Results 31 to 40 of about 6,960,427 (243)

Aortic Geometric Alteration Associated With Acute Type B Aortic Dissection: Angulation, Tortuosity, and Arch Type

Frontiers in Physiology, 2021
Background: Acute type B aortic dissection is a highly serious aortic pathology. Aortic geometric parameters may be useful variables related to the occurrence of acute type B aortic dissection (aTBAD).
Likun Sun, Likun Sun, Jiehua Li, Jiehua Li, Lunchang Wang, Lunchang Wang, Quanming Li, Quanming Li, Hao He, Hao He, Xin Li, Xin Li, Ming Li, Ming Li, Tun Wang, Tun Wang, Chenglei Zhao, Chenglei Zhao, Xiaolong Zhang, Xiaolong Zhang, Chang Shu, Chang Shu, Chang Shu   +22 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Semi- and Nonparametric ARCH Processes

Journal of Probability and Statistics, 2011
ARCH/GARCH modelling has been successfully applied in empirical finance for many years. This paper surveys the semiparametric and nonparametric methods in univariate and multivariate ARCH/GARCH models.
Oliver B. Linton, Yang Yan
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

CORRELATION BETWEEN DURATION OF BOTTLE-FEEDING AND DENTAL ARCH MEASUREMENT IN DECIDUOUS DENTITION

Journal of Dentistry Indonesia, 2015
The purpose of this study was to observe the correlation between duration of bottle feeding and dental arch measurement in deciduous dentition. Duration of bottle feeding was divided into 4 groups: ≤ 24 months, 25 – 36 months, 37 – 48 months, and > 48
Meldo Mahniza, Retno Hayati, Sri Harini
doaj   +1 more source

Re–assessment of Pont’s index in Class I normal occlusion [PDF]

Al-Rafidain Dental Journal, 2006
Background: Since the introduction of modern orthodontics, several indices have been proposed to help prediction normal maxillary arch width that would relieve crowding, maintain occlusion stability and reduces future relapse.
Huda A Al–Sarraf, Ahmed A Abdul–Mawjood, Nada M Al–Sayagh   +2 more
doaj   +1 more source

Research on the Mechanical Performance of a Mountainous Long-Span Steel Truss Arch Bridge with High and Low Arch Seats

Buildings, 2023
The Loushui River Bridge is a mountainous long-span steel truss arch bridge with high and low arch seats. The design and construction of the bridge follow the principle of minimizing environmental damage and promoting sustainable development.
Yao Tan, Junfeng Shi, Peng Liu, Jun Tao, Yueyue Zhao   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source