Results 81 to 90 of about 45,492 (218)

Toll-Like Receptors and RIG-I-Like Receptors Play Important Roles in Resisting Flavivirus

Journal of Immunology Research, 2018
Flaviviridae family is a class of single-stranded RNA virus, which is fatal to human and animals and mainly prevalent in subtropic and tropic countries.
Hong-Yan Guo, Xing-Cui Zhang, Ren-Yong Jia   +2 more
doaj   +1 more source

Neuronal Apoptotic Bodies Facilitate Japanese Encephalitis Virus Infection and Pathogenicity

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Japanese encephalitis (JE) caused by Japanese encephalitis virus (JEV) infection remains one of the major types of viral encephalitis. The mechanisms underlying JEV infection and pathogenesis have not been fully elucidated, resulting in the absence of specific therapies for JE. Neuronal apoptosis is a well‐established outcome of JEV infection;
Chuan Zeng, Xiaowei Nan, Ting Wang, Junyao Xiong, Shuo Zhu, Chengjie Yang, Bibo Zhu, Youhui Si, Shengbo Cao, Jing Ye   +9 more
wiley   +1 more source

Pathogenesis of flavivirus encephalitis

, 2003
Within the flavivirus family, viruses that cause natural infections of the central nervous system (CNS) principally include members of the Japanese encephalitis virus (JEV) serogroup and the tick-borne encephalitis virus (TBEV) serocomplex. The pathogenesis of diseases involves complex interactions of viruses, which differ in neurovirulence potential ...
Chambers, Thomas J, Diamond, Michael S
openaire   +2 more sources

Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus [PDF]

, 2011
We provide experimental evidence of a replication enhancer element (REE) within the capsid gene of tick-borne encephalitis virus (TBEV, genus Flavivirus).
I. M. Jones, Gould, EA, Tuplin, Andrew, Gould, E. A., A. Buckley, E. A. Gould, A. Tuplin, Tuplin, A., Jones, I. M., Jones, I. M. (Ian M.), Buckley, A., Gould, E., T. S. Gritsun, Jones, IM, Gritsun, T. S., Tuplin, A, Evans, DJ, Evans, David J., Gritsun, TS, D. J. Evans, Evans, D. J., Buckley, A   +21 more
core   +1 more source

Crystal structure of the NS3-like helicase from Alongshan virus

IUCrJ, 2020
Alongshan virus (ALSV) is an emerging human pathogen that was identified in China and rapidly spread to the European continent in 2019, raising concerns about public health.
Xiaopan Gao, Kaixiang Zhu, Justyna Aleksandra Wojdyla, Pu Chen, Bo Qin, Ziheng Li, Meitian Wang, Sheng Cui   +7 more
doaj   +1 more source

Dengue Seroprevalence Among Blood Donors in the Lazio Region (Italy): Is There an Iceberg Beneath the Surface?

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT During 2023, dengue virus (DENV) autochthonous circulation was detected in Lazio, Italy. To investigate the magnitude of the phenomenon, anti‐DENV serological status of blood donors residing in previously affected Rome municipalities was evaluated.
Martina Spaziante, Lugi Rosa, Francesca Colavita, Ilaria Mussetto, Gabriella De Carli, Valentina Vantaggio, Alessandro Agresta, Sabrina Coen, Silvia Cammisa, Alessandra D'Abramo, Gaetano Maffongelli, Stefania Vaglio, Stefano Iaboni, Ida Casorelli, Luca Mele, Luciana Teofili, Paola Scognamiglio, Andrea Siddu, Emanuele Nicastri, Fabrizio Maggi, Enrico Girardi, ARBODONORS Working Group, Deborah Ilaria Gadaleta, Diletta D'Epiro, Enrico Duranti, Manuela Cornacchia, Tecla Maria Fontana, Maria Laura Foddai, Francesca Frangiolini, Giuseppina Antonia Natale, Mafalda De Rienzo, Francesco Vairo   +31 more
wiley   +1 more source

Eugenol‐Derived Piperazine Mannich Bases as Selective Inhibitors of Mayaro Virus: In Vitro Antiviral Evaluation and Mechanistic Insights

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Arboviruses represent an ongoing global health challenge, particularly in tropical regions where diseases caused by Chikungunya virus (CHIKV) and Mayaro virus (MAYV) continue to emerge. Given the absence of licensed antiviral therapies, the identification of effective small molecules remains critical.
Adriana Cotta Cardoso Reis, Amália Luíza de Sousa da Silva, Camila Portruneli, Augusto Vieira Pontes Silva, Saulo Fehelberg Pinto Braga, Igor Rodrigues Lapa, Thiago Belarmino de Souza, Lucas Lopardi Franco, Diogo Teixeira Carvalho, Geraldo Célio Brandão   +9 more
wiley   +1 more source

Implicações do peptídeo conservado E250-270 da proteína "E" na infectividade do vírus da dengue [PDF]

, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2014Os vírus de genoma RNA apresentam uma ampla variabilidade genética, devido à ...
Fleith, Renata Cristina
core  

Examples of recent flavivirus/alphavirus outbreaks worldwide.

, 2020
Examples of recent flavivirus/alphavirus outbreaks worldwide.
Kalkoa Kalo (8321274), Phill Isaacs (8321280), Douglas Spencer Millar (8321283), Crystal Garae (8321271), George Junior Pakoa (8321277), Rohan Baker (3426029)   +5 more
core   +1 more source

The glycosylation deficiency of flavivirus NS1 attenuates virus replication through interfering with the formation of viral replication compartments

Journal of Biomedical Science
Background Flavivirus is a challenge all over the world. The replication of flavivirus takes place within membranous replication compartments (RCs) derived from endoplasmic reticulum (ER).
Shuhan Huang, Pan-Deng Shi, Xiao-Xuan Fan, Yang Yang, Cheng-Feng Qin, Hui Zhao, Lei Shi, Yali Ci   +7 more
doaj   +1 more source