Results 11 to 20 of about 33,545 (217)
The Flavivirus NS3 Protein: Its Multifaceted Roles and Therapeutic Potential. [PDF]
J Med VirolAbstract Mosquito‐borne flaviviruses are important human pathogenic viruses and can cause an array of symptoms ranging from asymptomatic to mild illness but can progress to severe disease conditions. Prominent members of the family Flaviviridae include Dengue virus, Zika virus, and West Nile virus, whose spread has increased globally due to the ...
Lee H, Cho H, Gack MU.
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Journal of Virology, 2022 Flaviviruses are positive-sense single-stranded RNA viruses, including some well-known human pathogens such as Zika, dengue, and yellow fever viruses, which are primarily associated with mosquito and tick vectors. The vast majority of flavivirus research has focused on terrestrial environments; however, recent findings indicate that a range of ...
Megan J. Lensink +2 more
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A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis [PDF]
, 2017 The structural flexibility or 'breathing' of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium.
Diamond, Michael S +4 more
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Viruses, 2022 The Kunjin strain of West Nile virus (WNVKUN) is a mosquito-transmitted flavivirus that can infect farmed saltwater crocodiles in Australia and cause skin lesions that devalue the hides of harvested animals.
Nina Kurucz +15 more
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Application of DNA Replicons in Gene Therapy and Vaccine Development
Pharmaceutics, 2023 DNA-based gene therapy and vaccine development has received plenty of attention lately. DNA replicons based on self-replicating RNA viruses such as alphaviruses and flaviviruses have been of particular interest due to the amplification of RNA transcripts
Kenneth Lundstrom
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Current Biology, 2016 What do Zika, Dengue and West Nile viruses have in common? All are members of a family of viruses called the Flaviviruses. Here, Sonja Best lays out the essentials of this group of significant human pathogens.
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Tick-Borne Flaviviruses and the Type I Interferon Response
Viruses, 2018 Flaviviruses are globally distributed pathogens causing millions of human infections every year. Flaviviruses are arthropod-borne viruses and are mainly transmitted by either ticks or mosquitoes.
Richard Lindqvist +2 more
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Tetraspanins as Potential Therapeutic Candidates for Targeting Flaviviruses
Frontiers in Immunology, 2021 Tetraspanin family of proteins participates in numerous fundamental signaling pathways involved in viral transmission, virus-specific immunity, and virus-mediated vesicular trafficking.
Waqas Ahmed +4 more
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Uirusu, 2011 Family Flaviviridae genus flavivirus contains numerous pathogenic viruses such as Japanese encephalitis virus, dengue virus, West Nile virus, etc, which cause public health problems in the world. Since many mammals and birds can act as amplifying hosts and reservoir hosts in nature and those viruses are transmitted by haematophagous mosquitoes or ticks,
Tomohiro, Ishikawa, Eiji, Konishi
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Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines
Frontiers in Immunology, 2022 The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan +15 more
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