Results 51 to 60 of about 60,828 (259)

In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination. [PDF]

PLoS Neglected Tropical Diseases, 2017
Infection caused by the four serotypes of dengue virus (DENV-1-4) is a leading cause of mosquito-borne disease. Clinically-severe dengue disease is more common when secondary dengue infection occurs following prior infection with a heterologous dengue ...
Stephen S Whitehead, Anna P Durbin, Kristen K Pierce, Dan Elwood, Benjamin D McElvany, Ellen A Fraser, Marya P Carmolli, Cecilia M Tibery, Noreen A Hynes, Matthew Jo, Janece M Lovchik, Catherine J Larsson, Elena A Doty, Dorothy M Dickson, Catherine J Luke, Kanta Subbarao, Sean A Diehl, Beth D Kirkpatrick   +17 more
doaj   +1 more source

Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines

Frontiers in Immunology, 2022
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan, Yuhong Pan, Yuhong Pan, Wenjun Cai, Wenjun Cai, Wenjun Cai, Anchun Cheng, Anchun Cheng, Anchun Cheng, Mingshu Wang, Mingshu Wang, Mingshu Wang, Zhongqiong Yin, Renyong Jia, Renyong Jia, Renyong Jia   +15 more
doaj   +1 more source

Mortality associated with avian reovirus infection in a free-living magpie (Pica pica) in Great Britain [PDF]

, 2015
Avian reoviruses (ARVs) cause a range of disease presentations in domestic, captive and free-living bird species. ARVs have been reported as a cause of significant disease and mortality in free-living corvid species in North America and continental ...
Cunningham, AA, Dastjerdi, A, Everest, D, Hicks, D, Horton, DL, Irvine, RM, Lawson, B, Núñez, A, Pocknell, A, Shah, S   +9 more
core   +1 more source

A glance at subgenomic flavivirus RNAs and microRNAs in flavivirus infections [PDF]

Virology Journal, 2016
The family Flaviviridae comprises a wide variety of viruses that are distributed worldwide, some of which are associated with high rates of morbidity and mortality. There are neither vaccines nor antivirals for most flavivirus infections, reinforcing the importance of research on different aspects of the viral life cycle.
Bavia, Lorena, Mosimann, Ana Luiza Pamplona, Aoki, Mateus Nóbrega, Duarte dos Santos, Claudia Nunes   +3 more
openaire   +2 more sources

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Flavivirus RNA in Phlebotomine Sandflies [PDF]

Vector-Borne and Zoonotic Diseases, 2010
Sandfly-transmitted phleboviruses, such as Toscana, sandfly fever Sicilian, and sandfly fever Naples, can cause human disease and circulate at high rates in Mediterranean countries. Previous studies have also established that viruses other than phleboviruses may be detected in and isolated from sand flies. The recent detection and isolation (in a large
/Moureau, Grégory, Ninove, L., Izri, A., Cook, S., de Lamballerie, Xavier, Charrel, R.   +5 more
openaire   +3 more sources

Molecular characterization of flaviviruses from field-collected mosquitoes in northwestern Italy, 2011–2012

Parasites & Vectors, 2014
Background The genus Flavivirus comprises several mosquito-borne species, including the zoonotic pathogens West Nile and Usutu virus, circulating in animals and humans in Italy since 1998.
Francesca Rizzo, Francesco Cerutti, Marco Ballardini, Andrea Mosca, Nicoletta Vitale, Maria Cristina Radaelli, Rosanna Desiato, Marino Prearo, Alessandra Pautasso, Cristina Casalone, Pierluigi Acutis, Simone Peletto, Maria Lucia Mandola   +12 more
doaj   +1 more source

Detection of novel insect flavivirus sequences integrated in Aedes albopictus (Diptera: Culicidae) in Northern Italy

Virology Journal, 2009
The presence of DNA sequences integrated from a new flavivirus related to Cell Fusing Agent and Kamiti River Virus was identified in wild Aedes albopictus mosquito populations from the provinces of Trentino and Padova, Northern Italy.
Tenorio Antonio, Seco Mari, Vázquez Ana, Roiz David, Rizzoli Annapaola   +4 more
doaj   +1 more source

Detection of Zika and dengue viruses in wild-caught mosquitoes collected during field surveillance in an environmental protection area in São Paulo, Brazil.

PLoS ONE, 2020
Species of the genus Flavivirus are widespread in Brazil and are a major public health concern. The country's largest city, São Paulo, is in a highly urbanized area with a few forest fragments which are commonly used for recreation.
Karolina Morales Barrio-Nuevo, Mariana Sequetin Cunha, Adriana Luchs, Aristides Fernandes, Iray Maria Rocco, Luis Filipe Mucci, Renato Pereira de Souza, Antônio Ralph Medeiros-Sousa, Walter Ceretti-Junior, Mauro Toledo Marrelli   +9 more
doaj   +1 more source