Results 41 to 50 of about 25,105 (218)

Replicon RNA Viral Vectors as Vaccines

open access: yesVaccines, 2016
Single-stranded RNA viruses of both positive and negative polarity have been used as vectors for vaccine development. In this context, alphaviruses, flaviviruses, measles virus and rhabdoviruses have been engineered for expression of surface protein ...
Kenneth Lundstrom
doaj   +1 more source

Detection of mosquito-only flaviviruses in Europe [PDF]

open access: yes, 2012
The genus Flavivirus, family Flaviviridae, includes a number of important arthropod-transmitted human pathogens such as dengue viruses, West Nile virus, Japanese encephalitis virus and yellow fever virus.
Bonilauri, P.   +38 more
core   +1 more source

Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses [PDF]

open access: yes, 2023
Flaviviruses are present on every continent and cause significant morbidity and mortality. In many instances, severe cases of infection with flaviviruses involve the invasion of and damage to the central nervous system (CNS). Currently, there are several
Harding, Alfred T.   +3 more
core   +1 more source

Zika Virus Vaccines: Challenges and Perspectives

open access: yesVaccines, 2018
Zika virus is an arbovirus that has rapidly spread within the Americas since 2014, presenting a variety of clinical manifestations and neurological complications resulting in congenital malformation, microcephaly, and possibly, in male infertility. These
Raquel das Neves Almeida   +3 more
doaj   +1 more source

Development of genus-specific universal primers for the detection of flaviviruses

open access: yesVirology Journal, 2021
Background Flaviviruses are representative arboviruses carried by arthropods and/or vertebrates; these viruses can pose a public health concern in many countries. By contrast, it is known that a novel virus group called insect-specific flaviviruses (ISFs)
Tomo Daidoji   +9 more
doaj   +1 more source

Flavivirus cross-reactivity: Insights into e-protein conservancy, pre-existing immunity, and co-infection

open access: yesThe Microbe
Flaviviruses are enveloped, single-stranded RNA viruses that are largely arthropod-borne, circulating globally and infecting up to 400 million people annually.
Abdulbariu Ogirima Uhuami   +3 more
doaj   +1 more source

Anti-flavi: A Web Platform to Predict Inhibitors of Flaviviruses Using QSAR and Peptidomimetic Approaches

open access: yesFrontiers in Microbiology, 2018
Flaviviruses are arboviruses, which comprises more than 70 viruses, covering broad geographic ranges, and responsible for significant mortality and morbidity globally. Due to the lack of efficient inhibitors targeting flaviviruses, the designing of novel
Akanksha Rajput, Manoj Kumar
doaj   +1 more source

Presence of Segmented Flaviviruses in Wild Rodents, Pennsylvania, USA

open access: yesEmerging Infectious Diseases, 2020
Identifying viruses in synanthropic animals is necessary for understanding the origin of many viruses that can infect human hosts and developing strategies to prevent new zoonotic infections.
Arvind Kumar   +7 more
doaj   +1 more source

Rapid Generation of Recombinant Flaviviruses Using Circular Polymerase Extension Reaction [PDF]

open access: yes, 2023
The genus Flavivirus is a group of arthropod-borne single-stranded RNA viruses, which includes important human and animal pathogens such as Japanese encephalitis virus (JEV), Zika virus (ZIKV), Dengue virus (DENV), yellow fever virus (YFV), West Nile ...
Guo-Qing Xiong   +16 more
core   +1 more source

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection

open access: yesEmerging Infectious Diseases, 2017
Cross-reactive antibodies elicited by dengue virus (DENV) infection might affect Zika virus infection and confound serologic tests. Recent data demonstrate neutralization of Zika virus by monoclonal antibodies or human serum collected early after DENV ...
Matthew H. Collins   +7 more
doaj   +1 more source

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