Nature CommunicationsTnpBs encoded by the IS200/IS605 family transposon are among the most abundant prokaryotic proteins from which type V CRISPR-Cas nucleases may have evolved.
Xu Feng +12 more
doaj +1 more source
Exploring the Gut‐Prostate Axis: Microbial Signatures Linked to Prostate Volume and Bladder Function
The Prostate, EarlyView.ABSTRACT Background Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men, often linked to systemic inflammation and metabolic dysfunction. Emerging evidence suggests that the gut microbiome may contribute to prostate health and disease.
Jonathan Surber +12 more
wiley +1 more source
The Curious Case of CysE: Diversity and Distribution of Serine Acetyltransferases in Bacteria
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT Serine acetyltransferase (CysE) is a member of the left‐handed β‐helix family of acetyltransferases that catalyze the rate limiting step in de novo cysteine biosynthesis. There are two isoforms of CysE that differ in length, with the shorter isoform lacking approximately 76 amino acids at the N‐terminus of the protein from the serine ...
Keely E. A. Oldham +3 more
wiley +1 more source
Global Warming and Mass Extinctions Associated With Large Igneous Province Volcanism
Geophysical Monograph Series, Page 83-102., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
David P. G. Bond, Yadong Sun
wiley +1 more source
Length, Protein-Protein Interactions, and Complexity
, 2004 The evolutionary reason for the increase in gene length from archaea to prokaryotes to eukaryotes observed in large scale genome sequencing efforts has been unclear.
Albert +27 more
core +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT We present the first x‐ray crystallographic structural evidence of an archaeal DNA ligase showing the AMP covalent adduct together with further cofactor hydrolysis, capturing a transient intermediary in the first step of the ligation reaction, triggered by the pyrophosphate hydrolysis.
A. X. Quintana‐Armas +3 more
wiley +1 more source
Method for automated high performance closed batch cultivation of gas-utilizing methanogens
AMB ExpressTo advance the utilization of microbial cell factories in gas fermentation processes, their physiological and biotechnological characteristics must be understood.
Walter Hofmann +6 more
doaj +1 more source
Early evolution of purple retinal pigments on Earth and implications for exoplanet biosignatures
, 2018 We propose that retinal-based phototrophy arose early in the evolution of life on Earth, profoundly impacting the development of photosynthesis and creating implications for the search for life beyond our planet.
DasSarma, Shiladitya +1 more
core +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
, 2018 Molecular chaperones promote the correct folding of proteins in aggregation-prone cellular environments by stabilizing nascent polypeptide chains and providing appropriate folding conditions. Prefoldins (PFDs) are molecular chaperones found in archaea and eukaryotes, generally characterized by a unique jellyfish-like hexameric structure consisting of a
Lim, S, Glover, DJ, Clark, DS
openaire +3 more sources