Results 91 to 100 of about 1,586,071 (235)

Influences of soil properties on archaeal diversity and distribution in the McMurdo Dry Valleys, Antarctica [PDF]

, 2011
The Antarctic Dry Valleys are characterized by extremely low temperatures, arid conditions, high salinity and virtual absence of plants. Therefore, food webs of these microbially dominated soils are among the simplest on earth making these mineral soils ...
Richter, Ingrid
core  

Clusters of orthologous genes for 41 archaeal genomes and implications for evolutionary genomics of archaea

Biology Direct, 2007
Background An evolutionary classification of genes from sequenced genomes that distinguishes between orthologs and paralogs is indispensable for genome annotation and evolutionary reconstruction.
Wolf Yuri I, Novichkov Pavel S, Sorokin Alexander V, Makarova Kira S, Koonin Eugene V   +4 more
doaj   +1 more source

Structural and mutational analysis of Methanosarcina mazei prenylated FMN synthase reveals the basis of its unique prenyl donor substrate specificity

The FEBS Journal, EarlyView.
Some prenylated flavin mononucleotide (prFMN) synthases exceptionally prefer dimethylallyl phosphate (DMAP) over dimethylallyl diphosphate (DMAPP), which is a common prenyl donor substrate for many prenyltransferases. Structural and mutagenic analyses of Methanosarcina mazei prFMN synthase, which prefers DMAP but can also accept DMAPP, elucidated its ...
Sou Fukuhara, Hideaki Unno, Soma Ishimine, Ryuhei Nagata, Tomokazu Ito, Hisashi Hemmi   +5 more
wiley   +1 more source

The CMG (CDC45/RecJ, MCM, GINS) complex is a conserved component of the DNA replication system in all archaea and eukaryotes

Biology Direct, 2012
Background In eukaryotes, the CMG (CDC45, MCM, GINS) complex containing the replicative helicase MCM is a key player in DNA replication. Archaeal homologs of the eukaryotic MCM and GINS proteins have been identified but until recently no homolog of the ...
Makarova Kira S, Koonin Eugene V, Kelman Zvi   +2 more
doaj   +1 more source

Crystal structure of human NIF3‐like protein reveals dynamic hexameric assembly with a single divalent metal binding site

The FEBS Journal, EarlyView.
We present the first crystal structures of human NIF3, revealing a dynamic, hexameric ring with a central cavity regulated by flexible insertion domains. Crucially, human NIF3 features a mononuclear zinc‐binding site, marking a distinct evolutionary departure from the dinuclear centers of bacterial homologs.
Elżbieta Wątor‐Wilk, Krzysztof Żak, Piotr Wilk, Paweł Kochanowski, Agnieszka Maślanka, Łukasz Skalniak, Przemysław Grudnik   +6 more
wiley   +1 more source

The first crystal structure of an archaeal helical repeat protein [PDF]

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2005
The crystal structure of ST1625p, a protein encoded by a hypothetical open reading frame ST1625 in the genome of the hyperthermophilic archaeon Sulfolobus tokodaii, was determined at 2.2 A resolution. The only sequence similarity exhibited by the amino-acid sequence of ST1625p was a 33% identity with the sequence of SSO0983p from S. solfataricus.
Yoneda, Kazunari, Sakuraba, Haruhiko, Tsuge, Hideaki, Katunuma, Nobuhiko, Kuramitsu, Seiki, Kawabata, Takeshi, Ohshima, Toshihisa   +6 more
openaire   +2 more sources

Uncovering the prevalence, key biogenesis enzymes, and biological significance of archaeal lipoproteins

Nature Communications
Lipid-anchored proteins are integral components of cell surfaces. In bacteria, lipidation of proteins with a conserved lipobox motif ([L/V/I]−3 [A/S/T/V/I]−2 [G/A/S]−1 [C]+1) is catalyzed by prolipoprotein diacylglyceryl transferase (Lgt).
Yirui Hong, Kira S. Makarova, Andy A. Garcia, Rachel Xu, Friedhelm Pfeiffer, Paula V. Welander, Mechthild Pohlschroder   +6 more
doaj   +1 more source

Proposed Role for KaiC-Like ATPases as Major Signal Transduction Hubs in Archaea

mBio, 2017
All organisms must adapt to ever-changing environmental conditions and accordingly have evolved diverse signal transduction systems. In bacteria, the most abundant networks are built around the two-component signal transduction systems that include ...
Kira S. Makarova, Michael Y. Galperin, Eugene V. Koonin   +2 more
doaj   +1 more source

Archaeal Cytoskeletal Protein CetZ1 Influences Assembly of the Motility Machinery

Molecular Microbiology, EarlyView.
The Haloferax volcanii tubulin‐like protein CetZ1 is required for rod‐cell morphogenesis and motility. We show that CetZ1 loss or GTPase inactivation impairs assembly of the motility machinery, including the archaellum base protein ArlD, the chemotaxis adaptor CheW1, and the response regulator CheY.
Hannah J. Brown, Md Imtiazul Islam, Juanfang Ruan, Matthew A. B. Baker, Solenne Ithurbide, Iain G. Duggin   +5 more
wiley   +1 more source

Identification of archaeal proteins that affect the exosome function in vitro [PDF]

BMC Biochemistry, 2010
Abstract Background The archaeal exosome is formed by a hexameric RNase PH ring and three RNA binding subunits and has been shown to bind and degrade RNA in vitro. Despite extensive studies on the eukaryotic exosome and on the proteins interacting with this complex, little information is yet available on the ...
Luz, Juliana S, Ramos, Celso RR, Santos, Márcia CT, Coltri, Patricia P, Palhano, Fernando L, Foguel, Debora, Zanchin, Nilson IT, Oliveira, Carla C   +7 more
openaire   +2 more sources