Results 11 to 20 of about 3,670,778 (207)
Astrocytes in Flavivirus Infections [PDF]
International Journal of Molecular Sciences, 2019 Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge
M. Potokar +2 more
semanticscholar +7 more sources
The Complement System in Flavivirus Infections [PDF]
Frontiers in Microbiology, 2017 The incidence of flavivirus infections has increased dramatically in recent decades in tropical and sub-tropical climates worldwide, affecting hundreds of millions of people each year.
Jonas N. Conde +3 more
semanticscholar +6 more sources
A glance at subgenomic flavivirus RNAs and microRNAs in flavivirus infections [PDF]
Virology Journal, 2016 The family Flaviviridae comprises a wide variety of viruses that are distributed worldwide, some of which are associated with high rates of morbidity and mortality. There are neither vaccines nor antivirals for most flavivirus infections, reinforcing the
L. Bavia +3 more
semanticscholar +6 more sources
Cellular Targets for the Treatment of Flavivirus Infections [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Classical antiviral therapy targets viral functions, mostly viral enzymes or receptors. Successful examples include precursor herpesvirus drugs, antiretroviral drugs that target reverse transcriptase and protease, influenza virus directed compounds as ...
Mohammad Khalid Zakaria +2 more
doaj +6 more sources
The Role of NS1 Protein in the Diagnosis of Flavivirus Infections [PDF]
Viruses, 2023 Nonstructural protein 1 (NS1) is a glycoprotein among the flavivirus genus. It is found in both membrane-associated and soluble secreted forms, has an essential role in viral replication, and modulates the host immune response.
Ron Fisher +3 more
semanticscholar +5 more sources
Antibody Responses to Zika Virus Infections in Environments of Flavivirus Endemicity
Vaccine Journal, 2017 Zika virus (ZIKV) infections occur in areas where dengue virus (DENV), West Nile virus (WNV), yellow fever virus (YFV), and other viruses of the genus Flavivirus cocirculate. The envelope (E) proteins of these closely related flaviviruses induce specific
Sarah L. Keasey +8 more
semanticscholar +4 more sources
Neuroinvasive flavivirus infections [PDF]
Reviews in Medical Virology, 2012 SUMMARYFlaviviruses, including Dengue, West Nile, Japanese encephalitis, and Tick‐borne encephalitis virus, are major emerging human pathogens, affecting millions of individuals worldwide. Many clinically important flaviviruses elicit CNS diseases in infected hosts, including traditional “hemorrhagic” viruses, such as Dengue. This review focuses on the
G. Sips, J. Wilschut, J. Smit
semanticscholar +6 more sources
Molecular and Cellular Mechanisms Underlying Neurologic Manifestations of Mosquito-Borne Flavivirus Infections [PDF]
Viruses, 2023 Flaviviruses are a family of enveloped viruses with a positive-sense RNA genome, transmitted by arthropod vectors. These viruses are known for their broad cellular tropism leading to infection of multiple body systems, which can include the central ...
Britanie M. Blackhurst, Kristen E. Funk
semanticscholar +2 more sources
Flaviviruses as agents of childhood central nervous system infections in Brazil [PDF]
New Microbes and New Infections, 2019 Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj +4 more sources
Flavivirus: From Structure to Therapeutics Development
Life, 2021 Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao +6 more
doaj +2 more sources