Results 61 to 70 of about 26,784 (178)

Distribution of PRNT₉₀ titers for 7 flaviviruses among 30 black howlers positive for several flaviviruses without four-fold differences (undetermined flavivirus).

, 2017
Distribution of PRNT90 titers for 7 flaviviruses among 30 black howlers positive for several flaviviruses without four-fold differences (undetermined flavivirus).
Martín M. Kowalewski (3740704), Delia A. Enría (3740689), Gabriel E. Zunino (3740698), Victoria C. Luppo (3740686), María A. Morales (3740692), Gladys E. Calderón (3740683), Silvana C. Levis (3740701), Cintia M. Fabbri (3740695)   +7 more
core   +1 more source

Membranous Replication Factories Induced by Plus-Strand RNA Viruses

Viruses, 2014
In this review, we summarize the current knowledge about the membranous replication factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of these complex membrane rearrangements, because this topic emerged in the ...
Inés Romero-Brey, Ralf Bartenschlager
doaj   +1 more source

Human Pegivirus Encephalitis With Brain Detection and Response to Sofosbuvir Ledipasvir

Annals of Clinical and Translational Neurology, Volume 13, Issue 10, Page 2138-2142, October 2026.
ABSTRACT Human pegivirus (HPgV‐1) has been associated with severe encephalomyelitis in immunocompromised patients. Its neurological spectrum remains poorly defined. We report a slowly progressive encephalitis in a person living with well‐controlled HIV, characterized by white matter abnormalities and inflammatory cerebrospinal fluid (CSF). HPgV RNA was
Antoine Moulignier, Françoise Heran, Francis Lallemand, Pierre Bourdillon   +3 more
wiley   +1 more source

Targeted Degradation of Picornaviral 3C Protease via PROTACs Confers High Barrier to Viral Resistance and Broad‐Spectrum Antiviral Activity

Advanced Science, Volume 13, Issue 57, 14 October 2026.
This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng, Junyu Chen, Yingyue Pang, Yuanyuan Zhang, Siqian Chen, Guoliang You, Xiaoman Tian, Zhongxin Xu, Jing Wang, Luqing Shang   +9 more
wiley   +1 more source

CpG usages of flaviviruses that infect different types of hosts.

, 2013
CpG usages of flaviviruses that infect different types of hosts.
Shuqin Ji (461903), Xiaofei Cheng (90802), Yuqiang Sun (317145), Nasar Virk (461902), Xiaoyun Wu (179670), Wei Chen (23863), Shuxian Ji (461904)   +6 more
core   +1 more source

Computation and Structure‐Guided Arginine Scanning Engineers a Hyperactive AP Endonuclease for Multiplex Viral RNA Sensing

Advanced Science, Volume 13, Issue 58, 19 October 2026.
Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang, Ting Wu, Feizuo Wang, Boyang Wang, Xin Yu Wong, Senfeng Zhang, Shengsheng Ma, Yao Liu, Fangyao Yao, Zhifeng Zeng, Siyuan Yang, Kunming Liu, Qi Wang, Yilong Wang, Yunxiang Zang, Xiaolong Wang, Xingxu Huang, Shao Li, Quanquan Ji, Tao Hu, Chunyi Hu   +20 more
wiley   +1 more source

Comparative analysis of the taxonomic classification criteria for a number of groups of pathogenic DNA and RNA viruses based on genomic data

Вопросы вирусологии
The basis for criteria of the taxonomic classification of DNA and RNA viruses based on data of the genomic sequencing are viewed in this review. The genomic sequences of viruses, which have genome represented by double-stranded DNA (orthopoxviruses as ...
Tatiana E. Sizikova, Vitaliy N. Lebedev, Sergey V. Borisevich   +2 more
doaj   +1 more source

FAM134B Restricts African Swine Fever Virus Capsid Assembly via Reticulophagy and Its Antiviral Activity is Antagonized by the Viral Virulence‐Associated Factor pMGF300‐2R

Advanced Science, Volume 13, Issue 58, 19 October 2026.
ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo, Jing Zhang, Ruojia Huang, Xianfeng Zhang, Lian‐Feng Li, Jing Lan, Zhanhao Lu, Yuan Sun, Tao Wang, Hua‐Ji Qiu   +9 more
wiley   +1 more source

Cross‐Reactive Neutralizing Antibodies Between ZIKV and DENV May Exhibit Serotype Specificity

Biotechnology Journal, Volume 21, Issue 10, October 2026.
Graphical Abstract and Lay Summary Immunization with ZIKV protein extract may induce serotype‐specific neutralizing antibodies against DENV. ABSTRACT Dengue virus (DENV) and Zika virus (ZIKV) are public health threats, causing substantial morbidity and mortality worldwide.
Lucimeire Antonelli da Silveira, Djairo Pastor Saavedra, Isabela Cinquini Junqueira, Jefferson do Carmo Dietz, Cristina Rodrigues de Oliveira, Leonardo Lopes‐Luz, Lorena Carvalho de Souza Chaves, Bergmann Morais Ribeiro   +7 more
wiley   +1 more source

Insights Into the Role of Platelet Factor 4 in Neurodegenerative Diseases

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
This review summarizes potential functions of platelet factor 4 (PF4) in neurodegenerative diseases (NDs) and discusses its promise as both a biomarker and a therapeutic target. Further elucidation of PF4 signaling pathways may provide new insights into disease mechanisms and uncover novel opportunities for targeted interventions in NDs.
Qi Tian, Yanji Tong, Fang Yu, Xiaoming Hu   +3 more
wiley   +1 more source