Results 11 to 20 of about 26,407 (220)

Aquatic Flaviviruses [PDF]

open access: yesJournal of Virology, 2022
Flaviviruses are positive-sense single-stranded RNA viruses, including some well-known human pathogens such as Zika, dengue, and yellow fever viruses, which are primarily associated with mosquito and tick vectors. The vast majority of flavivirus research has focused on terrestrial environments; however, recent findings indicate that a range of ...
Megan J. Lensink   +2 more
openaire   +4 more sources

Flaviviruses in AntiTumor Therapy

open access: yesViruses, 2023
Oncolytic viruses offer a promising approach to tumor treatment. These viruses not only have a direct lytic effect on tumor cells but can also modify the tumor microenvironment and activate antitumor immunity. Due to their high pathogenicity, flaviviruses have often been overlooked as potential antitumor agents.
Alina S. Nazarenko   +7 more
openaire   +4 more sources

Tick-Borne Flaviviruses and the Type I Interferon Response

open access: yesViruses, 2018
Flaviviruses are globally distributed pathogens causing millions of human infections every year. Flaviviruses are arthropod-borne viruses and are mainly transmitted by either ticks or mosquitoes.
Richard Lindqvist   +2 more
doaj   +2 more sources

Lipid Interactions Between Flaviviruses and Mosquito Vectors

open access: yesFrontiers in Physiology, 2021
Mosquito-borne flaviviruses, such as dengue (DENV), Zika (ZIKV), yellow fever (YFV), West Nile (WNV), and Japanese encephalitis (JEV) viruses, threaten a large part of the human populations.
Thomas Vial   +5 more
doaj   +2 more sources

Flaviviruses as agents of childhood central nervous system infections in Brazil [PDF]

open access: yesNew Microbes and New Infections, 2019
Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj   +4 more sources

Biochemistry and Molecular Biology of Flaviviruses [PDF]

open access: yesChemical Reviews, 2018
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile, yellow fever, and Zika viruses, are critically important human pathogens that sicken a staggeringly high number of humans every year. Most of these pathogens are transmitted by mosquitos, and not surprisingly, as the earth warms and human populations grow and move,
Nicholas J. Barrows   +10 more
openaire   +4 more sources

RNF138-Mediated Ubiquitination and Degradation of NS5 Restricts Tick-Borne Encephalitis Virus Infection. [PDF]

open access: yesAdv Sci (Weinh)
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Sun J   +6 more
europepmc   +2 more sources

Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses [PDF]

open access: yes, 2022
The genus Flavivirus includes pathogenic tick- and mosquito-borne flaviviruses as well as non-pathogenic insect-specific flaviviruses (ISFVs). Phylogenetic analysis based on whole amino acid sequences has indicated that lineage II ISFVs have similarities
Tabata, Koshiro   +11 more
core   +1 more source

From Capsids to Complexes: Expanding the Role of TRIM5α in the Restriction of Divergent RNA Viruses and Elements

open access: yesViruses, 2021
An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population ...
Kevin M. Rose   +6 more
doaj   +1 more source

Quercetin Inhibits Hsp70 Blocking of Bovine Viral Diarrhea Virus Infection and Replication in the Early Stage of Virus Infection

open access: yesViruses, 2022
Bovine viral diarrhea virus (BVDV), a positive-strand RNA virus of the genus Pestivirus in the Flaviviridae family, is the causative agent of viral diarrheal disease in bovine.
Nannan Chen   +10 more
doaj   +1 more source

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