Results 91 to 100 of about 42,662 (220)

Unusual MRI features in a case of presumed canine tick‐borne meningoencephalomyelitis

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 7‐year‐old, standard, wire‐haired dachshund presented with quickly progressive multifocal central nervous system signs, which localised to the brainstem and cervical myelopathy, including reduced cervical and thoracic limb muscle tone and withdrawal reflexes. Magnetic resonance imaging revealed bilateral, approximately symmetric, T2‐weighted
Jon Prager, Alex Smith, Hélène Vandenberghe   +2 more
wiley   +1 more source

Analysis of Molecular Interactions Between West Nile Virus and Host Cells

Members of the genus Flavivirus are positive-stand RNA viruses that can cause a variety of human diseases, including fever, encephalitis, hepatitis and hemorrhagic fevers.
Espinola Estigarribia, Emilio
core   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host

Reviews in Medical Virology, Volume 36, Issue 4, July 2026.
ABSTRACT Between mosquitoes and birds, West Nile virus (WNV) is a neurotropic flavivirus, an arthropod‐borne pathogen involved in an enzootic cycle. Additionally, it can infect both people and horses, leading to severe illness. Since 1999, WNV has spread across North and South America, including Mexico and the Caribbean.
E. Cimini, E. Tartaglia, F. Cristofanelli, S. Gili, F. Maggi   +4 more
wiley   +1 more source

Synthesis and Evaluation of Aromatic Sulfonamide and Disulfonamide Derivatives as Dengue Virus NS3–NS5 Interaction Inhibitors

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč, Jan Drahorád, Jakub Harvalík, Tereza Horáčková, Manfred Brinker, Arianna Loregian, Andrea Brancale, Beatrice Mercorelli, Petra Cuřínová   +8 more
wiley   +1 more source

Membrane and envelope virus proteins co-expressed as lysosome associated membrane protein (LAMP) fused antigens: a potential tool to develop DNA vaccines against flaviviruses

Anais da Academia Brasileira de Ciências, 2009
Vaccination is the most practical and cost-effective strategy to prevent the majority of the flavivirus infection to which there is an available vaccine. However, vaccines based on attenuated virus can potentially promote collateral side effects and even
Rafael Dhalia, Milton Maciel Jr., Fábia S.P. Cruz, Isabelle F.T. Viana, Mariana L. Palma, Thomas August, Ernesto T.A. Marques Jr.   +6 more
doaj   +1 more source

Molecular Insights and Repellent Efficacy of the Essential Oil and Major Compounds From Piper cyrtopodon (Miq.) C.DC (Piperaceae) Against Aedes aegypti (Linnaeus, 1762) (Culicidae)

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
The essential oil and major compounds from Piper cyrtopodon exhibit potent, long‐lasting repellent activity against Aedes aegypti mosquitoes, combined with low cytotoxicity and favorable molecular docking interactions with odorant‐binding proteins. These findings highlight its potential for the development of alternative products for bite prevention ...
Maria L. L. da Costa, Renata G. de Azevedo, Sergio M. Nunomura, Rita de C. S. Nunomura, Gemilson S. Pontes, Rosemary A. Roque, Tatiane P. de Souza, André C. de Oliveira   +7 more
wiley   +1 more source

Computational approaches for investigating protein-ligand interactions - towards an in-depth understanding of the dengue virus methyltransferase [PDF]

, 2013
Interactions between proteins and their ligands play crucial roles in many biological processes, such as metabolism, signaling, transport, regulation or molecular recognition. Understanding the molecular basis of protein-ligand interactions is thus of
Schmidt, Tobias Benjamin
core   +1 more source

Prevalence of Flavivirus and Alphavirus in bats captured in the state of Yucatan, southeastern Mexico

One Health
Summary: Flavivirus (family Flaviviridae) and Alphavirus (family Togaviridae) are mosquito-borne viruses that poses a significant risk to public health worldwide.
Aaron Yeh-Gorocica, Marco Torres-Castro, Claudia Carrillo-Chan, Alejandro Suarez-Galaz, Melissa Suarez-Galaz, Wilson Moguel-Chin, Alonso Panti-May, Cesar Lugo-Caballero, Henry Puerta-Guardo, Juan Chable-Santos, Pablo Manrique-Saide, Guadalupe Ayora-Talavera, Celia Selem-Salas, Mario Frias-Casas, Antonio Rivero-Juarez   +14 more
doaj   +1 more source

A Prothrombotic Shift: Cerebral Venous Sinus Thrombosis in the Recovery Phase of Dengue Fever—A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Post‐dengue cerebral venous sinus thrombosis is an uncommon complication of dengue fever. It occurs due to a prothrombotic shift during the recovery or critical phase of dengue fever, presenting usually as a persistent headache. Prompt neuroimaging and anticoagulation are crucial to a favorable prognosis, even in the presence of hemorrhagic ...
Zain Ul Abedeen, Waqar Khan, Waqar Iqbal Khan, Zia Ullah, Naeem Ullah, Abad Ur Rehman   +5 more
wiley   +1 more source

The Challenges of Flavivirus Drug Discovery

, 2011
Many flaviviruses are human pathogens of global importance, but no antiviral medicines are currently available to manage these diseases. Over the past decade, significant progress has been made towards the understanding of flavivirus biology.
Qing-Yin Wang, Pei-Yong Shi, Thomas H. Keller   +2 more
core   +1 more source