Results 71 to 80 of about 45,492 (218)
Le remodelage morphologique et fonctionnel du cytoplasme par les flavivirus
, 2017 Les infections par les flavivirus constituent un enjeu de santé publique majeur dans le monde avec dans la plupart des cas aucun traitement antiviral disponible.
Chatel-Chaix, Laurent
core +1 more source
Animals, 2020 Background: A retrospective sero-survey for evidence of West Nile virus (WNV) infection in European wild boar (Sus scorfa) was conducted in the Latium region, Italy, on stored serum samples of the period November 2011 to January 2012.
Angela Petruccelli +6 more
doaj +1 more source
Advanced Science, Volume 13, Issue 49, 3 September 2026.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
MicroorganismsWe previously reported the first-in-human assessment of three doses (2, 5, and 10 µg) of purified inactivated Zika virus vaccine (PIZV or TAK-426) in the Phase 1 ZIK-101 study (NCT03343626).
Camilo J. Acosta +5 more
doaj +1 more source
Advanced Science, Volume 13, Issue 51, 14 September 2026.Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Journal of General Virology, 2006 Flavivirus membrane fusion is mediated by a class II viral fusion protein, the major envelope protein E, and the fusion process is extremely fast and efficient. Understanding of the underlying mechanisms has been advanced significantly by the determination of E protein structures in their pre- and post-fusion conformations and by the elucidation of the
Karin, Stiasny, Franz X, Heinz
openaire +2 more sources
Advanced Science, Volume 13, Issue 51, 14 September 2026.This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source
Impact of PAF1 KO on flavivirus host dependency factors.
, 2021 (A) GSEA was performed using list of flavivirus host dependency genes. (B) Leading edge of flavivirus host dependency factors from GSEA. Heatmap represents log2 fold change relative to parental A549 following poly(I:C) treatment. (TIF)
Matthew W. Kenaston (11731556) +5 more
core +1 more source
Memorias del Instituto de Investigaciones en Ciencias de la Salud, 2017 Los flavivirus son responsables de una considerable morbi-mortalidad a nivel mundial. Entre ellos, el virus del dengue (DENV) es causante de graves problemas de salud pública en Paraguay.
Fátima María Cardozo Segovia +7 more
doaj
The International Journal of Health Planning and Management, Volume 41, Issue 5, Page 1085-1093, September 2026.ABSTRACT Background Dengue is a major mosquito‐borne viral disease worldwide, imposing significant healthcare burden on governments in countries where it is endemic, such as Mexico. This systematic review focused on studies reporting the cost of dengue in Mexico during 2010–2020.
Gilberto Sánchez‐González +2 more
wiley +1 more source