Results 51 to 60 of about 30,996 (190)

Imported Arbovirus Infections in Canada 1974-89

Canadian Journal of Infectious Diseases, 1991
From 1974 to 1989, sera from symptomatic patients with histories of recent travel outside Canada were tested for antibodies to several arboviruses, principally of the alphavirus and flavivirus families.
Harvey Artsob, Leslie Spence
doaj   +1 more source

Bagaza Virus in Partridges and Pheasants, Spain, 2010

Emerging Infectious Diseases, 2011
In September 2010, an unusually high number of wild birds (partridges and pheasants) died in Cádiz in southwestern Spain. Reverse transcription PCR and virus isolation detected flavivirus infections.
Montserrat Agüero, Jovita Fernández-Pinero, Dolores Buitrago, Azucena Sánchez, Maia Elizalde, Elena San Miguel, Ruben Villalba, Francisco Llorente, Miguel Ángel Jiménez-Clavero   +8 more
doaj   +1 more source

Impact of flavivirus vaccine-induced immunity on primary Zika virus antibody response in humans.

PLoS Neglected Tropical Diseases, 2020
BackgroundZika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g.
Stefan Malafa, Iris Medits, Judith H Aberle, Stephan W Aberle, Denise Haslwanter, Georgios Tsouchnikas, Silke Wölfel, Kristina L Huber, Elena Percivalle, Pascal Cherpillod, Melissa Thaler, Lena Roßbacher, Michael Kundi, Franz X Heinz, Karin Stiasny   +14 more
doaj   +1 more source

Risk Factors for Exposure of Wild Birds to West Nile Virus in A Gradient of Wildlife-Livestock Interaction

Pathogens, 2023
West Nile virus (WNV) transmission rate is shaped by the interaction between virus reservoirs and vectors, which may be maximized in farm environments.
Laia Casades-Martí, Rocío Holgado-Martín, Pilar Aguilera-Sepúlveda, Francisco Llorente, Elisa Pérez-Ramírez, Miguel Ángel Jiménez-Clavero, Francisco Ruiz-Fons   +6 more
doaj   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Pooled prevalence estimates of comorbidities in severe and non-severe cases of flavivirus infections dengue fever and West Nile virus. [PDF]

, 2018
Pooled prevalence estimates of comorbidities in severe and non-severe cases of flavivirus infections dengue fever and West Nile virus.
Arrani Senthinathan (5497523), Mikayla Plishka (5497541), Russanthy Velummailum (5497529), Sahar Yaghoubi (5497532), Denitsa Vasileva (5497535), Paul Arora (141025), Marcel Soosaipillai (5497544), Emma Ostermeier (5497538), Alaa Badawi (521535), Seung Gwan Ryoo (5497526)   +9 more
core   +1 more source

Sustainable, three-component, one-pot procedure to obtain active anti-flavivirus agents [PDF]

, 2021
The mosquito-borne viruses belonging to the genus Flavivirus such as Dengue virus (DENV) and Zika virus (ZIKV) cause human infections ranging from mild flu-like symptoms to hemorrhagic fevers, hepatitis, and neuropathies. To date, there are vaccines only
Violetta Cecchetti, Manfroni, G, Maria Sole Burali, Burali, MS, Kitti Wing Ki Chan, Gwee, CP, Vasudevan, SG, Chin Piaw Gwee, Oriana Tabarrini, Massari, S, Barreca, ML, Subhash G. Vasudevan, Stefano Sabatini, Maria Letizia Barreca, Tommaso Felicetti, Sylvie Alonso, Cecchetti, V, Alonso, S, Tabarrini, O, Ki Chan, KW, Giuseppe Manfroni, Felicetti, T, Serena Massari, Sabatini, S   +23 more
core   +1 more source

Detection of antibodies against flavivirus over time in wild non-human primates from the lowlands of Costa Rica.

PLoS ONE, 2019
Two-hundred-nine free ranging non-human primates from 31 locations throughout Costa Rica were captured and released between 1993 and 2012, and blood samples, sera or plasma were collected, to detect antigens and antibodies, and so assess the distribution
Gaby Dolz, Andrea Chaves, Gustavo A Gutiérrez-Espeleta, Edgar Ortiz-Malavasi, Sofía Bernal-Valle, Marco Vinicio Herrero   +5 more
doaj   +1 more source

RNF138‐Mediated Ubiquitination and Degradation of NS5 Restricts Tick‐Borne Encephalitis Virus Infection

Advanced Science, EarlyView.
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun, Weijing Yang, Hao Zhou, Shuai Li, Xin Jiang, Jianyang Gu, Wenyan Zhang   +6 more
wiley   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source