Results 41 to 50 of about 58,323 (264)

New insights into control of arbovirus replication and spread by insect RNA interference pathways [PDF]

, 2012
Arthropod-borne (arbo) viruses are transmitted by vectors, such as mosquitoes, to susceptible vertebrates. Recent research has shown that arbovirus replication and spread in mosquitoes is not passively tolerated but induces host responses to control ...
Andersson, Angelini, Angelini, Arensburger, Arensburger, Attarzadeh-Yazdi, Berry, Blevins, Brackney, Chung, Cirimotich, Cohen, Czech, Ding, Dubrulle, Fagegaltier, Flynt, Franz, Ghildiyal, Henke, Holt, Hussain, Hussain, Iwasaki, Kaminker, Kawamura, Keene, Kwon, Lagos-Quintana, Li, Lim, Lucchetta, Mendes, Morazzani, Mueller, Myles, Nene, Qi, Rezza, Ruby, Saleh, Sanchez-Vargas, Schwarz, Selbach, Sijen, Siu, Skalsky, Tam, Thibault, Vodovar, Watanabe, Waterhouse, Wu, Yan, Zeiner, Zeng   +55 more
core   +3 more sources

Genetic Variations in Crimean-Congo Hemorrhagic Fever Virus: Challenges for Molecular Diagnostic Assays—A Case Report

Case Reports in Infectious Diseases
Conclusions: This report underlines the requirement of CCHFV genomic surveillance to update the molecular diagnostic assays. Moreover, the circulation of an African CCHFV strain in Iran supports previous data suggesting that Iran harbors the greatest ...
Mostafa Salehi-Vaziri, Tahmineh Jalai, Mahsa Tavakoli, Laya Farhan Asadi, Seyed Marzieh Sajadi, Tahereh Mohammadi, Sepideh Gerdooei, Sahar Khakifirouz, Farnoosh Arbabi, Arash Ghalyanchi Langeroudi, Mohammad Reza Shirzadi, Mohammad Hassan Pouriayevali   +11 more
doaj   +1 more source

Zika virus infection in the returning traveller: what every neurologist should know [PDF]

, 2018
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia, Jacobs, Bart C., Lant, Suzannah, Leonhard, Sonja Emily, Solomon, Tom, Wilder-Smith, Annelies, Willison, Hugh   +6 more
core   +6 more sources

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Plant Virus‐Induced Inheritable Apoptosis Drives Reproductive Costs in Female Insect Vectors to Balance Viral Biparental Transmission

Advanced Science, EarlyView.
Rice gall dwarf virus (RGDV), transmitted biparentally by leafhopper vector to their offspring, exploits the capsid protein to induce inheritable ovarian apoptosis via insulin‐driven PI3K/AKT/FoxO signaling axis. This mechanism enhances infection but reduces female reproductive fitness, causing inefficient maternal transmission.
Haibo Wu, Wenqiang Wan, Qingquan Liang, Hengsong Yang, Chengcong Lu, Taiyun Wei, Qian Chen   +6 more
wiley   +1 more source

Transfusion-transmitted arboviruses [PDF]

Vox Sanguinis, 2010
There exists considerable risk for transfusion transmission of arboviruses due to short periods of asymptomatic viraemia in populations with variable and sometimes extremely high incidence of arboviral infections. Aside from West Nile virus, few arbovirus transfusion transmissions have been proven, mostly due to difficulties in ruling out vector-borne ...
L R, Petersen, M P, Busch
openaire   +2 more sources

Distribution and Characterisation of Tick-Borne Flavi-, Flavi-like, and Phenuiviruses in the Chelyabinsk Region of Russia

Viruses, 2022
In this work, we presented data from a two-year study of flavi-, flavi-like, and phenuiviruses circulation in the population of ixodid ticks in the Chelyabinsk region. We isolated three tick-borne encephalitis virus (TBEV) strains from I.
Ivan S. Kholodilov, Oxana A. Belova, Anna Y. Ivannikova, Magomed N. Gadzhikurbanov, Marat T. Makenov, Alexander S. Yakovlev, Alexandra E. Polienko, Alena V. Dereventsova, Alexander G. Litov, Larissa V. Gmyl, Egor V. Okhezin, Svetlana V. Luchinina, Alexander S. Klimentov, Galina G. Karganova   +13 more
doaj   +1 more source

Historical Patterns of Arboviral Seroprevalence across Africa and Asia [PDF]

, 2017
The emergence and resurgence of arboviruses in recent history is challenging our scientific understanding of mosquito-borne diseases and their transmission.
Chrisafis, George C
core   +1 more source

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Possible Arbovirus Found in Virome of Melophagus ovinus

Viruses, 2021
Members of the Lipopteninae subfamily are blood-sucking ectoparasites of mammals. The sheep ked (Melophagus ovinus) is a widely distributed ectoparasite of sheep.
Alexander G. Litov, Oxana A. Belova, Ivan S. Kholodilov, Magomed N. Gadzhikurbanov, Larissa V. Gmyl, Natalia D. Oorzhak, Anna A. Saryglar, Aydar A. Ishmukhametov, Galina G. Karganova   +8 more
doaj   +1 more source