Results 51 to 60 of about 26,407 (220)

Flaviviruses of public health concern in South Africa: Present and future threats

open access: yesSouthern African Journal of Infectious Diseases
Background: The resurgence and widespread transmission of flaviviruses over the past few decades are particularly concerning. Aim: This review discusses the structure, aetiology, transmission, detection, diagnosis and prevention strategies for ...
Angela Sibanda-Makuvise   +2 more
doaj   +1 more source

The thermal stability of yellow fever vaccines

open access: yesMemorias do Instituto Oswaldo Cruz, 1990
The assessment of yellow fever vaccine thermostability both in lyophilized form and after reconstitution were analyzed. Two commercial yellow fever vaccines were assayed for their thermal stability. Vaccines were exposed to test temperatures in the range
Ricardo Ishak, Colin R. Howard
doaj   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

open access: yesAdvanced Science, EarlyView.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang   +20 more
wiley   +1 more source

Virucidal Approaches for Hemorrhagic Fever Viruses

open access: yesViruses
We have reviewed the primary literature on the virucidal efficacy of microbicidal active ingredients, formulated microbicides, and physical inactivation approaches (heat, irradiation) for hemorrhagic fever viruses (HFVs) (arenaviruses, filoviruses ...
Raymond W. Nims, M. Khalid Ijaz
doaj   +1 more source

Encephalitis caused by flaviviruses [PDF]

open access: yesQJM, 2012
The genus Flavivirus, family Flaviviridae, contains some of the most important arboviral pathogens of man. The genus includes several aetiological agents of encephalitis, the most significant being Japanese encephalitis virus, West Nile virus and tick-borne encephalitis virus.
L, Turtle, M J, Griffiths, T, Solomon
openaire   +2 more sources

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

Phylogenomic characterization of flaviviruses [PDF]

open access: yes, 2019
Background: The occurrences of global viral pandemics have been rising as increased travel between distant countries has introduced previously endemic viruses to new envi-ronments.
Truong, Phuoc
core  

Structural Asymmetry of Flaviviruses

open access: yes, 2019
Flaviviruses are enveloped, positive-strand RNA viruses that are spread by mosquitoes and ticks and can cause serious disease in humans. Flavivirus virions undergo extensive structural changes during their life cycle, including during maturation and ...
Therkelsen, Matthew D
core   +2 more sources

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

open access: yesAdvanced Science, EarlyView.
ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo   +9 more
wiley   +1 more source

Antibodies to flaviviruses in wild ducks captured in Hokkaido, Japan: Risk assessment of invasive flaviviruses [PDF]

open access: yes, 2009
ArticleRecently, the distribution of Japanese encephalitis virus (JEV) and West Nile virus (WNV) has expanded into new territories. The invasion of WNV into Japan is of great concern.
Osa, Yuichi   +5 more
core   +1 more source

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