivirus are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hemorrhage, encephalitis and death.
Cássia F. Estofolete +6 more
openaire +4 more sources
A high-throughput and multiplex microsphere immunoassay based on non-structural protein 1 can discriminate three flavivirus infections [PDF]
PLoS Negl Trop Dis, 2019 The explosive spread of Zika virus (ZIKV) and associated complications in flavivirus-endemic regions underscore the need for sensitive and specific serodiagnostic tests to distinguish ZIKV, dengue virus (DENV) and other flavivirus infections.
J. Tyson +7 more
semanticscholar +2 more sources
Perturbation of Intracellular Cholesterol and Fatty Acid Homeostasis During Flavivirus Infections [PDF]
Front Immunol, 2018 Cellular lipid homeostasis is maintained through an intricately linked array of anabolic and catabolic pathways. Upon flavivirus infections, these are significantly altered: on the one hand, these viruses can co-opt lipid metabolic pathways to generate ...
J. Pombo, Sumana Sanyal
semanticscholar +2 more sources
Host genetic control of mosquito-borne Flavivirus infections [PDF]
Mamm Genome, 2018 Flaviviruses are arthropod-borne viruses, several of which represent emerging or re-emerging pathogens responsible for widespread infections with consequences ranging from asymptomatic seroconversion to severe clinical diseases and congenital ...
Caroline Manet +5 more
semanticscholar +2 more sources
Neurological disease caused by flavivirus infections
Microbiology Australia, 2018 The Flavivirus genus contains dozens of species with varying geographical distributions. Most flavivirus infections in humans are asymptomatic or manifest as a non-specific febrile illness, sometimes accompanied by rash or arthralgia. Certain species are
Tristan Gibbs, David J Speers
openaire +2 more sources