Results 301 to 310 of about 165,703 (375)
Structure of the Saccharolobus solfataricus GINS tetramer. [PDF]
Shankar S, Enemark EJ.
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Versatile roles of disordered transcription factor effector domains in transcriptional regulation
Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, facilitating condensate formation to enhance transcriptional efficiency, modulating DNA‐binding specificity through genome scanning, and serving as hubs ...
Rhea R. Datta+3 more
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An unusual glycerol-3-phosphate dehydrogenase in Sulfolobus acidocaldarius elucidates the diversity of glycerol metabolism across Archaea. [PDF]
Schmerling C+14 more
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Bacterial transcriptional repressor NrdR – a flexible multifactorial nucleotide sensor
NrdR is a bacterial transcription factor that regulates the expression of all three types of ribonucleotide reductase, an essential enzyme for cell survival, in response to intracellular ATP and dATP levels. We have carried out a comprehensive biochemical, biophysical and structural study of the response of E. coli NrdR to ATP and dATP.
Inna Rozman Grinberg+9 more
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Human Milk Archaea Associated with Neonatal Gut Colonization and Its Co-Occurrence with Bacteria. [PDF]
Salas-López M+9 more
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The multidomain glycosidase MDG from the hyperthermophilic euryarchaeon Thermococcus sp. contains five protein domains: three catalytic domains (GH5, GH12‐1, and GH12‐2) and two cellulose‐binding modules (CBM2). In this study, the GH12‐1 and GH12‐2 domains were individually purified and biochemically characterized.
Kseniya S. Zayulina+11 more
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Antiviral defense systems in the rumen microbiome. [PDF]
Sáenz JS, Rios-Galicia B, Seifert J.
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The radical SAM enzyme NirJ is responsible for the removal of two propionate side chains from its substrate didecarboxy‐siroheme during heme d1 biosynthesis. The cleavage products of the NirJ reaction were not known so far. In this study, it is shown that acrylate is formed as the reaction byproduct and that the resulting tetrapyrrole product carries ...
Heike Meyer+5 more
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