Results 21 to 30 of about 146,822 (252)
A Novel Peptide Derived from Arca inflata Induces Apoptosis in Colorectal Cancer Cells through Mitochondria and the p38 MAPK Pathway
Marine Drugs, 2022 Colorectal carcinoma (CRC) is one of the major causes of cancer-related incidence and deaths. Here, we identified a novel antitumor peptide, P6, with a molecular weight of 2794.8 Da from a marine Chinese medicine, Arca inflata Reeve.Chunlei Li, Sirui Zhang, Jianhua Zhu, Weijuan Huang, Y. Luo, Hui Shi, Dongbo Yu, Liguo Chen, Liyan Song, R. Yu +9 moresemanticscholar +1 more sourceDisrupting the ArcA Regulatory Network Amplifies the Fitness Cost of Tetracycline Resistance in Escherichia coli
mSystems, 2022 Antimicrobial resistance (AMR) is projected to be the cause of >10 million deaths annually by 2050. While efforts to find new potent antibiotics are effective, they are expensive and outpaced by the rate at which new resistant strains emerge.Mario L. Arrieta-Ortiz, Min Pan, Amardeep Kaur, Evan Pepper-Tunick, V. Srinivas, Ananya Dash, S. C. Immanuel, A. Brooks, T. Shepherd, N. Baliga +9 moresemanticscholar +1 more sourceThe ARCA Registry: A Collaborative Global Platform for Advancing Trial Readiness in Autosomal Recessive Cerebellar Ataxias
Frontiers in Neurology, 2021 Autosomal recessive cerebellar ataxias (ARCAs) form an ultrarare yet expanding group of neurodegenerative multisystemic diseases affecting the cerebellum and other neurological or non-neurological systems. With the advent of targeted therapies for ARCAs, A. Traschütz, S. Reich, Astrid D. Adarmes, M. Anheim, M. Ashrafi, J. Baets, A. Başak, E. Bertini, Bernard Brais, C. Gagnon, J. Gburek-Augustat, H. Hanağası, Anna Heinzmann, R. Horvath, P. de Jonghe, C. Kamm, P. Klivényi, T. Klopstock, M. Minnerop, A. Münchau, M. Renaud, R. Roxburgh, F. Santorelli, T. Schirinzi, D. Sival, D. Timmann, S. Vielhaber, M. Wallner, B. P. van de Warrenburg, G. Zanni, S. Zuchner, T. Klockgether, R. Schüle, L. Schöls, M. Synofzik +34 moresemanticscholar +1 more sourceTwo novel antioxidant peptides derived from Arca subcrenata against oxidative stress and extend lifespan in Caenorhabditis elegans
, 2021 Arca subcrenata has been used as a nutritious food material and traditional medicine in China for centuries. Two novel antioxidant peptides, D2-G1S-1 (VENAACTTNEECCEKK) and G2-G1S-2 (VEGGAACTTGGEEGCCEKK), were identified from A.Hui Shi, Xuqiao Hu, Hang Zheng, Chunlei Li, Lianli Sun, Zhongyi Guo, Weijuan Huang, R. Yu, Liyan Song, Jianhua Zhu +9 moresemanticscholar +1 more sourceImmunomodulatory activity of polysaccharide from Arca granosa Linnaeus via TLR4/MyD88/NFκB and TLR4/TRIF signaling pathways
, 2021 The immune effect and the underlying molecular mechanisms of AGPp, a purified polysaccharide extracted from Arca granosa, have been studied in RAW264.7 in vitro.Lijun Zhu, Wei Li, Ziying Fan, Xianying Ye, R. Lin, Mengmeng Ban, L. Ren, Xiaoqing Chen, Danyan Zhang +8 moresemanticscholar +1 more sourceAstronomy potential of KM3NeT/ARCA [PDF]
The European Physical Journal CThe KM3NeT/ARCA neutrino detector is currently under construction at 3500 m depth offshore Capo Passero, Sicily, in the Mediterranean Sea. The main science objectives are the detection of high-energy cosmic neutrinos and the discovery of their sources ...S. Aiello, A. Albert, M. Alshamsi, S. Alves Garre, Z. Aly, A. Ambrosone, F. Ameli, M. André, E. Androutsou, M. Anguita, L. Aphecetche, M. Ardid, S. Ardid, H. Atmani, J. Aublin, F. Badaracco, L. Bailly-Salins, Z. Bardacová, B. Baret, A. Bariego-Quintana, A. Baruzzi, S. Basegmez du Pree, Y. Becherini, M. Bendahman, F. Benfenati, M. Benhassi, D. M. Benoit, E. Berbee, V. Bertin, S. Biagi, M. Boettcher, D. Bonanno, J. Boumaaza, M. Bouta, M. Bouwhuis, C. Bozza, R. Bozza, H. Brânzaș, F. Bretaudeau, M. Breuhaus, R. Bruijn, J. Brunner, R. Bruno, E. Buis, R. Buompane, J. Busto, B. Caiffi, D. Calvo, S. Campion, A. Capone, F. Carenini, V. Carretero, T. Cartraud, P. Castaldi, V. Cecchini, S. Celli, L. Cerisy, M. Chabab, M. Chadolias, A. Chen, S. Cherubini, T. Chiarusi, M. Circella, R. Cocimano, J. Coelho, A. Coleiro, R. Coniglione, P. Coyle, A. Creusot, G. Cuttone, R. Dallier, Y. Darras, A. De Benedittis, B. De Martino, V. Decoene, R. Del Burgo, I. Del Rosso, L. S. Di Mauro, I. Di Palma, A. Díaz, C. Díaz, D. Diego-Tortosa, C. Distefano, A. Domi, C. Donzaud, D. Dornic, M. Dörr, E. Drakopoulou, D. Drouhin, J. Ducoin, R. Dvornick'y, T. Eberl, E. Eckerová, A. Eddymaoui, T. van Eeden, M. Eff, D. van Eijk, I. El Bojaddaini, S. El Hedri, A. Enzenhöfer, G. Ferrara, M. Filipović, F. Filippini, D. Franciotti, L. Fusco, J. Gabriel, S. Gagliardini, T. Gál, J. García Méndez, A. Garcia Soto, C. Gatius Oliver, N. Geißelbrecht, H. Ghaddari, L. Gialanella, B. K. Gibson, E. Giorgio, I. Goos, P. Goswami, D. Goupillière, S. Gozzini, R. Gracia, K. Graf, C. Guidi, B. Guillon, M. Gutiérrez, H. van Haren, A. Heijboer, A. Hekalo, L. Hennig, J. Hernández-Rey, W. Idrissi Ibnsalih, G. Illuminati, M. de Jong, P. de Jong, B. Jung, P. Kalaczyński, O. Kalekin, U. Katz, G. Kistauri, C. Kopper, A. Kouchner, V. Kueviakoe, V. Kulikovskiy, R. Kvatadze, M. Labalme, R. Lahmann, G. Larosa, C. Lastoria, A. Lazo, S. Le Stum, G. Lehaut, E. Leonora, N. Lessing, G. Levi, M. Lindsey Clark, F. Longhitano, F. Magnani, J. Majumdar, L. Malerba, F. Mamedov, J. Manczak, A. Manfreda, M. Marconi, A. Margiotta, A. Marinelli, C. Markou, L. Martin, J. Martínez‐Mora, F. Marzaioli, M. Mastrodicasa, S. Mastroianni, S. Miccichè, G. Miele, P. Migliozzi, E. Migneco, M. Mitsou, C. Mollo, L. Morales-Gallegos, M. Morga, A. Moussa, I. Mozun Mateo, R. Muller, M. R. Musone, M. Musumeci, S. Navas, A. Nayerhoda, C. Nicolau, B. Nkosi, B. Ó Fearraigh, V. Oliviero, A. Orlando, E. Oukacha, D. Paesani, J. Palacios González, G. Papalashvili, V. Parisi, E. P. Pastor Gomez, A. Paun, G. Pavalas, I. Pelegris, S. Peña Martínez, M. Perrin-Terrin, J. Perronnel, V. Pestel, R. Pestes, P. Piattelli, C. Poirè, V. Popa, T. Pradier, J. Prado, S. Pulvirenti, C. A. Quiroz-Rangel, U. Rahaman, N. Randazzo, R. Randriatoamanana, S. Razzaque, I. C. Rea, D. Real, G. Riccobene, J. Robinson, A. Romanov, A. Saina, F. Salesa Greus, D. Samtleben, A. Sánchez Losa, S. Sanfilippo, M. Sanguineti, C. Santonastaso, D. Santonocito, P. Sapienza, J. Schnabel, J. Schumann, H. M. Schutte, J. Seneca, N. Sennan, B. Setter, I. Sgura, R. Shanidze, A. Sharma, Y. Shitov, F. Šimkovic, A. Simonelli, A. Sinopoulou, M. Smirnov, B. Spisso, M. Spurio, D. Stavropoulos, I. Stekl, M. Taiuti, Y. Tayalati, H. Thiersen, I. Tosta e Melo, E. Tragia, B. Trocmé, V. Tsourapis, A. Tudorache, E. Tzamariudaki, A. Vacheret, A. Valer Melchor, V. Valsecchi, V. Van Elewyck, G. Vannoye, G. Vasileiadis, F. Vazquez de Sola, C. Verilhac, A. Veutro, S. Viola, D. Vivolo, J. Wilms, E. de Wolf, H. Yepes-Ramirez, G. Zarpapis, S. Zavatarelli, A. Zegarelli, D. Zito, J. Zornoza, J. Zúñiga, N. Żywucka +277 moresemanticscholar +1 more source