Results 11 to 20 of about 30,996 (190)

Enzyme-linked immunosorbent assays using virus-like particles containing mutations of conserved residues on envelope protein can distinguish three flavivirus infections [PDF]

open access: yesEmerging Microbes and Infections, 2020
The recent outbreaks of Zika virus (ZIKV) in flavivirus-endemic regions highlight the need for sensitive and specific serological tests. Previously we and others reported key fusion loop (FL) residues and/or BC loop (BCL) residues on dengue virus (DENV ...
Wen-Yang Tsai   +2 more
exaly   +4 more sources

Astrocytes in Flavivirus Infections [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
Virus infections of the central nervous system (CNS) can manifest in various forms of inflammation, including that of the brain (encephalitis) and spinal cord (myelitis), all of which may have long-lasting deleterious consequences. Although the knowledge of how different viruses affect neural cells is increasing, understanding of the mechanisms by ...
Robert Zorec   +2 more
exaly   +6 more sources

The Complement System in Flavivirus Infections [PDF]

open access: yesFrontiers in Microbiology, 2017
The incidence of flavivirus infections has increased dramatically in recent decades in tropical and sub-tropical climates worldwide, affecting hundreds of millions of people each year. The Flaviviridae family includes dengue, West Nile, Zika, Japanese encephalitis, and yellow fever viruses that are typically transmitted by mosquitoes or ticks, and ...
Mohana-Borges R   +2 more
exaly   +5 more sources

A glance at subgenomic flavivirus RNAs and microRNAs in flavivirus infections. [PDF]

open access: yesVirol J, 2016
The family Flaviviridae comprises a wide variety of viruses that are distributed worldwide, some of which are associated with high rates of morbidity and mortality. There are neither vaccines nor antivirals for most flavivirus infections, reinforcing the importance of research on different aspects of the viral life cycle.
Bavia L   +3 more
europepmc   +7 more sources

Flaviviruses as agents of childhood central nervous system infections in Brazil [PDF]

open access: yesNew Microbes and New Infections, 2019
Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj   +5 more sources

Flavivirus: From Structure to Therapeutics Development [PDF]

open access: yesLife, 2021
Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao   +6 more
doaj   +2 more sources

An mRNA Vaccine Protects Mice against Multiple Tick-Transmitted Flavivirus Infections [PDF]

open access: yesCell Reports, 2018
Summary: Powassan virus (POWV) is an emerging tick-transmitted flavivirus that circulates in North America and Russia. Up to 5% of deer ticks now test positive for POWV in certain regions of the northern United States. Although POWV infections cause life-
Theodore Pierson   +2 more
exaly   +5 more sources

Neuroinvasive flavivirus infections [PDF]

open access: yesReviews in Medical Virology, 2011
SUMMARYFlaviviruses, including Dengue, West Nile, Japanese encephalitis, and Tick‐borne encephalitis virus, are major emerging human pathogens, affecting millions of individuals worldwide. Many clinically important flaviviruses elicit CNS diseases in infected hosts, including traditional “hemorrhagic” viruses, such as Dengue. This review focuses on the
Gregorius J, Sips   +2 more
openaire   +4 more sources

Trends in Flavivirus Infections in Japan [PDF]

open access: yesEmerging Infectious Diseases, 2000
Although Japanese encephalitis has declined as an important cause of illness and death in Japan, infection with other flaviviruses has become a public health concern.
Ichiro Kurane   +2 more
doaj   +3 more sources

Flavivirus Infection Associated with Cerebrovascular Events [PDF]

open access: yesViruses, 2020
Arthropod-borne viruses (arboviruses) of the genus Flavivirus are distributed globally and cause significant human disease and mortality annually. Flavivirus infections present a spectrum of clinical manifestations, ranging from asymptomatic to severe manifestations, including hemorrhage, encephalitis and death.
Cássia F. Estofolete   +6 more
openaire   +5 more sources

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