Results 21 to 30 of about 45,492 (218)

Role of nonstructural protein NS2A in flavivirus assembly [PDF]

, 2008
Flavivirus nonstructural (NS) proteins are involved in RNA replication and modulation of the host antiviral response; however, evidence is mounting that some NS proteins also have essential roles in virus assembly.
Pijlman, G.P., Leung, J.Y., Khromykh, A.A., Hyde, J., Kondratieva, N., Mackenzie, J.M.   +5 more
core   +1 more source

Yellow fever outbreak, Imatong, southern Sudan. [PDF]

, 2004
In May 2003, the World Health Organization received reports about a possible outbreak of a hemorrhagic disease of unknown cause in the Imatong Mountains of southern Sudan.
Sang, Rosemary C, Victor O. Ofula, Onyango, Clayton O, Ofula, Victor O, Rodney L. Coldren, Robert Swanepoel, Coldren, Rodney L, Burt, Felicity J, Kevin M. De Cock, Rosemary C. Sang, Okoth, Fredrick A, Tukei, Peter M, Samson L. Konongoi, Abdourahmane Sow, Peter M. Tukei, De Cock, Kenin M, Waters, Norman C, Felicity J. Burt, Sow, Abourahmane, Norman C. Waters, Clayton O. Onyango, Fredrick A. Okoth, Konongoi, Sanson L, Clayton O. Onyango, Swanepoel, Robert   +24 more
core   +1 more source

Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure

iScience, 2022
Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research.
Nicole Marzan-Rivera, Crisanta Serrano-Collazo, Lorna Cruz, Petraleigh Pantoja, Alexandra Ortiz-Rosa, Teresa Arana, Melween I. Martinez, Armando G. Burgos, Chiara Roman, Loyda B. Mendez, Elizabeth Geerling, Amelia K. Pinto, James D. Brien, Carlos A. Sariol   +13 more
doaj   +1 more source

Phylogeny of the Genus Flavivirus [PDF]

Journal of Virology, 1998
ABSTRACT We undertook a comprehensive phylogenetic study to establish the genetic relationship among the viruses of the genus Flavivirus and to compare the classification based on molecular phylogeny with the existing serologic method.
G, Kuno, G J, Chang, K R, Tsuchiya, N, Karabatsos, C B, Cropp   +4 more
openaire   +3 more sources

Culex flavivirus infection in a Culex pipiens mosquito colony and its effects on vector competence for Rift Valley fever phlebovirus

Parasites & Vectors, 2018
Background Rift Valley fever is a mosquito-borne zoonotic disease that affects domestic ruminants and humans. Culex flavivirus is an insect-specific flavivirus that naturally exists in field mosquito populations. The influence of Culex flavivirus on Rift
Sandra Talavera, Lotty Birnberg, Ana I. Nuñez, Francesc Muñoz-Muñoz, Ana Vázquez, Núria Busquets   +5 more
doaj   +1 more source

30 years of fatal dengue cases in Brazil: a review

BMC Public Health, 2019
Background Over the last 30 years, extensive dengue epidemics have occurred in Brazil, characterized by emergences and re-emergences of different serotypes, a change in the epidemiological profile and an increase in the number of severe and fatal cases ...
Priscila Conrado Guerra Nunes, Regina Paiva Daumas, Juan Camilo Sánchez-Arcila, Rita Maria Ribeiro Nogueira, Marco Aurélio Pereira Horta, Flávia Barreto dos Santos   +5 more
doaj   +1 more source

Neuroinvasive flavivirus infections [PDF]

Reviews in Medical Virology, 2011
SUMMARYFlaviviruses, including Dengue, West Nile, Japanese encephalitis, and Tick‐borne encephalitis virus, are major emerging human pathogens, affecting millions of individuals worldwide. Many clinically important flaviviruses elicit CNS diseases in infected hosts, including traditional “hemorrhagic” viruses, such as Dengue. This review focuses on the
Gregorius J, Sips, Jan, Wilschut, Jolanda M, Smit   +2 more
openaire   +2 more sources

Mechanism through which retrocyclin targets flavivirus multiplication [PDF]

, 2021
Currently, there are no approved drugs for the treatment of flavivirus infection. Accordingly, we tested the inhibitory effects of the novel θ-defensin retrocyclin-101 (RC-101) against flavivirus infection, and investigated the mechanism underlying the ...
Guo, Jiao, Sun, Lingling, Wang, Wei, Yuan, Weirong, Garzino-Demo, Alfredo, Liu, Yang, Lu, Wuyuan, Jia, Xiaoying, Xiao, Gengfu, Zhou, Minmin   +9 more
core   +1 more source

A targeted approach with nanopore sequencing for the universal detection and identification of flaviviruses

Scientific Reports, 2021
Nucleic acid test (NAT), most typically quantitative PCR, is one of the standard methods for species specific flavivirus diagnosis. Semi-comprehensive NATs such as pan-flavivirus PCR which covers genus Flavivirus are also available; however, further ...
Patrick Reteng, Linh Nguyen Thuy, Tam Tran Thi Minh, Maria Angélica Monteiro de Mello Mares-Guia, Maria Celeste Torres, Ana Maria Bispo de Filippis, Yasuko Orba, Shintaro Kobayashi, Kyoko Hayashida, Hirofumi Sawa, William W. Hall, Lan Anh Nguyen Thi, Junya Yamagishi   +12 more
doaj   +1 more source

First detection and molecular characterization of a DENV‐1/DENV‐4 co‐infection during an epidemic in Rio de Janeiro, Brazil

Clinical Case Reports, 2018
Key Clinical Message In the 80s, dengue viruses type 1 and 4 (DENV‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV‐1 introduction in the state of Rio de Janeiro (RJ) in mid‐1980s, that dengue became a nationwide ...
Fernanda de Bruycker‐Nogueira, Nieli Rodrigues da Costa Faria, Priscila Conrado Guerra Nunes, Rita Maria Ribeiro Nogueira, Ana Maria Bispo de Filippis, Flavia Barreto dos Santos   +5 more
doaj   +1 more source