Results 91 to 100 of about 45,492 (218)
ChemistrySelect, Volume 11, Issue 33, 1 September 2026.This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira +8 more
wiley +1 more source
Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus
ChemistrySelect, Volume 11, Issue 36, 22 September 2026.Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis +8 more
wiley +1 more source
Neurological disease caused by flavivirus infections
, 2018 The Flavivirus genus contains dozens of species with varying geographical distributions. Most flavivirus infections in humans are asymptomatic or manifest as a non-specific febrile illness, sometimes accompanied by rash or arthralgia. Certain species are
Tristan Gibbs, David J Speers
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One HealthSummary: Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide.
Aaron Yeh-Gorocica +14 more
doaj +1 more source
Anais da Academia Brasileira de Ciências, 2009 Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even
Rafael Dhalia +6 more
doaj +1 more source
Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu +6 more
wiley +1 more source
Cranberry Pomace Valorization: Composition, Extraction, Bioactivity, and Food Applications
Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.ABSTRACT Cranberry pomace, the principal solid residue generated during cranberry processing, is increasingly recognized as a compositionally valuable coproduct rather than a waste material. This is particularly relevant in North America, where cranberry production is concentrated in the United States and Canada, the two leading producing countries ...
Ali Ali Redha, Tuba Esatbeyoglu
wiley +1 more source
Analysis of Molecular Interactions Between West Nile Virus and Host Cells
Members of the genus Flavivirus are positive-stand RNA viruses that can cause a variety of human diseases, including fever, encephalitis, hepatitis and hemorrhagic fevers.
Espinola Estigarribia, Emilio
core +1 more source
Bioinformatics in new generation flavivirus vaccines [PDF]
, 2010 Flavivirus infections are the most prevalent arthropod-borne infections world wide, often causing severe disease especially among children, the elderly, and the immunocompromised.
Albert D. M. E. Osterhaus +8 more
core +1 more source
Notification of the first isolation of Cacipacore virus in a human in the State of Rondônia, Brazil
Revista da Sociedade Brasileira de Medicina Tropical, 2011 Flavivirus is a genus of arthropod-transmitted viruses of the family Flaviviridae, and in Brazil, up to eleven different Flavivirus have been isolated. We collected blood from farmers in the municipality of Theobroma, which is located 320km from the City
Weber Cheli Batista +5 more
doaj +1 more source