Results 61 to 70 of about 45,492 (218)
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Data_Sheet_1_Seeking Flavivirus Cross-Protective Immunity.docx
The Flavivirus genus is composed by viral serocomplexes with relevant global epidemiological impact. Many areas of the world present both, vector fauna and geographical conditions compatible with co-circulation, importing, emergence, and epidemics of ...
Letícia Tsieme Gushi (7407710) +3 more
core +1 more source
Development of Double Antibody Sandwich ELISA for Detection of Duck or Goose Flavivirus
In order to establish double antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA) for detection of duck or goose flavivirus, polyclonal antibody against the flavivirus strain JS804 in geese and monoclonal antibody against the E protein of ...
Hui-min NIU +10 more
doaj +1 more source
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade +13 more
wiley +1 more source
TRIMming Flavivirus Infection [PDF]
Tripartite motif (TRIM) proteins are novel players in antiviral innate immunity. In this issue of Cell Host & Microbe,Taylor et al. (2011) discover the mechanism of action of TRIM79α and show that this interferon-induced protein restricts tick-borne flaviviruses by targeting the viral polymerase for degradation.
openaire +2 more sources
2014 Flavivirus Virus Cases [PDF]
This map depicts, by county, the number of human cases of Flavivirus Virus cases in South Carolina in ...
South Carolina Department of Health and Environmental Control, Bureau of Laboratories
core +1 more source
Impact of flavivirus vaccine-induced immunity on primary Zika virus antibody response in humans.
BackgroundZika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g.
Stefan Malafa +14 more
doaj +1 more source
Rational design of West Nile virus vaccine through large replacement of 3′ UTR with internal poly(A)
The genus Flavivirus comprises numerous emerging and re‐emerging arboviruses causing human illness. Vaccines are the best approach to prevent flavivirus diseases.
Ya‐Nan Zhang +15 more
doaj +1 more source
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier +7 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source

