Results 41 to 50 of about 42,799 (212)
The dual regulation of apoptosis by Flavivirus [PDF]
Frontiers in Microbiology, 2020 Apoptosis is a form of programmed cell death, which maintains cellular homeostasis by eliminating pathogen-infected cells. It contains three signaling pathways: death receptor pathway, mitochondria-mediated pathway and endoplasmic reticulum pathway. Its importance in host defenses is highlighted by the observation that many viruses evade, hinder or ...
Yuhong Pan +12 more
openaire +4 more sources
Tropical Medicine and Infectious Disease, 2022 Mosquito-borne diseases (MBDs), including those caused by flaviviruses, remain human health problems for developing and urbanizing economies. This cross-sectional study examined risks of flavivirus exposure through a survey regarding knowledge and ...
Long Pham-Thanh +10 more
doaj +1 more source
Flavivirus enzymes and their inhibitors
, 2021 Flaviviruses such as dengue, Japanese encephalitis, West Nile, Yellow Fever and Zika virus, cause viral hemorrhagic fever and encephalitis in humans. However, antiviral therapeutics to treat or prevent flavivirus infections are not yet available. Thus, there is pressing need to develop therapeutics and vaccines that target flavivirus infections.
Ekaterina, Knyazhanskaya +2 more
openaire +3 more sources
Neuroinvasive flavivirus infections [PDF]
Reviews in Medical Virology, 2011 SUMMARYFlaviviruses, including Dengue, West Nile, Japanese encephalitis, and Tick‐borne encephalitis virus, are major emerging human pathogens, affecting millions of individuals worldwide. Many clinically important flaviviruses elicit CNS diseases in infected hosts, including traditional “hemorrhagic” viruses, such as Dengue. This review focuses on the
Gregorius J, Sips +2 more
openaire +2 more sources
The Multiples Fates of the Flavivirus RNA Genome During Pathogenesis [PDF]
, 2018 The Flavivirus genus comprises many viruses (including dengue, Zika, West Nile and yellow fever viruses) which constitute important public health concerns worldwide. For several of these pathogens, neither antivirals nor vaccines are currently available.
Clément Mazeaud +5 more
core +1 more source
Neurological disease caused by flavivirus infections [PDF]
, 2018 The Flavivirus genus contains dozens of species with varying geographical distributions. Most flavivirus infections in humans are asymptomatic or manifest as a non-specific febrile illness, sometimes accompanied by rash or arthralgia. Certain species are
Tristan Gibbs, David J Speers
core +1 more source
Examples of recent flavivirus/alphavirus outbreaks worldwide. [PDF]
, 2020 Examples of recent flavivirus/alphavirus outbreaks worldwide.
Kalkoa Kalo (8321274) +5 more
core +1 more source
Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells
Frontiers in Immunology, 2019 Most of the world is at risk of being infected with a flavivirus such as dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, tick-borne encephalitis virus, and Zika virus, significantly impacting millions of lives. Importantly,
Mariah Hassert +2 more
doaj +1 more source
In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination. [PDF]
PLoS Neglected Tropical Diseases, 2017 Infection caused by the four serotypes of dengue virus (DENV-1-4) is a leading cause of mosquito-borne disease. Clinically-severe dengue disease is more common when secondary dengue infection occurs following prior infection with a heterologous dengue ...
Stephen S Whitehead +17 more
doaj +1 more source