Results 21 to 30 of about 46,284 (171)

Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure

open access: yesiScience, 2022
Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research.
Nicole Marzan-Rivera   +13 more
doaj   +1 more source

A targeted approach with nanopore sequencing for the universal detection and identification of flaviviruses

open access: yesScientific Reports, 2021
Nucleic acid test (NAT), most typically quantitative PCR, is one of the standard methods for species specific flavivirus diagnosis. Semi-comprehensive NATs such as pan-flavivirus PCR which covers genus Flavivirus are also available; however, further ...
Patrick Reteng   +12 more
doaj   +1 more source

30 years of fatal dengue cases in Brazil: a review

open access: yesBMC Public Health, 2019
Background Over the last 30 years, extensive dengue epidemics have occurred in Brazil, characterized by emergences and re-emergences of different serotypes, a change in the epidemiological profile and an increase in the number of severe and fatal cases ...
Priscila Conrado Guerra Nunes   +5 more
doaj   +1 more source

Potential Role of Flavivirus NS2B-NS3 Proteases in Viral Pathogenesis and Anti-flavivirus Drug Discovery Employing Animal Cells and Models: A Review

open access: yesViruses, 2021
Flaviviruses are known to cause a variety of diseases in humans in different parts of the world. There are very limited numbers of antivirals to combat flavivirus infection, and therefore new drug targets must be explored.
Abdul Wahaab   +8 more
doaj   +1 more source

First detection and molecular characterization of a DENV‐1/DENV‐4 co‐infection during an epidemic in Rio de Janeiro, Brazil

open access: yesClinical Case Reports, 2018
Key Clinical Message In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide ...
Fernanda de Bruycker‐Nogueira   +5 more
doaj   +1 more source

Generation and Implementation of Reporter BHK-21 Cells for Live Imaging of Flavivirus Infection

open access: yesBio-Protocol, 2021
The genus Flavivirus within the family Flaviviridae includes many viral species of medical importance, such as yellow fever virus (YFV), Zika virus (ZIKV), and dengue virus (DENV), among others.
Jorge Arias-Arias   +1 more
doaj   +1 more source

Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review

open access: yesAsian Pacific Journal of Tropical Medicine, 2023
Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin   +3 more
doaj   +1 more source

Seeking Flavivirus Cross-Protective Immunity

open access: yesFrontiers in Immunology, 2019
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Lorrany dos Santos Franco   +4 more
doaj   +1 more source

Usutski virus: novi Flavivirus u Hrvatskoj [Usutu virus: a novel flavivirus in Croatia] [PDF]

open access: yes, 2015
Usutu virus (USUV) belongs to the family Flaviviridae, genus Flavivirus, Japanese encephalitis serocomplex. The virus was discovered in 1959 in South Africa and has emerged since 1996 causing epizootics with high avian mortality in Europe. The importance
Mlinarić-Galinović, Gordana   +3 more
core   +1 more source

A Perspective on Current Flavivirus Vaccine Development: A Brief Review

open access: yesViruses, 2023
The flavivirus genus contains several clinically important pathogens that account for tremendous global suffering. Primarily transmitted by mosquitos or ticks, these viruses can cause severe and potentially fatal diseases ranging from hemorrhagic fevers ...
Sudip Kumar Dutta, Thomas Langenburg
doaj   +1 more source

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